Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFR-mutant non-small cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

Guangzhi Ma; Jing Zhang; Hai Jiang; Nannan Zhang; Liyuan Yin; Wen Li; Qinghua Zhou

doi:10.18632/oncotarget.19681

Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFR-mutant non-small cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

Oncotarget ◽

10.18632/oncotarget.19681 ◽

2017 ◽

Vol 8 (59) ◽

pp. 99429-99437 ◽

Cited By ~ 6

Author(s):

Guangzhi Ma ◽

Jing Zhang ◽

Hai Jiang ◽

Nannan Zhang ◽

Liyuan Yin ◽

...

Keyword(s):

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

T790m Mutation ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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MiR-200c-3p suppression is associated with development of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer via a mediating epithelial-to-mesenchymal transition (EMT) process

Cancer Biomarkers ◽

10.3233/cbm-191119 ◽

2020 ◽

Vol 28 (3) ◽

pp. 351-363

Author(s):

Hsin-Yi Wang ◽

Yi-Nan Liu ◽

Shang-Gin Wu ◽

Chia-Lang Hsu ◽

Tzu-Hua Chang ◽

...

Keyword(s):

Epithelial To Mesenchymal Transition ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Mesenchymal Transition ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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Impact of clinical features on the efficacy of osimertinib treatment in epidermal growth factor receptor mutant non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors due to T790M mutation

Journal of Thoracic Disease ◽

10.21037/jtd.2019.08.117 ◽

2019 ◽

Vol 11 (S15) ◽

pp. S1847-S1851

Author(s):

Chong-Kin Liam ◽

Mau-Ern Poh ◽

Yong-Sheng Liam

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

T790m Mutation ◽

Lung Cancer Patients ◽

Epidermal Growth ◽

Receptor Mutant

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467P Efficacy of cranial radiotherapy prior to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer patients with brain metastases

Annals of Oncology ◽

10.1093/annonc/mdv532.51 ◽

2015 ◽

Vol 26 ◽

pp. ix125

Author(s):

N. Tsushita ◽

Y. Goto ◽

H. Shiraishi ◽

K. Tsuruoka ◽

K. Yoshida ◽

...

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Cranial Radiotherapy ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant

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The prognostic role of pretreatment epidermal growth factor receptor T790M mutation in advanced non-small cell lung cancer patients treated with EGFR tyrosine kinase inhibitors

Oncotarget ◽

10.18632/oncotarget.16222 ◽

2017 ◽

Vol 8 (31) ◽

pp. 50941-50948 ◽

Cited By ~ 5

Author(s):

Guangzhi Ma ◽

Jing Zhang ◽

Liyuan Yin ◽

Hai Jiang ◽

Weiwei Zhang ◽

...

Keyword(s):

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Prognostic Role ◽

T790m Mutation ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Tumor heterogeneity affects the activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR mutant non-small cell lung cancer (NSCLC) patients (pts)

Annals of Oncology ◽

10.1093/annonc/mdw332.03 ◽

2016 ◽

Vol 27 ◽

pp. iv4

Author(s):

N. Normanno ◽

A.M. Rachiglio ◽

M. Lambiase ◽

F. Fenizia ◽

A. Iannaccone ◽

...

Keyword(s):

Lung Cancer ◽

Tumor Heterogeneity ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Nsclc Patients

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Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer patients harboring activating EGFR mutations

Lung Cancer ◽

10.1016/j.lungcan.2015.01.004 ◽

2015 ◽

Vol 87 (3) ◽

pp. 311-317 ◽

Cited By ~ 31

Author(s):

Chang Dong Yeo ◽

Ki Hoon Park ◽

Chan Kwon Park ◽

Sang Haak Lee ◽

Seung Joon Kim ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Egfr Mutations ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Making progress in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer by surpassing resistance: third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)

Annals of Translational Medicine ◽

10.21037/atm.2017.10.04 ◽

2018 ◽

Vol 6 (8) ◽

pp. 140-140 ◽

Cited By ~ 8

Author(s):

Giannis Mountzios

Keyword(s):

Lung Cancer ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Third Generation ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Egfr Tkis

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Uncommon mutation types of epidermal growth factor receptor and response to EGFR tyrosine kinase inhibitors in Chinese non-small cell lung cancer patients

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-017-3464-9 ◽

2017 ◽

Vol 80 (6) ◽

pp. 1179-1187 ◽

Cited By ~ 7

Author(s):

Kaiyan Chen ◽

Xiaoqing Yu ◽

Haiyang Wang ◽

Zhiyu Huang ◽

Yanjun Xu ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are effective for leptomeningeal metastasis from non-small cell lung cancer patients with sensitive EGFR mutation or other predictive factors of good response for EGFR TKI

Lung Cancer ◽

10.1016/j.lungcan.2008.10.016 ◽

2009 ◽

Vol 65 (1) ◽

pp. 80-84 ◽

Cited By ~ 87

Author(s):

Hyeon Gyu Yi ◽

Hye Jin Kim ◽

Yu Jung Kim ◽

Sae-Won Han ◽

Do-Youn Oh ◽

...

Keyword(s):

Kinase Inhibitors ◽

Egfr Mutation ◽

Growth Factor Receptor ◽

Leptomeningeal Metastasis ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Tki

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Tumor heterogeneity affects the activity of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR mutant non-small cell lung cancer (NSCLC) patients (pts)

Annals of Oncology ◽

10.1093/annonc/mdw383.35 ◽

2016 ◽

Vol 27 ◽

pp. vi427

Author(s):

N. Normanno ◽

A.M. Rachiglio ◽

M. Lambiase ◽

F. Fenizia ◽

A. Iannaccone ◽

...

Keyword(s):

Lung Cancer ◽

Tumor Heterogeneity ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Egfr Mutant ◽

Nsclc Patients

Download Full-text