scholarly journals Real-Time Ultrasound Image Fusion with FDG-PET/CT to Perform Fused Image-Guided Fine-Needle Aspiration in Neck Nodes: Feasibility and Diagnostic Value

2021 ◽  
Author(s):  
P.K. de Koekkoek-Doll ◽  
M. Maas ◽  
W. Vogel ◽  
J. Castelijns ◽  
L. Smit ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fdg Pet ◽  
Ultrasound Image ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Image Guided ◽  
Pet Ct ◽  
Fused Image ◽  
Fdg Pet Ct

scholarly journals Hürthle Cells on Fine-Needle Aspiration Cytology Are Important for Risk Assessment of Focally PET/CT FDG Avid Thyroid Nodules

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3544
Author(s):  
David N. Poller ◽  
Hakim Megadmi ◽  
Matthew J. A. Ward ◽  
Pierpaolo Trimboli
Keyword(s):  
Fine Needle Aspiration ◽  
Fdg Pet ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Follicular Neoplasm ◽  
Fine Needle ◽  
Hürthle Cell ◽  
Pet Ct ◽  
Risk Of Malignancy ◽  
Fdg Pet Ct

This study assesses the role of [18F] FDG PET/CT, fine needle aspiration (FNA) cytology and ultrasound in the 1–2% of patients with focally positive thyroid nodules on FDG PET/CT. All FDG PET/CT scans with focally increased thyroid FDG PET/CT uptake performed over 37 months in one institution were matched to patients undergoing thyroid FNA. Diffuse FDG PET/CT uptake patients were excluded. A total of 47 patients showed focally increased thyroid uptake. Consistent with previous studies, 18 (38.2%) patients had malignancy—12 primary thyroid carcinoma, 1 parathyroid carcinoma, 3 metastatic carcinoma to the thyroid and 2 lymphoma. A total of 15 (31.9%) lesions categorized as non-malignant contained Hürthle cells/oncocytes. A total of 14 lesions (29.8%) had focally increased FDG PET/CT uptake with no specific cytological or histopathological cause identified. No focally PET avid Hürthle cell/oncocytic lesions were found to be malignant. Exclusion of oncocytic lesions increased the calculated risk of malignancy (ROM) of focally PET avid nodules from 38% to 68%. It may be useful to exclude focally FDG PET/CT avid Hürthle cell/oncocytic lesions, typically reported as follicular neoplasm or suspicious for a follicular neoplasm, Hürthle cell type (Oncocytic) type, RCPath Thy 3F: Bethesda IV or sometimes Thy 3a: Bethesda III FNAs) from ROM calculations. Oncocytic focally PET/CT FDG avid lesions appear of comparatively lower risk of malignancy and require investigation or operation but these lesions should be readily identified by FNA cytology on diagnostic work up of focally PET avid thyroid nodules.

False-positive FDG PET/CT uptake in Warthin tumor in head and neck oncological patients confirmed by a fine needle aspiration

2011 ◽  
Vol 40 (3) ◽  
pp. 282-284 ◽  
Author(s):  
Jerzy Klijanienko ◽  
Slavomir Petras ◽  
Lucile De Bosschere ◽  
Benoît Paulmier ◽  
Christophe Le Tourneau ◽  
...  
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
False Positive ◽  
Fdg Pet ◽  
Needle Aspiration ◽  
Warthin Tumor ◽  
Fine Needle ◽  
Oncological Patients ◽  
Pet Ct ◽  
Fdg Pet Ct

Fine-needle aspiration in all thyroid incidentalomas at 18 F-FDG PET/CT: Can EU-TIRADS revise the dogma?

2018 ◽  
Vol 89 (5) ◽  
pp. 642-648 ◽  
Author(s):  
Pierpaolo Trimboli ◽  
Gaetano Paone ◽  
Giorgio Treglia ◽  
Camilla Virili ◽  
Teresa Ruberto ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fdg Pet ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Pet Ct ◽  
Fdg Pet Ct

Metastatic Lung Nodule Diagnosed on 18F-FDG PET/CT-Guided Fine Needle Aspiration in a Patient With Renal Cell Carcinoma

2013 ◽  
Vol 38 (1) ◽  
pp. e38-e39 ◽  
Author(s):  
Kuruva Manohar ◽  
Anish Bhattacharya ◽  
Sameer Vyas ◽  
Pranab Dey ◽  
Arup Kumar Mandal ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Fine Needle Aspiration ◽  
Lung Nodule ◽  
Needle Aspiration ◽  
Ct Guided ◽  
Fine Needle ◽  
Pet Ct ◽  
Metastatic Lung ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals A Comparison between18F-FDG PET/CT Imaging and Biological and Radiological Findings in Restaging of Hepatoblastoma Patients

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Angelina Cistaro ◽  
Giorgio Treglia ◽  
Manuela Pagano ◽  
Piercarlo Fania ◽  
Valentina Bova ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Disease Recurrence ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Diagnostic Information ◽  
Disease Extent ◽  
Pet Ct ◽  
Negative Findings ◽  
Definition Of ◽  
Fdg Pet Ct

Background. In this study we retrospectively evaluated if18F-FDG-PET/CT provided incremental diagnostic information over CI in a group of hepatoblastoma patients performing restaging.Procedure. Nine patients (mean age: 5.9 years; range: 3.1–12 years) surgically treated for hepatoblastoma were followed up by clinical examination, serumα-FP monitoring, and US. CI (CT or MRI) and PET/CT were performed in case of suspicion of relapse. Fine-needle aspiration biopsies (FNAB) were carried out for final confirmation if the results of CI, PET/CT, and/orα-FP levels were suggestive of relapse. PET/CT and CI findings were analyzed for comparison purposes, using FNAB as reference standard.Results.α-FP level was suggestive of disease recurrence in 8/9 patients. Biopsy was performed in 8/9 cases. CI and PET/CT resulted to be concordant in 5/9 patients (CI identified recurrence of disease, but18F-FDG-PET/CT provided a better definition of disease extent); in 4/9 cases, CI diagnostic information resulted in negative findings, whereas PET/CT correctly detected recurrence of disease.18F-FDG-PET/CT showed an agreement of 100% (8/8) with FNAB results.Conclusions.18F-FDG-PET/CT scan seems to better assess HB patients with respect to CI and may provide incremental diagnostic value in the restaging of this group of patients.

scholarly journals Performance of 18F-FDG PET/CT in Selecting Thyroid Nodules with Indeterminate Fine-Needle Aspiration Cytology for Surgery. A Systematic Review and a Meta-Analysis.

2019 ◽  
Vol 8 (9) ◽  
pp. 1333 ◽  
Author(s):  
Castellana ◽  
Trimboli ◽  
Piccardo ◽  
Giovanella ◽  
Treglia
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Pet Ct ◽  
18F Fdg ◽  
Needle Aspiration Cytology ◽  
Fdg Pet Ct

Thyroid nodules with indeterminate fine-needle aspiration cytology (FNA) represent a major challenge in clinical practice. We conducted a systematic review and meta-analysis evaluating the ability of hybrid imaging using fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to appropriately select these nodules for surgery. PubMed, CENTRAL, Scopus, and Web of Science were searched until July 2019. Original articles reporting data on the performance of 18F-FDG PET/CT in thyroid nodules with indeterminate FNA were included. Summary operating points including 95% confidence interval values (95% CI) were estimated using a random-effects model. Out of 786 retrieved papers, eight studies evaluating 104 malignant and 327 benign thyroid nodules were included. The pooled positive and negative likelihood ratios (LR+ and LR-) and diagnostic odds ratio (DOR) of 18F-FDG PET/CT were 1.7 (95% CI: 1.4–2.0), 0.4 (95% CI: 0.2–0.7), and 3.5 (95% CI: 1.7–7.1), respectively. No heterogeneity was found for LR+ and DOR. In patients with thyroid nodules with indeterminate FNA, 18F-FDG PET/CT has a moderate ability to correctly discriminate malignant from benign lesions and could represent a reliable option to reduce unnecessary diagnostic surgeries. However, further studies using standardized criteria for interpretation are needed to confirm the reproducibility of these findings.

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