scholarly journals Effect of Time Elapsed since Gadolinium Administration on Atherosclerotic Plaque Enhancement in Clinical Vessel Wall MR Imaging Studies

2019 ◽  
Author(s):  
A. de Havenon ◽  
H.J. Muhina ◽  
D.L. Parker ◽  
J.S. McNally ◽  
M.D. Alexander
Keyword(s):  
Mr Imaging ◽  
Atherosclerotic Plaque ◽  
Vessel Wall ◽  
Imaging Studies ◽  
Gadolinium Administration

Techniques for high-resolution MR imaging of atherosclerotic plaque

1994 ◽  
Vol 4 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Chun Yuan ◽  
Jay S. Tsuruda ◽  
Kirk N. Beach ◽  
Cecil E. Hayes ◽  
Marina S. Ferguson ◽  
...  
Keyword(s):  
High Resolution ◽  
Mr Imaging ◽  
Atherosclerotic Plaque

Intracranial vessel wall MR imaging of an intradural vertebral artery dissection

2020 ◽  
Vol 68 ◽  
pp. 108-110 ◽  
Author(s):  
Kofi-Buaku Atsina ◽  
Aaron Rothstein ◽  
Steven R. Messé ◽  
Jae W. Song
Keyword(s):  
Mr Imaging ◽  
Vertebral Artery ◽  
Vessel Wall ◽  
Vertebral Artery Dissection ◽  
Artery Dissection ◽  
Intracranial Vessel

scholarly journals Black blood vessel wall MRI to identify vulnerable atherosclerotic plaque in a non-stenotic intracranial vertebral artery as a cause of acute ischaemia

2020 ◽  
Vol 6 (4) ◽  
pp. 20200061
Author(s):  
Sundip Dhanvant Udani ◽  
Pervinder Bhogal
Keyword(s):  
Vertebral Artery ◽  
Atherosclerotic Plaque ◽  
Vessel Wall ◽  
Black Blood ◽  
Vulnerable Atherosclerotic Plaque ◽  
Acute Ischaemia ◽  
Neurological Sequelae ◽  
Intracranial Atherosclerotic Disease ◽  
Coronary Syndromes ◽  
Neuroimaging Techniques

Conventional neuroimaging techniques for investigating the cause of stroke are mainly centred on investigating luminal stenosis. The pathophysiology of intracranial atherosclerotic disease (ICAD) and stroke is complex and extends beyond just vessel narrowing. The concept of the vulnerable atherosclerotic plaque, that can result in acute coronary syndromes, has been well described in the cardiac literature 1,2 although this concept is less well accepted among stroke physicians. We describe a case of a 61-year-old male with acute neurological sequelae from a non-stenotic atherosclerotic plaque of the intracranial vertebral artery. This case report describes the additional use of vessel wall MRI techniques to aid the radiologist in identifying such vulnerable lesions and therefore helping to tailor management and prevent further clinical deterioration.

Effectiveness and handling characteristics of a three-layer polymer dura substitute: a prospective multicenter clinical study

2006 ◽  
Vol 105 (6) ◽  
pp. 853-858 ◽  
Author(s):  
A. Martina Messing-Jünger ◽  
Javier Ibáñez ◽  
Fabio Calbucci ◽  
Maurice Choux ◽  
Gabriel Lena ◽  
...  
Keyword(s):  
Clinical Study ◽  
Mr Imaging ◽  
Disease Transmission ◽  
Valsalva Maneuver ◽  
Adhesion Formation ◽  
Type I ◽  
Imaging Studies ◽  
Handling Characteristics ◽  
Csf Leakage ◽  
Multicenter Clinical Study

Object The goal of this study was to assess the effectiveness and handling characteristics of a dura substitute composed of two outer layers of expanded polytetrafluoroethylene (PTFE) and a middle layer consisting of an elastomeric fluoropolymer. Methods In a prospective multicenter study, the dura substitute was implanted using a standard technique in 119 patients undergoing cranial or spinal surgery requiring duraplasty. Intraoperative assessments of the dura patch consisted of testing for cerebrospinal fluid (CSF) leakage employing the Valsalva maneuver and a surgeon’s standard evaluation of the handling characteristics of the device. Postoperative assessments conducted during a mean follow-up time of 15.7 months (range 0.3–45.6 months) consisted of physical examinations, routine computed tomography (CT) or magnetic resonance (MR) imaging studies, and histological studies of any removed dura patches. The mean age of the 119 patients was 40 years (range < 1–81 years). The dura substitute was implanted cranially in 102 patients and spinally in 17. Intraoperative assessment including the Valsalva maneuver led to application of additional sutures in 17 patients. Handling features were rated very good to excellent. Postoperative clinical evaluation resulted in 79 excellent and 18 good results. Imaging studies (MR imaging studies in 69 patients and CT studies in 34 patients) showed no adhesions in 87 patients and minimal adhesions in seven patients (the dura was not visualized in nine patients). Postoperative complications occurred in 12 patients. There were six cases of CSF leakage, three cases of extradural hematoma, one case of arachnoid fibrosis after decompression of a Chiari malformation Type I, and two cases of infection. Eight (7%) of these complications were potentially related to the dura patch. Conclusions In a large, multicenter clinical study of the use of an expanded-PTFE–containing dura substitute, the device was found to be easy to handle and implant. No serious dura patch–related intraoperative adverse events were observed. Postoperatively, there were no major sealing problems or long-term complications. In two cases the patch had to be removed due to fibrosis and infection. The three-layer polymer dura substitute appears to be safe and effective in minimizing CSF leakage and adhesion formation, and its use avoids any risk of prion disease transmission.

Human Carotid Atherosclerotic Plaque Growth Function and Progression Simulation Using Meshless GFD and Statistical Methods Based on Multi-Year In Vivo MRI

2008 ◽  
Author(s):  
Chun Yang ◽  
Joseph D. Petruccelli ◽  
Zhongzhao Teng ◽  
Chun Yuan ◽  
Gador Canton ◽  
...  
Keyword(s):  
Atherosclerotic Plaque ◽  
Wall Thickness ◽  
Vessel Wall ◽  
Plaque Rupture ◽  
Patient Specific ◽  
Tracking Data ◽  
Plaque Progression ◽  
Vessel Wall Thickness ◽  
Plaque Growth

Atherosclerotic plaque rupture and progression have been the focus of intensive investigations in recent years. The mechanisms governing plaque progression and rupture process are not well understood. Using computational models based on patient-specific multi-year in vivo MRI data, our recent results indicated that 18 out of 21 patients studied showed significant negative correlation between plaque progression measured by vessel wall thickness increase (WTI) and plaque wall (structural) stress (PWS) [1]. In this paper, a computational procedure based on meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data was introduced to simulate plaque progression. Participating patients were scanned three times (T1, T2, and T3, at intervals of approximately 18 months) to obtain plaque progression data. Vessel wall thickness (WT) changes were used as the measure for plaque progression. Starting from T2 plaque geometry, plaque progression was simulated by solving the solid model and adjusting wall thickness using plaque growth functions iteratively until time T3 is reached. Numerically simulated plaque progression showed very good agreement with actual plaque geometry at T3 given by MRI data. We believe this is the first time plaque progression simulation results based on multi-year patient-tracking data are reported. Multi-year tracking data and MRI-based progression simulation add time dimension to plaque vulnerability assessment and will improve prediction accuracy.

scholarly journals Pharmacokinetics of Gd(DO3A-Lys) and MR imaging studies in an orthotopic U87MG glioma tumor model

2015 ◽  
Vol 10 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Prashant Chandrasekharan ◽  
Chang-Tong Yang ◽  
Fatima Ali Nasrallah ◽  
Hui Chien Tay ◽  
Kai-Hsiang Chuang ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Tumor Model ◽  
Imaging Studies ◽  
Glioma Tumor
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