scholarly journals Spine Cryoablation: A Multimodality Image-Guided Approach for Tumors Adjacent to Major Neural Elements

2016 ◽  
Vol 37 (12) ◽  
pp. 2396-2399 ◽  
Author(s):  
J.P. Guenette ◽  
K. Tuncali ◽  
N. Himes ◽  
S. Tatli ◽  
T.C. Lee
2021 ◽  
Vol 20 (5) ◽  
pp. E344-E345
Author(s):  
Walid Ibn Essayed ◽  
Kaith K Almefty ◽  
Ossama Al-Mefty

Abstract Recurrent skull base chordomas are challenging lesions. They already had maximum radiation, and in the absence of any effective medical treatment, surgical resection is the only treatment.1,2 Surgery on recurrent previously radiated chordomas, however, carries much higher risk and the likelihood of subtotal resection. Maximizing tumor resection allows longer tumor control.3-5 The Advanced Multimodality Image Guided Operating Suite developed at the Brigham and Women's Hospital, Harvard Medical School, with the support of the National Institutes of Health, provides an optimal environment to manage these tumors. It offers the capability to obtain and integrate multiple modalities during surgery, including magnetic resonance imaging (MRI), positron emission tomography-computed tomography (PET-CT), endoscopy, ultrasound, fluoroscopy, and the ability to perform emergent endovascular procedures.5-7 The patient is a 39-yr-old male, presenting after 19 yr follow-up of a surgical resection and proton beam treatment for a skull base chordoma. He developed progressive ophthalmoplegia due to recurrence of his chordoma at the right petrous apex and cavernous sinus. Preoperative angiography demonstrated narrowing of the petrous segment of the right carotid artery suspect of radiation-induced angiopathy. The presence of radiation-induced angiopathy increases the risk of intraoperative carotid rupture, and the availability of endovascular intervention in the operative suite added favorable preparedness to deal with such complications if they happen. Given the clinical and radiological progression, surgical intervention was carried out through the prior zygomatic approach with the goal of performing maximum resection.8 The patient had an uneventful postoperative course and remained stable until he had a second recurrence 4 yr later. The patient consented to the procedure.


ACS Nano ◽  
2017 ◽  
Vol 11 (2) ◽  
pp. 1509-1519 ◽  
Author(s):  
Yang Liu ◽  
Fang Yang ◽  
Chuxiao Yuan ◽  
Mingxi Li ◽  
Tuantuan Wang ◽  
...  

2017 ◽  
Vol 32 (11) ◽  
pp. 2248-2256 ◽  
Author(s):  
Sri Harsha Tella ◽  
Hayet Amalou ◽  
Bradford J Wood ◽  
Richard Chang ◽  
Clara C Chen ◽  
...  

2016 ◽  
Vol 40 (3) ◽  
pp. E18 ◽  
Author(s):  
Hasan A. Zaidi ◽  
Kenneth De Los Reyes ◽  
Garni Barkhoudarian ◽  
Zachary N. Litvack ◽  
Wenya Linda Bi ◽  
...  

OBJECTIVE Endoscopic skull base surgery has become increasingly popular among the skull base surgery community, with improved illumination and angled visualization potentially improving tumor resection rates. Intraoperative MRI (iMRI) is used to detect residual disease during the course of the resection. This study is an investigation of the utility of 3-T iMRI in combination with transnasal endoscopy with regard to gross-total resection (GTR) of pituitary macroadenomas. METHODS The authors retrospectively reviewed all endoscopic transsphenoidal operations performed in the Advanced Multimodality Image Guided Operating (AMIGO) suite from November 2011 to December 2014. Inclusion criteria were patients harboring presumed pituitary macroadenomas with optic nerve or chiasmal compression and visual loss, operated on by a single surgeon. RESULTS Of the 27 patients who underwent transsphenoidal resection in the AMIGO suite, 20 patients met the inclusion criteria. The endoscope alone, without the use of iMRI, would have correctly predicted extent of resection in 13 (65%) of 20 cases. Gross-total resection was achieved in 12 patients (60%) prior to MRI. Intraoperative MRI helped convert 1 STR and 4 NTRs to GTRs, increasing the number of GTRs from 12 (60%) to 16 (80%). CONCLUSIONS Despite advances in visualization provided by the endoscope, the incidence of residual disease can potentially place the patient at risk for additional surgery. The authors found that iMRI can be useful in detecting unexpected residual tumor. The cost-effectiveness of this tool is yet to be determined.


Theranostics ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 4676-4693 ◽  
Author(s):  
Guochen Ning ◽  
Xinran Zhang ◽  
Qin Zhang ◽  
Zhibiao Wang ◽  
Hongen Liao

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