scholarly journals Clinical Significance of the Champagne Bottle Neck Sign in the Extracranial Carotid Arteries of Patients with Moyamoya Disease

2016 ◽  
Vol 37 (10) ◽  
pp. 1898-1902 ◽  
Author(s):  
C. Yasuda ◽  
S. Arakawa ◽  
T. Shimogawa ◽  
Y. Kanazawa ◽  
T. Sayama ◽  
...  
Nosotchu ◽  
2017 ◽  
Vol 39 (1) ◽  
pp. 6-11
Author(s):  
Shinichi Wada ◽  
Masahiro Yasaka ◽  
Emi Tabata ◽  
Asako Nakamura ◽  
Takahiro Kuwashiro ◽  
...  

2006 ◽  
Vol 25 (12) ◽  
pp. 1547-1552 ◽  
Author(s):  
Masahiro Yasaka ◽  
Toshiyasu Ogata ◽  
Kotaro Yasumori ◽  
Tooru Inoue ◽  
Yasushi Okada

2021 ◽  
Vol 51 (3) ◽  
pp. E5
Author(s):  
Michael S. Rallo ◽  
Omar Akel ◽  
Akhilesh Gurram ◽  
Hai Sun

OBJECTIVE Moyamoya disease (MMD) is an intracranial steno-occlusive pathology characterized by progressive narrowing of proximal large vessels, including the terminal internal carotid arteries (ICAs), middle cerebral arteries, or anterior cerebral arteries. Named for the “puff of smoke” appearance of the anomalous vascularization visualized on cerebral angiography, MMD lacks a well-defined etiology, although significant insights have been made, including the identification of a susceptibility gene, RNF213, in humans with the disease. A limitation to advancing the understanding and treatment of MMD has been the lack of experimental animal models that authentically reflect the clinical pathogenesis. In an effort to analyze characteristics of currently available models and identify strategies for future model generation, the authors performed a scoping review of experimental animal models that have been used to study MMD. METHODS A systematic search of PubMed, Web of Science, and Scopus was performed to identify articles describing animal models used to study MMD. Additional articles were identified via citation searching. Study selection and data extraction were performed by two independent reviewers based on defined inclusion and exclusion criteria. RESULTS A total of 44 articles were included for full-text review. The methods used to generate these animal models were broadly classified as surgical (n = 25, 56.8%), immunological (n = 7, 15.9%), genetic (n = 6, 13.6%), or a combination (n = 6, 13.6%). Surgical models typically involved permanent ligation of one or both of the common carotid arteries or ICAs to produce chronic cerebral hypoperfusion. Genetic models utilized known MMD or cerebrovascular disease-related genes, such as RNF213 or ACTA2, to induce heritable cerebral vasculopathy. Finally, immunological models attempted to induce vasculitis-type pathology by recapitulating the inflammatory milieu thought to underlie MMD. CONCLUSIONS Models generated for MMD have involved three general approaches: surgical, immunological, and genetic. Although each reflects a key aspect of MMD pathogenesis, the failure of any individual model to recapitulate the development, progression, and consequences of the disease underscores the importance of future work in developing a multietiology model.


2013 ◽  
Vol 127 (2) ◽  
pp. 196-199 ◽  
Author(s):  
L-S Tseng ◽  
S-D Luo

AbstractObjective:We describe a rare case of sudden onset of unilateral sensorineural hearing loss occurring as the first symptom of moyamoya disease, which is characterised by progressive stenosis of the intracranial internal carotid arteries and their proximal anterior cerebral arteries and middle cerebral arteries.Method:Case report and review of the world literature regarding moyamoya disease with hearing loss.Results:The reported patient had moyamoya disease that initially presented as sudden, unilateral sensorineural hearing loss. Magnetic resonance imaging showed occlusion of the anterior cerebral, middle cerebral and distal internal carotid arteries bilaterally. The possible mechanism of this patient's sudden sensorineural hearing loss may have been vascular occlusion resulting from thrombotic narrowing or blockage by plaque.Conclusion:The described patient represents the first reported case of sudden onset, unilateral sensorineural hearing loss occurring as the first symptom of moyamoya disease. The possibility of a vascular lesion such as moyamoya disease should be considered in patients with sudden sensorineural hearing loss, especially children, young adults and Asian patients. Due to this disease's poor outcome, early diagnosis and treatment are important to prevent stroke.


2014 ◽  
Vol 6 (2) ◽  
Author(s):  
Sarmad Said ◽  
Chad J. Cooper ◽  
Haider Alkhateeb ◽  
Juan M. Galvis ◽  
German T. Hernandez ◽  
...  

Moyamoya disease was first described in 1957 as <em>hypoplasia of the bilateral internal carotid arteries</em>, the characteristic appearance of the associated network of abnormally dilated collateral vessels on angiography was later likened to something hazy, like a puff of cigarette smoke, which, in Japanese, is <em>moyamoya</em>. This paper describes two cases of moyamoya presentations, including moyamoya disease and moyamoya syndrome. Moyamoya may rarely occur in North American Hispanic patients. The presentation can vary significantly and ranges bwtween fulminant outcome and prolonged survival. Awareness about moyamoya and its different presentations may be beneficial for the patients and can improve the outcome.


Nosotchu ◽  
2018 ◽  
Vol 40 (1) ◽  
pp. 7-10
Author(s):  
Masanori Tomoda ◽  
Masahiro Yasaka ◽  
Yasuyuki Nakanishi ◽  
Goh Takaguchi ◽  
Asako Nakamura ◽  
...  

Retina ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hyo Jin Seong ◽  
Ji Hwan Lee ◽  
Ji Hoe Heo ◽  
Dong Seok Kim ◽  
Yong Bae Kim ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document