scholarly journals Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods

2015 ◽  
Vol 36 (6) ◽  
pp. 1109-1115 ◽  
Author(s):  
S. Valverde ◽  
A. Oliver ◽  
Y. Díez ◽  
M. Cabezas ◽  
J.C. Vilanova ◽  
...  
NeuroImage ◽  
2009 ◽  
Vol 45 (4) ◽  
pp. 1151-1161 ◽  
Author(s):  
Renske de Boer ◽  
Henri A. Vrooman ◽  
Fedde van der Lijn ◽  
Meike W. Vernooij ◽  
M. Arfan Ikram ◽  
...  

2013 ◽  
Author(s):  
Henri Vrooman ◽  
Fedde Van der Lijn ◽  
Wiro Niessen

In this paper we applied one of our regularly used processing pipelines for fully automated brain tissue segmentation. Brain tissue was segmented in cerebrospinal fluid (CSF), gray matter (GM) and white matter (WM). Our algorithms for skull stripping, tissue segmentation and white matter lesion (WML) detection were slightly adapted and applied to twelve data sets within the MRBrainS13 brain tissue segmentation challenge. Skull stripping is performed using non-rigid registration of 5 atlas masks. Our tissue segmentation is based on an automatically trained kNN-classifier. Training samples were obtained by non-rigid registration of 5 manually labeled scans followed by a pruning step in feature space to remove any residual erroneously sampled tissue voxels. The kNN-classification incorporates voxel intensities from a T1-weighted scan and a FLAIR scan. The white matter lesion detection is based on an automatically determined threshold on the FLAIR scan. The application of the algorithms on the data from the MRBrainS13 Challenge showed that our pipeline produces acceptable segmentations. Average resulting Dice scores were 77.86 (CSF), 81.22 (GM), 87.27 (WM), 93.78 (total parenchyma), and 96.26 (all intracranial structures). Total processing time was about 2 hours per subject.


Author(s):  
ZunHyan Rieu ◽  
Donghyeon Kim ◽  
JeeYoung Kim ◽  
Regina EY Kim ◽  
Minho Lee ◽  
...  

White matter hyperintensity (WMH) has been considered the primary biomarker from small-vessel cerebrovascular disease to Alzheimer’s disease (AD) and has been reported for its correlation of brain structural changes. To perform WMH related analysis with brain structure, both T1-weighted (T1w) and (Fluid Attenuated Inversion Recovery(FLAIR) are required. However, in a clinical situation, it is limited to obtain 3D T1w and FLAIR images simultaneously. Also, the most of brain segmentation technique supports 3D T1w only. Therefore, we introduced the semi-supervised learning method that can perform brain segmentation using FLAIR image only. Our method achieved a dice overlap score of 0.86 for brain tissue segmentation on FLAIR, with the relative volume difference between T1w and FLAIR segmentation under 4.8%, which is just as reliable as the segmentation done by its paired T1w image. We believe our semi-supervised learning method has a great potential to be used to other MRI sequences and provide encouragement to people who seek brain tissue segmentation from a non-T1w image.


2014 ◽  
Vol 41 (1) ◽  
pp. 93-101 ◽  
Author(s):  
Sergi Valverde ◽  
Arnau Oliver ◽  
Mariano Cabezas ◽  
Eloy Roura ◽  
Xavier Lladó

NeuroImage ◽  
2010 ◽  
Vol 51 (3) ◽  
pp. 1047-1056 ◽  
Author(s):  
Renske de Boer ◽  
Henri A. Vrooman ◽  
M. Arfan Ikram ◽  
Meike W. Vernooij ◽  
Monique M.B. Breteler ◽  
...  

2021 ◽  
Author(s):  
Yan Zhang ◽  
Yifei Li ◽  
Youyong Kong ◽  
Jiasong Wu ◽  
Jian Yang ◽  
...  

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