scholarly journals 3D Cine Phase-Contrast MRI at 3T in Intracranial Aneurysms Compared with Patient-Specific Computational Fluid Dynamics

2013 ◽  
Vol 34 (9) ◽  
pp. 1785-1791 ◽  
Author(s):  
P. van Ooij ◽  
J.J. Schneiders ◽  
H.A. Marquering ◽  
C.B. Majoie ◽  
E. van Bavel ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Intracranial Aneurysms ◽  
Phase Contrast ◽  
Patient Specific ◽  
Phase Contrast Mri ◽  
Cine Phase Contrast

scholarly journals Porous Media Computational Fluid Dynamics and the Role of the First Coil in the Embolization of Ruptured Intracranial Aneurysms

2021 ◽  
Vol 10 (7) ◽  
pp. 1348
Author(s):  
Karol Wiśniewski ◽  
Bartłomiej Tomasik ◽  
Zbigniew Tyfa ◽  
Piotr Reorowicz ◽  
Ernest Bobeff ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Porous Media ◽  
Packing Density ◽  
Coil Embolization ◽  
Intracranial Aneurysms ◽  
Patient Specific ◽  
Computational Fluid Dynamics Analysis ◽  
Ruptured Intracranial Aneurysms ◽  
Statistical Results

Background: The objective of our project was to identify a late recanalization predictor in ruptured intracranial aneurysms treated with coil embolization. This goal was achieved by means of a statistical analysis followed by a computational fluid dynamics (CFD) with porous media modelling approach. Porous media CFD simulated the hemodynamics within the aneurysmal dome after coiling. Methods: Firstly, a retrospective single center analysis of 66 aneurysmal subarachnoid hemorrhage patients was conducted. The authors assessed morphometric parameters, packing density, first coil volume packing density (1st VPD) and recanalization rate on digital subtraction angiograms (DSA). The effectiveness of initial endovascular treatment was visually determined using the modified Raymond–Roy classification directly after the embolization and in a 6- and 12-month follow-up DSA. In the next step, a comparison between porous media CFD analyses and our statistical results was performed. A geometry used during numerical simulations based on a patient-specific anatomy, where the aneurysm dome was modelled as a separate, porous domain. To evaluate hemodynamic changes, CFD was utilized for a control case (without any porosity) and for a wide range of porosities that resembled 1–30% of VPD. Numerical analyses were performed in Ansys CFX solver. Results: A multivariate analysis showed that 1st VPD affected the late recanalization rate (p < 0.001). Its value was significantly greater in all patients without recanalization (p < 0.001). Receiver operating characteristic curves governed by the univariate analysis showed that the model for late recanalization prediction based on 1st VPD (AUC 0.94 (95%CI: 0.86–1.00) is the most important predictor of late recanalization (p < 0.001). A cut-off point of 10.56% (sensitivity—0.722; specificity—0.979) was confirmed as optimal in a computational fluid dynamics analysis. The CFD results indicate that pressure at the aneurysm wall and residual flow volume (blood volume with mean fluid velocity > 0.01 m/s) within the aneurysmal dome tended to asymptotically decrease when VPD exceeded 10%. Conclusions: High 1st VPD decreases the late recanalization rate in ruptured intracranial aneurysms treated with coil embolization (according to our statistical results > 10.56%). We present an easy intraoperatively calculable predictor which has the potential to be used in clinical practice as a tip to improve clinical outcomes.

Comparative Computational Fluid Dynamics and Experimental Phase-Contrast MRI: Evaluations of In-Stent Restenosis

2004 ◽  
Author(s):  
Andrea D. Holton ◽  
Brigitta C. Brott ◽  
Edward G. Walsh ◽  
Ramakrishna Venugopalan ◽  
Alan M. Shih ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Phase Contrast ◽  
Imaging Modality ◽  
Metal Stents ◽  
Phase Contrast Mri ◽  
Peripheral Vasculature ◽  
Susceptibility Artifacts ◽  
Stent Restenosis ◽  
In Stent Restenosis

While angiography and other translesional catheter-based assessments of stented peripheral vasculature are currently used in clinical applications, a quantitative non-invasive imaging modality would improve the treatment of intermediate levels of in-stent restenosis (ISR). The use of magnetic resonance imaging (MRI), in metal stents has been limited due to magnetic susceptibility artifacts and radiofrequency shielding effects. However, MRI compatible materials such as nickel-titanium alloys used in stents have shown superior lumen visibility. In this study, we used phase contrast MRI in a flow phantom of three different geometries of stenosis: a) 90% axisymmetric, b) 75% axisymmetric and c) 50% asymmetric. The velocity distribution was obtained at 3 different locations inside the stent. This was compared with an equivalent computational fluid dynamics (CFD) model of the same stenotic geometries.

Quantitative Hemodynamic Comparison of Velocity Values From Computational Fluid Dynamics and Phase-Contrast MRI in an In-Vitro Aneurysm Model

2012 ◽  
Author(s):  
Stephanie M. George ◽  
Amos Cao ◽  
Don P. Giddens ◽  
John N. Oshinski ◽  
Frank C. Tong
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Phase Contrast ◽  
Poor Correlation ◽  
Phase Contrast Mri ◽  
General Acceptance ◽  
Contrast Magnetic Resonance ◽  
Measured Flow ◽  
Aneurysm Model

Intracranial aneurysms affect thousands of people every year, therefore the ability to monitor their growth or predict their rupture would be invaluable for planning treatment. One proposed method to address this issue of predicting rupture is to use computational fluid dynamics (CFD) based on phase contrast magnetic resonance (PC-MR). CFD and PCMR have been used to understand some of the fundamental conditions of cerebrovascular flow. While there has been general acceptance of the validity of CFD, some research suggests that there can be poor correlation between CFD flow calculations and directly measured flow (1). Previous research has qualitatively compared CFD to PC-MR and demonstrated similar pathlines (2). To the authors’ knowledge a systematic quantitative comparison has not been preformed. Therefore the purpose of this work is to quantitatively compare velocity data from phase-contrast MRI measurements and from a CFD model derived from MRI geometry and flow boundary conditions in an in-vitro aneurysm model.

scholarly journals Velocity Measurement in Carotid Artery: Quantitative Comparison of Time-Resolved 3D Phase-Contrast MRI and Image-based Computational Fluid Dynamics

2015 ◽  
Vol 12 (4) ◽  
Author(s):  
Ali Sarrami-Foroushani ◽  
Mohsen Nasr Esfahany ◽  
Abbas Nasiraei Moghaddam ◽  
Hamidreza Saligheh Rad ◽  
Kavous Firouznia ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Carotid Artery ◽  
Velocity Measurement ◽  
Phase Contrast ◽  
Quantitative Comparison ◽  
Phase Contrast Mri ◽  
Time Resolved
Sign in / Sign up

Export Citation Format

Share Document