scholarly journals Fungal multisinusitis with intracranial extension

1970 ◽  
Vol 39 (136) ◽  
pp. 354-356
Author(s):  
N Thapa ◽  
B K Sinha ◽  
RCM Amatya ◽  
P Shrivastav ◽  
B Pradhan ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Ct Scan ◽  
Paranasal Sinuses ◽  
Intracranial Extension ◽  
Healthy Patient ◽  
Nose And Paranasal Sinuses

Aspergillosis is the commonest fungal infection of nose and paranasal sinuses. Itsinvasive form is rare in a healthy patient. A case of fungal multisinusitis with intracranialextension with characteristic computerized tomographic finding is reported.Key Words: Aspergillosis, intracranial extension, CT scan,external frontoethmoidectomy.

scholarly journals Frontal sinus mucopyelocele with intracranial and intraorbital extension

1970 ◽  
Vol 3 (1) ◽  
pp. 91-92 ◽  
Author(s):  
S Gupta ◽  
R Goyal ◽  
M Shahi
Keyword(s):  
Ct Scan ◽  
Paranasal Sinuses ◽  
Frontal Sinus ◽  
Visual Loss ◽  
Early Recognition ◽  
Surgical Excision ◽  
Intracranial Extension ◽  
External Approach ◽  
Intracranial Complications ◽  
Symptoms And Signs

This case is related to a 52-year-old lady with proptosis, diplopia and diminution of vision due to a mass lesion in upper medial quadrant of the orbit. CT scan revealed a well defined mass in basi-frontal area with intra-orbital and intracranial extension. On exploring it was found to be mucopyocele of the frontal sinus. Surgical excision was done by external approach. The symptoms and signs resolved completely within a week. Frontal sinus mucopyoceles are benign and curable. Early recognition and management of them is of paramount importance because they can expand and cause local, orbital or intracranial complications. Keywords: Mucocele; mucopyocele; paranasal sinuses; visual loss; proptosis  DOI: 10.3126/nepjoph.v3i1.4287Nepal J Ophthalmol 2011;3(5):91-92

scholarly journals Coinfection byAspergillusand Zygomycetes Species in a Case of Acute Rhinosinusitis

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Dhara Vaidya ◽  
Parul Shah
Keyword(s):  
Aspergillus Flavus ◽  
Paranasal Sinuses ◽  
Histopathological Examination ◽  
Rapid Identification ◽  
Intracranial Extension ◽  
Acute Rhinosinusitis ◽  
History Of ◽  
Nose And Paranasal Sinuses ◽  
Endoscopic Debridement ◽  
Mycotic Infections

Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection byAspergillusandRhizopussp. involving nose, paranasal sinuses, orbit, and brain in a 68-year-old known hypertensive male. He was presented to ENT OPD with history of fever and intermittent headache since fifteen days along with history of right-sided nasal obstruction and proptosis since seven days. CT scan of brain and paranasal sinuses showed findings of pansinusitis with cellulitic changes in right orbit. MRI confirmed the same along with features of intracranial extension with focal meningitis in right frontotemporal region. Laboratory parameters did not conclude much except for leucocytosis and hyponatremia. Patient was taken for endoscopic debridement from nose and paranasal sinuses, and tissue was sent for microbiological and histopathological examination. Minced tissue was processed, and after 48 hrs of incubation two types of growth were identified, one was yellowish, granular, and powdery consistent withAspergillussp., and another was cottony and woolly consistent withRhizopussp. LCB mount confirmed presence ofAspergillus flavusandRhizopus arrhizus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good.

scholarly journals Rhino-orbital mucormycosis in COVID-19 patients—a new threat?

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Sandeep Singh Awal ◽  
Som Subhro Biswas ◽  
Sampreet Kaur Awal
Keyword(s):  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Paranasal Sinuses ◽  
Correct Diagnosis ◽  
Antifungal Drugs ◽  
Intracranial Extension ◽  
Imaging Findings ◽  
Case Presentation ◽  
Mortality And Morbidity ◽  
History Of

Abstract Background Coronavirus disease 2019 (COVID-19) is known to be associated with a myriad of viral, fungal, and bacterial co-infections. Rhino-orbital mucormycosis is a rare angio-invasive fungal infection which has shown a rising trend in the setting of COVID-19. Case presentation We describe the imaging findings in 3 cases of rhino-orbital mucormycosis in patients with history of COVID-19. All cases had varying involvement of paranasal sinuses extending into the orbital compartment while case 3 had intracranial extension of infection. Conclusions Rhino-orbital mucormycosis can have aggressive necrosis of the involved paranasal sinuses and orbits with or without cerebral extension. Hence, the correct diagnosis is imperative as prompt antifungal drugs and surgical debridement can significantly reduce mortality and morbidity.

scholarly journals Quality of life in patients with fungal infection of nose and paranasal sinuses: A study from North India

2017 ◽  
Vol 33 (4) ◽  
pp. 346
Author(s):  
Tanuja Kaushal ◽  
Nitin Gupta ◽  
Rushi ◽  
Surinder Singhal ◽  
Jagdish Chander ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Fungal Infection ◽  
Paranasal Sinuses ◽  
North India ◽  
Nose And Paranasal Sinuses

scholarly journals Rhinocerebral Mycosis: Combined Modality Protocol

2009 ◽  
Vol 1 (1) ◽  
pp. 49-54
Author(s):  
Gopika Kalsotra
Keyword(s):  
Fungal Infection ◽  
Nasal Cavity ◽  
Antifungal Therapy ◽  
Invasive Fungal Infection ◽  
Surgical Approach ◽  
Paranasal Sinuses ◽  
Surgical Debridement ◽  
High Rate ◽  
Intracranial Extension ◽  
The Brain

Abstract Rhinocerebral mycosis is an invasive fungal infection which occurs primarily in the paranasal sinuses and progresses to involve the brain and/or the orbit. It is commonly seen in immunocompromised individuals and can be most effectively treated if diagnosed early, when it is limited to the nasal cavity and the paranasal sinuses. Even though it is acceptable that surgical debridement in combination with antifungal therapy can lead to high rate of cure, the surgical approach for intracranial extension is still a subject of debate. Twenty-four cases of rhinocerebral mycosis managed at our institute are discussed, regarding presenting complaints and management.

scholarly journals Clinical study of fungal sinusitis

2018 ◽  
Vol 4 (5) ◽  
pp. 1307 ◽  
Author(s):  
Jyotika Waghray
Keyword(s):  
Fungal Infection ◽  
Aspergillus Fumigatus ◽  
Paranasal Sinuses ◽  
Bacterial Flora ◽  
Nasal Discharge ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Facial Swelling ◽  
Nose And Paranasal Sinuses ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Fungal sinusitis is a distinct clinical entity characterized by inflammation of the sinus mucosa caused by fungal infection like aspergillus (fumigatus, niger, flavus), mucormycosis, candida (albicans), scedosporium, pencillium. Mostly immunocompromised patients, farmers, garbage cleaners, and patients on prolonged nasal sprays are affected. There are different types of fungal sinusitis: fungal mycetoma, allergic fungal, chronic indolent and fulminant sinusitis having symptoms like chronic headache and facial swelling with visual impairment. Patients have thick purulent nasal discharge, nasal obstruction, epistaxis, cheek swelling and may be polyposis. Resident bacterial flora probably inhibits colonization by fungi through a number of mechanisms. Thus antimicrobial therapy predisposes to both the overgrowth of normal fungal flora, e.g., Candida species, and growth of opportunists like Aspergillus<sup>1</sup>. Allergic fungal rhinosinusitis is the most common entity. Aspergillosis is the most common fungal infection. Of these aspergillus fumigatus is the most common fungal pathogen. Maxillary sinuses are commonly involved.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study carried out at department of otorhinolaryngology at Kunal Institute of Medical Specialities Pvt Ltd. Evaluation by proper history taking and clinical examination after which the patient is selected for nasal swab, culture and sensitivity. Plain x-ray nose and paranasal sinuses. CT scans nose and paranasal sinuses. Diagnostic nasal endoscopy.  </p><p class="abstract"><strong>Results:</strong> Allergic fungal sinusitis was the most common entity found with aspergillosis being the most common organism.</p><p><strong>Conclusions:</strong> Allergic fungal sinusitis was most commonly found in the age group of 20 to 29 years with maxillary sinus most commonly affected. </p>

scholarly journals Study on management of fungal infections of nose and parnasal sinuses

2018 ◽  
Vol 5 (1) ◽  
pp. 45
Author(s):  
Prasad A. Kelkar ◽  
Jyoti V. Hirekerur
Keyword(s):  
Fungal Infection ◽  
Paranasal Sinuses ◽  
Antifungal Agents ◽  
Opportunistic Infections ◽  
Fungal Infections ◽  
Detailed Examination ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Adequate Dose ◽  
Nose And Paranasal Sinuses

<p class="abstract"><strong>Background:</strong> From last few years, the fungal infection has been increasing due to greatly enhanced international traffic and as opportunistic infections in consequence of use of powerful cytotoxic drugs. The disease invariably occurs in diabetics, usually with ketoacidosis, immune compromised patients. Hence, we planned to undertake the present study to evaluate a standard method of management of fungal infections of nose and paranasal sinuses.</p><p class="abstract"><strong>Methods:</strong> A detailed examination of the nose and pranasal sinuses was carried out in the department of ENT. The patients were continuously monitored with pulse oximetry and ECG monitor. In all patients, nasal endoscopy was performed.  </p><p class="abstract"><strong>Results:</strong> In this study, fungal infections of the nose and paranasal sinuses were found to be common between 20 and 50 years of age. Aspergillosis was the commonest sinonasal fungal infection followed by allergic fungal sinusitis, rhinosporidiosis and mucormycosis.</p><p class="abstract"><strong>Conclusions:</strong> Early detection, proper and adequate dose of antifungal agents, timely surgical intervention in the form of debridement and sphenoethmoidectomy and orbital exenteration improve the survival rate in the disease of sinonasal fungal infections.</p><p> </p>

scholarly journals Fulminant Mucormycosis Involving Paranasal Sinuses: A Rare Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Komali Garlapati ◽  
Sunanda Chavva ◽  
Rahul Marshal Vaddeswarupu ◽  
Jyotsna Surampudi
Keyword(s):  
Fungal Infection ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Maxillary Antrum ◽  
Fungal Spores ◽  
Direct Invasion ◽  
Susceptible Patient ◽  
Rare Case Report ◽  
Nose And Paranasal Sinuses ◽  
Diabetic Individual

Mucormycosis is an opportunistic fulminant fungal infection, which has the ability to cause significant morbidity and frequently mortality in the susceptible patient. Common predisposing factors include diabetes mellitus and immunosuppression. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The fungus invades the arteries leading to thrombosis that subsequently causes necrosis of the tissue. The infection can spread to orbital and intracranial structures either by direct invasion or through the blood vessels. Here we describe a case of mucormycosis of maxillary antrum extending to ethmoidal and frontal sinus and also causing necrosis of left maxilla in an uncontrolled diabetic individual to emphasize early diagnosis and treatment of this fatal fungal infection.

scholarly journals Correlation of anatomical variations in chronic sinusitis with diagnostic nasal endoscopy and CT scan of paranasal sinuses: an observational study

2018 ◽  
Vol 5 (1) ◽  
pp. 41
Author(s):  
G. Ramesh Babu ◽  
G. Ravi Kumar ◽  
V. Krishna Chaitanya
Keyword(s):  
Ct Scan ◽  
Paranasal Sinuses ◽  
Middle Turbinate ◽  
Lateral Wall ◽  
Anatomical Variations ◽  
Normal Function ◽  
Sinus Surgery ◽  
Nasal Endoscopy ◽  
Common Finding ◽  
Nose And Paranasal Sinuses

<p class="abstract"><strong>Background:</strong> Drainage and ventilation of paranasal sinuses are important for normal function which depends on effective mucociliary clearance. In present study we tried to emphasize variations in lateral wall of nose and clinical features leading to nose and paranasal sinus disease using diagnostic nasal endoscopy and variations in CT scan of paranasal sinuses. The objectives of the study are to observe various anatomical variations in nose and paranasal sinuses and their clinical presentation using diagnostic nasal endoscopy and CT scan of paranasal sinuses and to compare various anatomical variations in nose and paranasal sinuses.</p><p class="abstract"><strong>Methods: </strong>Present study included 54 patients presenting in Department of ENT, Head and Neck Surgery, during February 2015 to February 2017.   </p><p class="abstract"><strong>Results:</strong> Diagnostic nasal endoscopy findings reveal that most common finding was polypoidal changes in nasal mucosa in 36 (66.67%) of patients, followed by mucopurulent discharge in 26 (48.14%), postnasal discharge in 20(37.03%) and 4 (7.40%) patients showed prominent agger nasi cell. CT scan of paranasal sinuses revealed multiple sinus involvement in 41 (75.92%) of patients with partial involvement of sinuses. Complete sinus opacification with pan sinusitis was observed in 9 (16.67%), blockade at osteomeatal complex was observed in 46 (85.18%), paradoxical middle turbinate was observed in 5 (9.25%), Concha bullosa was observed in 12 (22.23%) of patients.</p><p class="abstract"><strong>Conclusions:</strong> Each variation have an anatomic and surgical significance, hence each and every case should be individually studied in detail before undergoing functional endoscopic sinus surgery to maximize patient benefit and to prevent unnecessary complications. Diagnostic nasal endoscopic examination is clinical guide to evaluate disease.</p>

scholarly journals Correlation Between the Opacification Degree of Paranasal Sinuses on CT, Clinical Symptoms and Anatomical Variations of the Nose and Paranasal Sinuses in Patients with Chronic Rhinosinusitis

2021 ◽  
Author(s):  
Mahdi Niknami ◽  
Elham Emami ◽  
Abdolhosein Mozaffari ◽  
Hashem Sharifian ◽  
Sanaz Safari
Keyword(s):  
Ct Scan ◽  
Chronic Rhinosinusitis ◽  
Nasal Obstruction ◽  
Paranasal Sinuses ◽  
Clinical Symptoms ◽  
Anatomical Variation ◽  
Anatomical Variations ◽  
Clinical Findings ◽  
Nose And Paranasal Sinuses ◽  
Ethmoid Sinuses

Objectives: This study aimed to evaluate the correlation between the opacification degree of the paranasal sinuses on computed tomography (CT) with clinical symptoms, and anatomical variations of the nose and paranasal sinuses in patients with chronic rhinosinusitis (CRS). Materials and Methods: This descriptive prospective study evaluated 100 patients (60 males and 40 females), who were diagnosed with CRS by ENT specialists according to the clinical findings, and were scheduled for a CT scan. The patients were requested to express the severity of their symptoms using a visual analog scale. The CT scans of the paranasal sinuses were assessed for the presence of anatomical variations and scored using the modified Lund-Mackay scoring system for the opacification degree of each sinus. The correlations between the anatomical variations and sinusitis, and also between the severity of symptoms/disease severity and CT scores were statistically analyzed. P<0.05 was considered statistically significant. Results: The most common symptoms were purulent (discolored) nasal drainage and nasal obstruction. Septal deviation was the most common anatomical variation. The maxillary and anterior ethmoid sinuses were the most commonly involved areas. The Spearman’s correlation coefficient showed a significant correlation between the sinus involvement and some of the evaluated symptoms, as well as certain types of anatomical variations (P<0.05). Conclusion: Some specific anatomical variations of the paranasal sinuses may predispose them to sinusitis. The CT scan score can predict the severity of many symptoms such as purulent (discolored) nasal drainage, nasal obstruction, hyposmia/anosmia, halitosis, cough, and fatigue, among the other symptoms of CRS.

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