scholarly journals Fulminant Mucormycosis Involving Paranasal Sinuses: A Rare Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Komali Garlapati ◽  
Sunanda Chavva ◽  
Rahul Marshal Vaddeswarupu ◽  
Jyotsna Surampudi

Mucormycosis is an opportunistic fulminant fungal infection, which has the ability to cause significant morbidity and frequently mortality in the susceptible patient. Common predisposing factors include diabetes mellitus and immunosuppression. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The fungus invades the arteries leading to thrombosis that subsequently causes necrosis of the tissue. The infection can spread to orbital and intracranial structures either by direct invasion or through the blood vessels. Here we describe a case of mucormycosis of maxillary antrum extending to ethmoidal and frontal sinus and also causing necrosis of left maxilla in an uncontrolled diabetic individual to emphasize early diagnosis and treatment of this fatal fungal infection.

Author(s):  
Jyoti Singh ◽  
Jai Lal Davessar ◽  
Sumit Prinja ◽  
Nitin Arora

<p class="abstract">Angiosarcomas are the malignant neoplasias of vascular phenotype whose constituent tumor cells have endothelial features. They account for less than 1% of all sinonasal tract malignancies. A case of 65 year old male with a 6 months history of spontaneous epistaxis and a nasal mass lesion presented to the OPD. On physical examination, a polypoidal purplish tumor of 6 × 5 cm was identified. A NCCT scan of nose and paranasal sinuses showed a nonenhanced tumor in the left nostril in maxillary, ethmoid, sphenoid and frontal sinus. An excisional biopsy revealed a poorly differentiated angiosarcoma. Surgical removal of the lesion was advised which was refused by the patient.</p><p class="abstract">Patient was put on the radiation therapy. Angiosarcoma of the nose and paranasal sinuses is an extremely rare tumor. Recurrences are common due to incomplete excision or mutiflocality.</p>


2012 ◽  
Vol 1 (2) ◽  
pp. 73-75 ◽  
Author(s):  
Prashant Khatiwada ◽  
Aditi Giri ◽  
Prasana Khatiwoda

Mucormycosis is an opportunistic fulminant fungal infection, which mainly infects immunocompromised patients. Infection with mucormycosis can cause devastating rhino-orbital-cerebral and pulmonary infection with an extremely poor prognosis. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. We report a case of mucormycosis in an uncontrolled diabetic patient to emphasize early diagnosis of this potentially fatal fungal infection. Rhino-orbitalcerebral mucormycosis is the most common manifestation in patients with diabetes mellitus. We also review the current concepts in management of mucormycosis. Mucormycosis remains difficult to treat and requires a multifaceted approach involving elimination of predisposing factors, surgical debridement, and anti-fungal therapy. Lipid formulations of Amphotericin B are the treatments of choice. DOI: http://dx.doi.org/10.3126/jaim.v1i2.6531 Journal of Advances in Internal Medicine 2012;01(02):73-75


2021 ◽  
pp. 72-76
Author(s):  
Srikanth Kasaraneni ◽  
S. Ravi Raja Kumar ◽  
D. Vamsi Krishna Reddy ◽  
Sowmya Mantha ◽  
Soundarya Mopidevi ◽  
...  

Fungi of the order Mucorales causes an invasive and potentially lethal infection known as mucormycosis. It is a devastating disease in patients with poorly controlled diabetes mellitus and immunocompromised conditions. The infection either begins in the nose and paranasal sinuses due to inhalation of fungal spores or an ulcer or extraction of teeth aids as portal of entry. The infection can also spread to orbital and intracranial structures either through direct invasion or the blood vessels. It is an aggressive infection that needs to be addressed promptly to prevent fatal consequences. We report a case of maxillary necrosis in an uncontrolled diabetic patient due to mucormycois to emphasize importance early diagnosis and treatment of this potentially fatal fungal infection. We briey review the literature of rhinocerebral mucormycosis in terms of its pathogenesis, portal of entry and predisposing factors, incidence and forms, clinical features, diagnosis, differential diagnosis and various management options.


2020 ◽  
Vol 24 (4) ◽  
pp. 28
Author(s):  
SarahAbdul Wahed ◽  
Katakam Pradeepthi ◽  
MadalaJaya Kiran ◽  
GuttikondaVenkateswara Rao

2020 ◽  
Vol 05 (05) ◽  
pp. 271-272
Author(s):  
Dr. Sunita Singh ◽  
Dr. Bharti Sharma ◽  
Dr. Ritesh Kumar Sheorain ◽  
Dr. Tripti Jain ◽  
Dr. Pooja Dhamija ◽  
...  

2015 ◽  
Vol 8 (3) ◽  
pp. 124-126
Author(s):  
Ankita Joshi ◽  
Chinmay Sundarray ◽  
Krishna Arpita Sahoo

ABSTRACT Paranasal sinus anatomical anomalies with unknown etiology are common. Paranasal sinus-related diseases are associated with so high rate of morbidities, it becomes essential to identify the structure and pathophysiology of the paranasal sinuses. Computed tomography (CT) is a valuable tool in displaying its anatomy, any anatomic variations and diseases. As paranasal sinus development is a complex and long-lasting process, there are great structural variations between individuals. Maxillary and/or frontal sinus aplasia or hypoplasia are more common than the other types. Several degrees and combinations of aplasias and hypoplasias have been reported; however, there is only two case of total paranasal sinus aplasia in the literature. Here, we present the third case of total paranasal sinus aplasia, and the first ever case reported from India. How to cite this article Joshi A, Sundarray C, Sahoo KA. Bilateral Total Aplasia of Paranasal Sinuses: A Rare Case Report. Clin Rhinol An Int J 2015;8(3):124-126.


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