scholarly journals Doctor's Role in Early Detection of Diabetic Retinopathy and Prevention of Blindness from its Complications

2005 ◽  
Vol 44 (157) ◽  
Author(s):  
Sudesh Subedi ◽  
K U Subedi ◽  
B P Badhu
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Early Detection ◽  
Type I Diabetes ◽  
Developed Countries ◽  
Type I ◽  
Rapid Urbanization ◽  
Chronic Hyperglycemia ◽  
Working Age ◽  
Diabetic Population

Diabetic retinopathy (DR) is a microangiopathy, which is caused by chronic hyperglycemia, affecting theretinal arterioles, capillaries and venules, complications of which lead to incurable blindness.Approximately 10% of the diabetic population has type I diabetes mellitus (DM) which is diagnosed beforethe age of 30 years1 and rest is type II which is diagnosed after the age of 30 years. In UK 2% generalpopulation is affected by DM. In developed countries, diabetic retinopathy is an important and leadingcause of blindness in working age group where as in developing western countries this figure occupy 12% ofthe blindness.In developing countries like Nepal, cataract still remains a main cause of blindness and diabetes is notconsidered as a major problem. However due to a rapid urbanization and modernization of population,diabetes mellitus is becoming an endemic disease and bringing a new challenge in blindness reduction program.Key Words: Early detection of DR, Classification of DR, Complications, Prevention of blindness.

scholarly journals The Benefits of Flavonoids in Diabetic Retinopathy

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3169 ◽  
Author(s):  
Ana L. Matos ◽  
Diogo F. Bruno ◽  
António F. Ambrósio ◽  
Paulo F. Santos
Keyword(s):  
Diabetic Retinopathy ◽  
Fruits And Vegetables ◽  
Type I Diabetes ◽  
Developed Countries ◽  
Type I ◽  
Cellular Effects ◽  
Diabetic Retina ◽  
Working Age ◽  
Type Ii Diabetics ◽  
Almost All

Diabetic retinopathy (DR), one of the most common complications of diabetes, is the leading cause of legal blindness among adults of working age in developed countries. After 20 years of diabetes, almost all patients suffering from type I diabetes mellitus and about 60% of type II diabetics have DR. Several studies have tried to identify drugs and therapies to treat DR though little attention has been given to flavonoids, one type of polyphenols, which can be found in high levels mainly in fruits and vegetables, but also in other foods such as grains, cocoa, green tea or even in red wine. Flavonoids have anti-inflammatory, antioxidant and antiviral effects. Since it is known that diabetes induces oxidative stress and inflammation in the retina leading to neuronal death in the early stages of the disease, the use of these compounds can prove to be beneficial in the prevention or treatment of DR. In this review, we summarize the molecular and cellular effects of flavonoids in the diabetic retina.

scholarly journals Relationship between lipid profiles with carotid intima--media thickness in children with type I diabetes mellitus

2016 ◽  
Vol 48 (3) ◽  
pp. 147
Author(s):  
Rubiana Sukardi ◽  
Bambang Madiyono ◽  
Sudigdo Sastroasmoro ◽  
Jose RL Batubara
Keyword(s):  
Diabetes Mellitus ◽  
Type I Diabetes ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Lipid Profiles ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Duration Of Diabetes ◽  
Media Thickness ◽  
Chronic Hyperglycemia

Background The major cause of morbidity and mortality inpatients with type I diabetes mellitus is premature and extensiveartherosclerosis. Carotid intima-media thickness (IMT) isassociated with cardivascular risk factors and has been used as amarker of early artherosclerosis process.Objective To determine IMT of carotid artery and its relationshipwith duration of diabetes, lipid profiles, and mean HbA 1 level.Methods A cross-sectional study was conducted on patientswith type 1 DM at the Department of Child Health CiptoMangunkusumo Hospital. Ultrasound B-mode imaging wasperformed to measure the IMT. Age-matched non-diabteticsubjects served as controls. Statistical significant was assumedat P<O.S.Results The mean IMT values of type I DM patients aged < 12years, 12-18 years, 18+ years were 0.44 (SD 0.03) mm; 0.46(SD 0.01) mm; 0.51 (SD 0.01) mm, respectively, which weresignificantly greater than those of age-matched non-diabeticsubjects which were 0.39 (SD 0.01), 0.41 (SD 0.01) mm, 0.46(SD 0.01) mm, respectively. Patients with type I DM had ahigher apolipoprotein-Band HDL cholesterol levels than in non-diabetic subjects. Multiple regression analysis showed that therewas no relationship between total cholesterol, cholesterol LDL,chronic hyperglycemia (HbA 1) and IMT. However, IMT in typeI diabetes was linearly related with duration of diabetes .Conclusion Type I DM patients have greater IMT and highermean apolipoprotein B. There is a strong correlation betweenIMT and duration of diabetes.

Bilateral pulmonary hydathidic cyst with fatal outlet: a case report

2021 ◽  
Vol 5 (1) ◽  
pp. 11-13
Author(s):  
Junior Julio Zapata Choque
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Case Report ◽  
Type I Diabetes ◽  
Signs And Symptoms ◽  
Mass Effect ◽  
Type I ◽  
Insulin Dependent ◽  
Dependent Patient ◽  
Patient Diabetes

Hydatidosis is a parasitic zoonosis caused by Echinococcus Granulosus, its life cycle includes dogs, sheep and others; liver involvement is the most frequent (65%-75%), followed by the lung (10%-25%), in Peru the pulmonary location is 60%. Its signs and symptoms are produced by the mass effect, its superinfection or anaphylactic reactions secondary to its rupture. We present the case of a 24-year-old insulin-dependent patient with type I diabetes mellitus, hypertension and diabetic retinopathy with bilateral pulmonary hydatidosis. A cystectomy was performed without complications and a lobectomy that was complicated with admission to the ICU until the death of the patient. Diabetes mellitus causes a state of immunosuppression which caused the advanced state of the patient's parasitosis, as well as being related to multiple intra- and postoperative complications and even leading to the death of the patient.

Circulating Lipid Levels and Severity of Diabetic Retinopathy in Type I Diabetes mellitus

1987 ◽  
Vol 19 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Roberto Miccoli ◽  
Giorgio Odello ◽  
Ottavio Giampietro ◽  
Piero Marchetti ◽  
Renza Cristofani ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Type I Diabetes ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Lipid Levels

Effects of long-term optimization and short-term deterioration of glycemic control on glucose counterregulation in type I diabetes mellitus

Diabetes ◽  
1984 ◽  
Vol 33 (4) ◽  
pp. 394-400 ◽  
Author(s):  
G. Bolli ◽  
P. De Feo ◽  
S. De Cosmo ◽  
G. Perriello ◽  
G. Angeletti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Type I Diabetes ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Short Term

Competitive insulin autoantibody assay. Prospective evaluation of subjects at high risk for development of type I diabetes mellitus

Diabetes ◽  
1987 ◽  
Vol 36 (11) ◽  
pp. 1286-1291 ◽  
Author(s):  
P. Vardi ◽  
S. A. Dib ◽  
M. Tuttleman ◽  
J. E. Connelly ◽  
M. Grinbergs ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
High Risk ◽  
Type I Diabetes ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Prospective Evaluation ◽  
Insulin Autoantibody
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