scholarly journals Interrelationship between Diabetes and Periodontitis- A Review

2011 ◽  
Vol 51 (183) ◽  
Author(s):  
S Pradhan ◽  
K Goel
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Systemic Disease ◽  
The Other ◽  
Low Grade ◽  
Oral Infections ◽  
Periodontal Infection ◽  
The Individual ◽  
Length Of Life

Evidence for the link between periodontal disease and several systemic diseases is growing rapidly. Diabetes mellitus is a systemic disease with several major complications affecting both the quality and length of life causing morbidity and mortality. Periodontitis, one of these complications, is a chronic infection associated with substantial morbidity in the form of tooth loss and that affects the quality of life directly. The association between diabetes and inflammatory periodontal disease has been studied extensively. The relationship between these two conditions appears bidirectional. The presence of one condition tends to promote the other and the meticulous management of either may assist treatment of the other. It also provides a perfect example of a cyclical association, whereby a systemic disease predisposes the individual to oral infections, and once the oral infection is established, it exacerbates the systemic disease. This review focuses to explain the interrelationship between the two based on information in the literature and the potential common immunoregulatory connections involved, exploring the mechanisms through which periodontal infection can contribute to the low-grade general inflammation associated with diabetes. Keywords: Diabetes mellitus; inflammation; insulin resistance; periodontitis.

scholarly journals Carotenoids and Periodontal Infection

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 269
Author(s):  
Koji Naruishi
Keyword(s):  
Diabetes Mellitus ◽  
Infectious Disease ◽  
Blood Stream ◽  
The Other ◽  
Low Grade ◽  
Gram Negative Bacteria ◽  
Systemic Diseases ◽  
Gram Negative ◽  
Periodontal Infection ◽  
Novel Strategy

Periodontitis is a polymicrobial infectious disease that leads to inflammation of the gingiva, resulting in teeth loss by various causes such as inflammation-mediated bone resorption. Recently, many investigators have reported that the periodontitis resulting from persistent low-grade infection of Gram-negative bacteria such as Porphyromonas gingivalis (Pg) is associated with increased atherosclerosis, diabetes mellitus, and other systemic diseases through blood stream. On the other hand, carotenoids belong among phytochemicals that are responsible for different colors of the foods. It is important to examine whether carotenoids are effective to the inhibition of periodontal infection/inflammation cascades. This review summarizes the advanced state of knowledge about suppression of periodontal infection by several carotenoids. A series of findings suggest that carotenoids intake may provide novel strategy for periodontitis treatment, although further study will be needed.

The Science of Individuality and Tailored M-Health Communication

2022 ◽  
pp. 635-656
Author(s):  
Anastasius S. Moumtzoglou
Keyword(s):  
Quality Of Life ◽  
Health Communication ◽  
Communication Technology ◽  
The Other ◽  
Health Technologies ◽  
Other Hand ◽  
Tailored Communication ◽  
The Individual ◽  
Tailored Communications

The era of the science of individuality promises to fully recognize the uniqueness of the individual who needs to be seen and treated with utter respect for his or her individuality. It will not be long until digitizing a person unlocks the cause for what is wrong, creating valuable knowledge that can save a life or markedly improve the quality of life. On the other hand, emerging m-health technologies provide fundamentally different ways of looking at tailored communication technology. As a result, tailored communications research is poised at a crossroads. It needs to both build on and break away from existing frameworks into new territory, realizing the necessary commitment to theory-driven research at basic, methodological, clinical, and applied levels. The chapter envisions tailored m-health communication in the context of the science of individuality, emphasizing the variability, stability, and centrality of the individual.

scholarly journals Profiling of primary metabolites in grapes of interspecific grapevine varieties: sugars and organic acids

2011 ◽  
Vol 29 (No. 4) ◽  
pp. 361-372 ◽  
Author(s):  
P. Pavloušek ◽  
M. Kumšta
Keyword(s):  
Cluster Analysis ◽  
Organic Acids ◽  
Vitis Vinifera ◽  
Hplc Method ◽  
The Other ◽  
Vitis Vinifera L ◽  
Primary Metabolites ◽  
Primary And Secondary Metabolites ◽  
The Individual

The quality of grapes is determined above all by the contents of the primary and secondary metabolites. The primary metabolites involve sugars and organic acids, and just these compounds are dealt with in this study. Its objective was to analyse and critically evaluate the primary metabolites in new interspecific varieties and, based on a comparison with European varieties of grapevine (Vitis vinifera L.), to find out the similarities and also possible differences between them. The study evaluates and compares 4 conventional varieties of Vitis vinifera with 11 new interspecific cultivars. The contents and compositions of the individual sugars and acids were estimated by means of the HPLC method. Most of these varieties belong to the group with either medium or low content of malic acid, i.e. with a medium to high β ratio. This corroborates the similarity of interspecific varieties to those of V. vinifera. The cluster analysis identified the existence of two interesting groups of varieties: the first one involved the varieties Riesling, Nativa, Marlen, and Kofranka while the other group consisted of varieties Blaufränkisch, Blauer Portugieser, and Laurot. This observation also indicates similarity between Vitis vinifera L. varieties and interspecific cultivars and demonstrates that the contents of the primary metabolites (i.e. sugars and organic acids) are also comparable.

Security Design

2018 ◽  
Vol 9 (2) ◽  
pp. 33-45
Author(s):  
Paweł Kępka
Keyword(s):  
Human Life ◽  
The Other ◽  
Design Criteria ◽  
Security Design ◽  
Potential Threat ◽  
Sense Of Security ◽  
Protected Values ◽  
The Individual

The article presents issues related to  security design including, among others, the classification of security design, criteria for its division, the essence of design, security interests and objectives, security determinants (environment), concepts for safety-enhancing activities under specified conditions, security potential and the concept of security enhancing activities. The considerations are based on the assumption that security is first and foremost based on the need to protect against the real risks posed by elements that could negatively affect individuals, communities or entire countries. On the other hand, the long history, beyond the defined approach to  providing security, resulting strictly from the willingness to  live in  a  specific environment (space), indicates cases in which the sense of security is related to the authority, capabilities, quality of assets and resources possessed. Both of the approaches presented emphasise that, regardless of their attitude, the issue of protection of human life and health is the most important category of things to be protected. The first approach indicates a reactionary character, closely related to intervention in respect of a given threat (real or imaginary), while the second one draws the perspective of organising the security potential that constitutes the strength of the individual in general, including the case of a real threat. It is a sign of preparing resources (legal, organisational, material, financial, informational) for the potential threat from nature, another person or a country. The concepts defined for preparing for what becomes a threat to the protected values are not only logical, but can also be seen in a hierarchical way. The proof in this case is that, first of all, people repel what threatens them here and now and only then do they think about building their security potential as an answer to what they may face in the future.

scholarly journals Diabetic Rats Present High Mean Platelet Count in the Presence of Oral Infections

2017 ◽  
Vol 28 (5) ◽  
pp. 548-551 ◽  
Author(s):  
Luciana Louzada Ferreira ◽  
João Eduardo Gomes Filho ◽  
Dóris Hissako Sumida ◽  
Suely Regina Mogami Bonfim ◽  
Gustavo Sivieri-Araújo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Platelet Count ◽  
Periodontal Disease ◽  
Rat Model ◽  
Inflammatory Diseases ◽  
Diabetic Rats ◽  
Apical Periodontitis ◽  
Buffer Solution ◽  
Citrate Buffer ◽  
Oral Infections

Abstract Platelet count is associated with inflammatory diseases like diabetes mellitus (DM), which in turn, is related in a bidirectional manner with apical periodontitis and periodontal disease. The aim of this study was to evaluate the effects of apical periodontitis and/or periodontal disease on mean platelet count in a rat model of diabetes mellitus. Eighty Wistar rats were randomly divided into 8 groups (n=10): control (C), apical periodontitis (AP), periodontal disease (PD), apical periodontitis with periodontal disease (AP-PD), diabetes mellitus (DM), diabetes mellitus with apical periodontitis (DM-AP), diabetes mellitus with periodontal disease (DM-PD) and diabetes mellitus with apical periodontitis and periodontal disease (DM-AP-PD). Rats were anesthetized and DM was induced with a single dose of streptozotocin diluted in citrate buffer solution. After 6 days, the DM was confirmed. The animals were sedated and apical periodontitis was induced by dental exposure and periodontal disease was induced by periodontal ligature. After 30 days, animals were anesthetized and the blood was collected by cardiac puncture. Samples were processed and the mean platelet count was obtained. Data were tabulated and subjected to statistical analysis (p<0.05). Diabetic rats had higher mean glycemic levels compared with nondiabetic rats at 6 and 36 days after DM induction (p<0.05). The DM-PD and DM-PD-AP groups showed increased mean platelet count compared to control and AP groups (p<0.05). The periodontal disease alone or associated with apical periodontitis influence mean platelet count in a rat model of diabetes mellitus.

scholarly journals Diabetes mellitus and periodontal diseases: A two way relationship

2021 ◽  
Vol 6 (2) ◽  
pp. 43-56
Author(s):  
Gowhar Nazir ◽  
◽  
Josee Amin ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Systemic Effect ◽  
Diabetic Patients ◽  
Periodontal Infection ◽  
Bidirectional Relationship ◽  
Patients With Diabetes ◽  
Global Health Care

Diabetes mellitus and periodontits are both highly prevalent chronic inflammatory diseases. Both diseases share the same risk factors and are a significant global health care burden adversely affecting the quality of life. Evidence from various studies have demonstrated that diabetes is a major risk factor for periodontal disease and is associated with increased incidence, prevalence and severity of periodontal disease. Hyperglycemia associated with diabetes mellitus results in an increased host immunoinflammatory response which adversely affects the periodontal health. Conversely, periodontits is associated with poor metabolic control in patients with diabetes and increased development of diabetic complications suggesting a bidirectional relationship between the two diseases. Periodontal infection via bacteremia exerts a wide systemic effect by contributing to chronic systemic inflammatory burden worsening diabetic state by increasing insulin resistance. Moreover, studies have demonstrated an improvement in glycemic control following periodontal therapy in prediabetic and diabetic patients with periodontitis.

scholarly journals Odpowiedzialność człowieka za przyrodę w perspektywie kryzysu ekologicznego

2007 ◽  
Vol 5 (1) ◽  
pp. 115-124
Author(s):  
Aleksandra Kuzior
Keyword(s):  
Sustainable Development ◽  
Ecological Crisis ◽  
The Other ◽  
Future Generations ◽  
Natural Sources ◽  
The Sustainable Development ◽  
Radical Reduction ◽  
Set Up ◽  
The Individual

The article takes up the issues connected to the ecological crisis, causes of which refer to uncontrolled scientifically-technical development, predatory administration of the natural sources of Earth and disrespect of the nature, following from the anthropocentric axiology, the analysis of the Stockholm’s Declaration, the Declaration from Rio and the declaration from Johannesburg, as documents forming the idea of the sustainable development, active that care and respect of nature and preventing degratation of natural environment make a basis of the agricultural and social development and the only rational way to get out of the ecological crisis without radical reduction the quality of human’s life. In discussed declarations they point out the individual, collective and institutional responsibility. It’s set up that the basis of the responsibility figured out like that - for the other human, for present and future generations, for the nature, for the global human’s society, for other communities of alive creatures, for the planet - should be ecophilosophy and systematic sozology. Basing on this two sciences we can make a socio-economical and ecological order indicated in the sustainable development conception.

scholarly journals The burden of isolation to the individual: a comparison between isolation for COVID-19 and for other influenza-like illnesses in Japan

2021 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Norio Ohmagari ◽  
Philippe Beutels
Keyword(s):  
Disease Burden ◽  
Severe Disease ◽  
Productivity Loss ◽  
The Other ◽  
Secondary Outcome ◽  
Online Questionnaire ◽  
Productivity Losses ◽  
The Individual ◽  
Isolation Period

At present, there is scarce evidence about how much burden the isolation of COVID-19 patients is. We aimed to assess the differences between COVID-19 and other influenza like illnesses in disease burden brought by isolation. We conducted an online questionnaire survey of 302 people who had COVID-19 or other influenza-like illnesses (ILIs) and compared the burden of isolation due to sickness with one-to-one propensity score matching. The primary outcomes are the duration and productivity losses of isolation, the secondary outcome is quality of life (QOL) valuation on the day of the survey. Acute symptoms of outpatient COVID-19 and other ILIs lasted 17 (interquartile range [IQR] 9-32) and 7 (IQR 4-10) days, respectively. The length of isolation due to COVID-19 was 18 (IQR 10-33) days and that due to other ILIs was 7 (IQR 4-11) days, respectively. The monetary productivity loss of isolation due to COVID-19 was 1424.3 (IQR 825.6-2545.5) USD and that due to other ILIs was 606.1 (IQR 297.0-1090.9) USD, respectively. QOL at the time of the survey was lower in the COVID-19 group than in the other ILIs group (0.89 and 0.96, p = 0.001). COVID-19 infection imposes a substantial disease burden, even in patients with non-severe disease. This burden is larger for COVID-19 than other ILIs, mainly because the required isolation period is longer.

scholarly journals Gambaran Bakteri Kontaminan pada Sikat Gigi

2018 ◽  
Vol 2 (1) ◽  
pp. 34
Author(s):  
Perdina Nursidika ◽  
Patricia Gita Naully ◽  
Linda Ayu Lestari
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Contamination ◽  
Systemic Disease ◽  
Intestinal Bacteria ◽  
Systemic Diseases ◽  
Pathogenic Microorganisms ◽  
Common Risk Factor ◽  
Oral Infections ◽  
Methylen Blue ◽  
Abstract Description

Abstract: DESCRIPTION OF BACTERIAL CONTAMINTANT IN TOOTHBRUSH. Brushing activity is an effort to keep oral hygiene from pathogenic microorganisms that can cause infection. Oral infection has been an increasingly common risk factor for systemic disease. Oral infections, especially periodontitis, can affect travel and pathogenesis of a number of systemic diseases, such as cardiovascular disease, bacterial pneumonia, diabetes mellitus, and low birth weight. Keeping your teeth and mouth clean is not enough just brushing your teeth, but replace the toothbrush for a maximum of three months. This study aims to identify the contaminant bacteria found on toothbrushes that have been used for more than 3 months. The method of identification by planting the isolation result of 20 toothbrushes has been used for more than three months on selective media ie blood agar (AD), McConkey Agar (MCA), Eosin Methylen Blue (EMB), Manitol Salt Agar (MSA) . The results showed that all samples of toothbrush were contaminated with Streptococcus and Staphylococcus, 16 samples were Klebsiella (80%), four samples (20%) were Proteus, and one sample (5%) was contaminated with Escherichia. All of the toothbrush samples showed to have been contaminated by bacteria. Bacterial contamination of the toothbrush can be caused by the storage of a toothbrush that is too close to the toilet and toilet, possibly exposed through aerosols containing intestinal bacteria. This toothbrush contamination plays an important role in both oral and systemic diseases, including septicemia and gastrointestinal, respiratory cardiovascularmy, and kidney problems. Abstrak: GAMBARAN BAKTERI KONTAMINAN PADA SIKAT GIGI. Kegiatan menyikat gigi merupakan upaya untuk menjaga kebersihan gigi dan mulut dari mikroorganisme pathogen yang dapat menyebabkan infeksi. Infeksi mulut telah menjadi faktor risiko yang semakin umum untuk penyakit sistemik. Infeksi mulut, terutama periodontitis, dapat mempengaruhi patogenesis dari sejumlah penyakit sistemik, seperti penyakit kardiovaskular, pneumonia bakteri, diabetes mellitus, dan berat badan lahir rendah. Menjaga kebersihan gigi dan mulut tidak cukup hanya menyikat gigi saja, melainkan mengganti sikat gigi maksimal tiga bulan sekali. Penelitian ini bertujuan untuk mengidentifikasi bakteri kontaminan yang terdapat pada pada sikat gigi yang telah digunakan selama lebih dari 3 bulan. Metode identifikasi dengan melakukan penanaman hasil isolasi 20 sikat gigi yang telah digunakan selama lebih dari tiga bulan pada media selektif yaitu agar darah (AD), McConkey Agar (MCA), Eosin Methylen Blue (EMB), Manitol Salt Agar (MSA) dengan metode gores.  Hasil penelitian menunjukkan semua sampel sikat gigi terkontaminasi Streptococcus dan Staphylococcus, 16 sampel terdapat Klebsiella (80%), pada empat sampel (20%) terdapat Proteus, dan satu sampel (5%) terkontaminasi Escherichia. Semua sampel sikat gigi menunjukkan telah terkontaminasi oleh bakteri. Kontaminasi bakteri pada sikat gigi ini dapat disebabkan oleh penyimpanan sikat gigi yang terlalu dekat dengan jamban, sehingga kemungkinan terpapar melalui aerosol yang mengandung bakteri usus. Kontaminasi sikat gigi ini memegang peranan penting pada penyakit oral maupun sistemik, termasuk septikemia dan gastrointestinal, kardiovaskularm pernapasan, dan masalah ginjal.

scholarly journals A medicalização da morte e os cuidados paliativos [Medicalization of death and palliative care] [La medicalización de la muerte y los cuidados paliativos]

2019 ◽  
Vol 27 ◽  
pp. e41021
Author(s):  
Alessandra Zanei Borsatto ◽  
Ana Dulce Santana dos Santos ◽  
Jane Márcia Progianti ◽  
Octavio Muniz da Costa Vargens
Keyword(s):  
Palliative Care ◽  
The Other ◽  
Death Process ◽  
Paradigm Change ◽  
Historical Process ◽  
Calidad De Vida ◽  
Starting Point ◽  
Life Threatening ◽  
The Individual

Objetivo: refletir sobre o processo histórico da medicalização da morte e como os cuidados paliativos podem modificar esse cenário. Conteúdo: o ponto de partida é a discussão de como ocorreu, ao longo dos séculos, o processo de medicalização da sociedade e da morte para, a seguir, apresentando a proposta dos cuidados paliativos, discutir como essa abordagem pode promover a desmedicalização do processo de morte. Conclusão: a medicalização da morte é um processo que se consolidou ao longo dos séculos, ganhando força através do modelo hospitalocêntrico de atenção à saúde. Por outro lado, a proposta dos cuidados paliativos se apresenta como uma possibilidade de mudança de paradigma na convivência com uma doença ameaçadora da vida e frente ao processo de morte uma vez que seu objetivo é melhorar a qualidade de vida do indivíduo de acordo com as suas prioridades, valorizando a sua autonomia. Dessa maneira, o cuidado paliativo pode ser promotor da desmedicalização da morte.ABSTRACTObjective: to reflect on the historical process of the medicalization of death and how palliative care can modify this scenario. Content: the starting point is the discussion of how the process of medicalization of society and death took place over the centuries, and then, presenting the palliative care proposal, to discuss how this approach can promote the demedicalization of the death process. Conclusion: the medicalization of death is a process that has been consolidated over the centuries, gaining strength through the hospital-centered model of health care. On the other hand, the proposal of palliative care presents itself as a possibility of paradigm change in the coexistence with a life threatening disease and in the death process since its objective is to improve the quality of life of the individual according to their their autonomy. In this way, palliative care can be the promoter of demedicalization of death.RESUMENObjetivo: reflexionar sobre el proceso histórico de la medicalización de la muerte y cómo los cuidados paliativos pueden modificar ese escenario. Contenido: el punto de partida es la discusión de cómo ocurrió, a lo largo de los siglos, el proceso de medicalización de la sociedad y de la muerte para, a continuación, presentar la propuesta de los cuidados paliativos, discutir cómo este enfoque puede promover la desmedicalización del proceso de muerte. Conclusión: la medicalización de la muerte es un proceso que se ha consolidado a lo largo de los siglos, ganando fuerza a través del modelo hospitalocéntrico de atención a la salud. Por otro lado, la propuesta de los cuidados paliativos se presenta como una posibilidad de cambio de paradigma en la convivencia con una enfermedad amenazadora de la vida y frente al proceso de muerte una vez que su objetivo es mejorar la calidad de vida del individuo de acuerdo con las suyas prioridades, valorando su autonomía. De esta manera, el cuidado paliativo puede ser promotor de la desmedicalización de la muerte.

Sign in / Sign up

Export Citation Format

Share Document