scholarly journals Cellular Mechanisms in Regulating Mammary Cell Turnover During Lactation and Dry Period in Dairy Cows

2008 ◽  
Vol 91 (6) ◽  
pp. 2319-2327 ◽  
Author(s):  
J.V. Nørgaard ◽  
P.K. Theil ◽  
M.T. Sørensen ◽  
K. Sejrsen
2011 ◽  
Vol 24 (4) ◽  
pp. 485-492
Author(s):  
Xiaoqing Peng ◽  
Lin Lu ◽  
Yan Li ◽  
Peishi Yan

2006 ◽  
Vol 89 (12) ◽  
pp. 4632-4639 ◽  
Author(s):  
M.T. Sorensen ◽  
J.V. Nørgaard ◽  
P.K. Theil ◽  
M. Vestergaard ◽  
K. Sejrsen

2015 ◽  
Vol 55 (5) ◽  
pp. 630 ◽  
Author(s):  
Tong Qin ◽  
Haoyu Wang ◽  
Dengpan Bu ◽  
Haisheng Hao ◽  
Dong Wang ◽  
...  

The objective of this study was to evaluate the effects of two different forage sources on mammary gland growth, mammary cell turnover and activity in early lactation dairy cows. Twelve early lactation cows were randomly assigned to a CS (33.8% corn straw as sole forage) or MF diet (3.7% Chinese wildrye + 28.4% alfalfa hay + 26.5% corn silage as mixed forage). All cows were fed from Week –3 to Week 8, and mammary biopsies were taken on 16 days postpartum. Mammary cell proliferation and apoptosis were determined by immunohistology, and genes expression in mammary were detected by real-time PCR. Results showed that cell proliferation, gene expression of milk proteins and proteins involved in the synthesis of milk components did not differ between two dietary treatments (P > 0.05). However, cows fed the MF diet had a higher IGF-1 receptor (IGF-1R) expression (P = 0.02), and lower rate of cell apoptosis (P = 0.003) relative to cows fed the CS diet. Collectively, these results suggest that the mammary secretory activity probably was not affected by the dietary treatments, but high quality and mixed forages led to the increased expression of IGF-1R and a larger number of cells in mammary glands, which may be responsible for the higher milk production in early lactation dairy cows.


2011 ◽  
Vol 94 (9) ◽  
pp. 4623-4635 ◽  
Author(s):  
F. Dessauge ◽  
V. Lollivier ◽  
B. Ponchon ◽  
R. Bruckmaier ◽  
L. Finot ◽  
...  

2005 ◽  
Vol 88 (3) ◽  
pp. 975-982 ◽  
Author(s):  
J. Nørgaard ◽  
A. Sørensen ◽  
M.T. Sørensen ◽  
J.B. Andersen ◽  
K. Sejrsen

2021 ◽  
Vol 53 (2) ◽  
Author(s):  
A. Boustan ◽  
V. Vahedi ◽  
M. Abdi Farab ◽  
H. Karami ◽  
R. Seyedsharifi ◽  
...  

1996 ◽  
Vol 63 (2) ◽  
pp. 201-213 ◽  
Author(s):  
J. M. Moorby ◽  
R. J. Dewhurst ◽  
S. Marsden

AbstractEffects of feeding a protein supplement to dairy cows during the dry period on performance during the following lactation were investigated in two experiments. Holstein-Friesian cows were paired towards the end of lactation, and, after drying off, one of each pair received a typical dry cow management regime of ad libitum grass silage (experiment 1), or a mix of grass silage and distillers' grains or pressed beet pulp (experiment 2). The other cows were offered restricted access to the same basal diet, together with ad libitum access to barley straw and 0·5 kg/day high protein maize gluten meal. During the following lactation, animals from both groups were treated without reference to dry period treatment, and were offered equal access to the same lactation diet. Data were analysed by analysis of variance of experiment means and by parallel curve analysis using sample means. In experiment 1, milk yields were similar (27·2 v. 27·9 (s.e.d. 2·12) kg/day for control and supplemented animals respectively) but milk protein yields, and hence concentrations, were significantly higher (P < 0·001) from supplemented animals (28·9 v. 31·8 (s.e.d. 0·58) g/kg). In experiment 2, milk yields were significantly higher (P < 0·001) from supplemented animals (mean 33·3 v. 35·4 (s.e.d. 1·66) kg/day; however, milk protein yields were also significantly increased (P < 0·001) and the change in milk protein concentration was small. No difference in dry-matter intake was recorded in a subset of animals during early lactation in experiment 2. It is hypothesized that the maternal labile body protein pool was maintained or replenished during the dry period by the provision of the protein supplement, and that this had a significant effect on subsequent lactation performance.


2021 ◽  
Vol 37 (5) ◽  
pp. 635-640
Author(s):  
Ahmadreza Mirzaei ◽  
Elizabeth A. Cox ◽  
Scott T. Kieser ◽  
Barbara Petersen ◽  
Todd R. Bilby ◽  
...  

2017 ◽  
Vol 84 (4) ◽  
pp. 414-417 ◽  
Author(s):  
Mario Baratta ◽  
Silvia Miretti ◽  
Paolo Accornero ◽  
Giovanna Galeati ◽  
Andrea Formigoni ◽  
...  

The work reported in this Research Communication describes the modification in epithelial cell populations during the first and the last month of milking in Holstein Friesian cows that have undergone different management during the dry period, and we report the differential expression of CD49f+ and cytokeratin18+ cell subpopulations. Twenty six cows were randomly divided into 2 balanced groups that were housed at stocking density of either 11 m2 (CTR) or 5 m2 from 21 ± 3 d before the expected calving until calving. Cells collected from milk samples taken in early lactation and late lactation were directly analysed for CD45, CD49f, cytokeratin 14, cytokeratin 18 and cell viability. We observed a differential expression with a significant reduction in CD49f+ (P < 0·01) and cytokeratin 18+ (P < 0·05) cells in early lactation. Differences were still evident in late lactation but were not significant. These observations suggest that mammary epithelial cell immunophenotypes could be associated with different animal management in the dry period and we hypothesise they may have a role as biomarkers for mammary gland function in dairy cows.


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