scholarly journals Levofloxacin efficacy in current surgical practice

2021 ◽  
Vol 3 (2) ◽  
pp. 11-16
Author(s):  
O A Nazarchuk ◽  
Yu M Babina ◽  
D V Dmytriiev ◽  
V L Vitkovskiy
Keyword(s):  
Medical Practice ◽  
Soft Tissues ◽  
Infectious Complications ◽  
International Studies ◽  
Clinical Use ◽  
High Efficacy ◽  
Resistance Development ◽  
Surgical Practice ◽  
Prevention And Treatment ◽  
Article Analysis

Results of domestic and international studies of the 3rd generation fluorchinolone Levofloxacin use in the prevention and treatment of inflammative diseases of the skin, soft tissues, intrabdominal and urogenital infectious complications is presented in the article. Analysis of clinical use of Levofloxacin in the treatment of many diseases indicates its high efficacy, absence of complications, low risk of resistance development, that allows to recommend it for the wide use in in medical practice.

scholarly journals Modern opportunities for the prevention and treatment of inflammatory eye diseases of an infectious nature in children

2020 ◽  
Vol 12 (4) ◽  
pp. 57-65
Author(s):  
Vladimir V. Brzheskiy
Keyword(s):  
Surgical Procedures ◽  
Inflammatory Diseases ◽  
Infectious Complications ◽  
Eye Diseases ◽  
Eye Drops ◽  
High Efficacy ◽  
Bacterial Conjunctivitis ◽  
Perioperative Prophylaxis ◽  
Prevention And Treatment ◽  
Chronic Conjunctivitis

The development of inflammatory diseases of the cornea and conjunctiva, as well as the occurrence of infectious complications of intraocular surgery, are largely associated with the presence of saprophytic and pathogenic microflora in the conjunctival cavity. This circumstance is more characteristic of children. At the same time, the possibilities of antibacterial therapy of inflammatory eye diseases of bacterial and chlamydial etiology, as well as perioperative prophylaxis of infectious complications of intraocular surgical procedures in children, have significantly expanded today. The widespread use of fluoroquinolones has significantly improved the treatment of children with acute and chronic bacterial conjunctivitis, keratitis, blepharitis, meibomyitis, chalazion, as well as those with chronic conjunctivitis of chlamydial etiology. At the same time, levofloxacin fluoroquinolone of the 3rd generation, which is used in our country in the form of a 0.5% solution as eye drops Oftaquix (Santen, Finland), has demonstrated high efficacy for this purpose. The widespread introduction of the original 0.5% levofloxacin (Oftaquix), in the treatment regimen for children with inflammatory diseases of the cornea and conjunctiva, as well as for a perioperative prevention of infectious complications of surgical procedures involving them, is a promising way to solve the problem.

On the use of rifampicin in the prevention and treatment of infectious complications in patients with traumatological and orthopedic profile

1998 ◽  
Vol 79 (6) ◽  
pp. 447-449
Author(s):  
Y. M. Ishenin ◽  
D. G. Danilov ◽  
А. N. Yelizov ◽  
T. А. Ardavichene ◽  
Z. V. Koshkareva ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Infectious Complications ◽  
Special Place ◽  
Prevention And Treatment

Among the possible complications of extra-focal transosseous osteosynthesis, a special place is occupied by suppuration of soft tissues at the sites of transosseous elements. Wrong tactics with long-lasting inflammation leads to the formation of abscesses, phlegmon, paratraumatic eczema, the development of dermatitis, and spoke osteomyelitis.

scholarly journals Application of the damage control principles and the use of a local negative pressure system for the prevention of infectious complications in a patient with traumatic separation of the upper limb and massive damage to soft tissues

2020 ◽  
Vol 6 (4) ◽  
pp. 22-25
Author(s):  
I. M. Batyrshin ◽  
M. I. Kizyavka ◽  
D. S. Sklizkov ◽  
Yu. S. Ostroumova ◽  
E. P. Mikhelson ◽  
...  
Keyword(s):  
Upper Limb ◽  
Successful Treatment ◽  
Negative Pressure ◽  
Clinical Case ◽  
Soft Tissues ◽  
Damage Control ◽  
Infectious Complications ◽  
Pressure System

The article presents a clinical case of the successful treatment of a patient with traumatic separation of the upper limb and massive damage to the soft tissues of the upper shoulder and chest. The effectiveness of applying the damage control principles and the method of local negative pressure for the prevention of local and systemic infectious complications is emphasized.

scholarly journals Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
S. V. Karuppiah ◽  
A. J. Johnstone
Keyword(s):  
Total Knee Replacement ◽  
Knee Replacement ◽  
Skin Necrosis ◽  
Low Molecular Weight Heparin ◽  
Rare Case ◽  
Low Molecular Weight ◽  
Clinical Use ◽  
Unfractioned Heparin ◽  
Prevention And Treatment ◽  
Total Knee

Thromboprophylaxis are routinely given to prevent venous thromboembolism (VTE) in patients after total hip and knee replacement surgeries. Low molecular weight heparin (LMWH) (fractioned heparin) is effective in the prevention and treatment of VTE. The predicable effect of LMWH has popularized it for routine clinical use. Although LMWH has lesser complication rate, compared to unfractioned heparin (UFH), sporadic clinical complication has been reported. We report a rare case of skin necrosis secondary to use of LMWH tinzaparin used for routine thromboprophylaxis after total knee replacement.

scholarly journals Forensic autopsy costs in the city of São Paulo

2003 ◽  
Vol 121 (3) ◽  
pp. 139-142 ◽  
Author(s):  
Fernando Augusto Mardiros Herbella ◽  
Pedro Herbella Fernandes ◽  
Carlos Delmonte ◽  
José Carlos Del Grande
Keyword(s):  
Cost Analysis ◽  
Medical Practice ◽  
Central Office ◽  
Diagnostic Procedures ◽  
Direct Costs ◽  
Sao Paulo ◽  
International Studies ◽  
São Paulo ◽  
Modern Medical Practice ◽  
The City

CONTEXT: Modern medical practice involves cost analysis of therapeutic and diagnostic procedures. There are no papers dealing with this theme in relation to forensic autopsies in our country. OBJECTIVE: Analysis of direct costs of forensic autopsies. TYPE OF STUDY: Cost analysis. SETTING: São Paulo Medical Examiner's Central Office. SAMPLE: Year 2001 activity. PROCEDURES: Routine forensic autopsies. MEAN MEASUREMENTS: Analysis of direct costs of personnel and material. RESULTS: Cost of personnel represents 90.38% or US$ 93.46. Material expenses comprised 9.62% or US$ 9.95. Total costs were calculated to be US$ 103.41. CONCLUSIONS: Forensic autopsies have a high cost. Cases to be autopsied should be judiciously selected. Our results are similar to international studies if data are rearranged based on the number of annual necropsies.

scholarly journals Molecular and clinical predictors of inhibitor risk and its prevention and treatment in mild hemophilia A

Blood ◽  
2014 ◽  
Vol 124 (15) ◽  
pp. 2333-2336 ◽  
Author(s):  
Giancarlo Castaman ◽  
Karin Fijnvandraat
Keyword(s):  
Factor Viii ◽  
Hemophilia A ◽  
Biological Response ◽  
Interindividual Variation ◽  
Clinical Use ◽  
Clinical Predictors ◽  
Inhibitor Development ◽  
Prevention And Treatment ◽  
Selection Of

Abstract The risk for inhibitor development in mild hemophilia A (factor VIII levels between 5 and 40 U/dL) is larger than previously anticipated, continues throughout life, and is particularly associated with certain mutations in F8. Desmopressin may reduce inhibitor risk by avoiding exposure to FVIII concentrates, but the heterogenous biological response to desmopressin, showing large interindividual variation, may limit its clinical use. However, predictors of desmopressin response have been recently identified, allowing the selection of the best candidates to this treatment.

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