scholarly journals PREVALENCE OF ANTIBIOTIC RESISTANCE AMONG ESCHERICHIA COLI, MEMBER OF NORMAL FECAL FLORA, ISOLATED IN CHILDREN IN TIRANA, ALBANIA

2020 ◽  
Vol 10 (3) ◽  
pp. 577-582
Author(s):  
Denada Lacej ◽  
◽  
Irida Ikonom Hoxha ◽  
Majlinda Sana ◽  
Esmeralda Meta ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Fecal Flora

scholarly journals High rates of antibiotic resistance among normal fecal flora Escherichia coli isolates in children from Greece

1998 ◽  
Vol 4 (10) ◽  
pp. 563-569 ◽  
Author(s):  
A.C. Vatopoulos ◽  
E. Varvaresou ◽  
E. Petridou ◽  
M. Moustaki ◽  
M. Kyriakopoulos ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Fecal Flora

scholarly journals Prevalence of Antibiotic Resistance in Escherichia coli from the Fecal Flora of Humans in a Rural Area of Songkhla Province

2019 ◽  
Author(s):  
Salisa Prasertsiriphong ◽  
Rattanaporn Chootong ◽  
Silom Jamulitrat ◽  
Manthana Phengmak
Keyword(s):  
Escherichia Coli ◽  
Drug Resistance ◽  
Antibiotic Resistance ◽  
Rural Area ◽  
Multidrug Resistant ◽  
Fecal Flora ◽  
E Coli ◽  
Resistant Strains ◽  
Resistance Rates ◽  
Stool Cultures

Objective: To determine the prevalence of antibiotic resistance in fecal Escherichia coli (E. coli ) isolated from humans in a rural area of Songkhla province.Meterial and Methods: E. coli strains were isolated from the stool cultures of 75 healthy volunteers in a rural area. Resistance rates for 8 antibiotics were determined.Results: The resistance rates for amoxicillin, doxycyclin, cotrimoxazole, gentamicin and cefazolin were 53.3, 51.3, 24.0, 5.3 and 3.3%, respectively. No resistance to norfloxacin, ceftriaxone, and imipenem were detected.Conclusion: The most prevalent resistant strains were found against amoxicillin. The prevalence of drug resistance in all multidrug resistant isolates were resistant to amoxicillin and doxycycline. No strains were resistant to all antibiotics in all antimicrobial categories as all the strains were found to be sensitive to ceftriazone, norfloxacin and imipenem.

scholarly journals Specific phenotypic, genomic, and fitness evolutionary trajectories toward streptomycin resistance induced by pesticide co-stressors in Escherichia coli

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Yue Xing ◽  
Xiaoxi Kang ◽  
Siwei Zhang ◽  
Yujie Men
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Selective Pressure ◽  
Fold Increase ◽  
Streptomycin Resistance ◽  
Evolutionary Stage ◽  
Fitness Costs ◽  
Evolutionary Trajectories ◽  
K 12 ◽  
Late Stages

AbstractTo explore how co-occurring non-antibiotic environmental stressors affect evolutionary trajectories toward antibiotic resistance, we exposed susceptible Escherichia coli K-12 populations to environmentally relevant levels of pesticides and streptomycin for 500 generations. The coexposure substantially changed the phenotypic, genotypic, and fitness evolutionary trajectories, resulting in much stronger streptomycin resistance (>15-fold increase) of the populations. Antibiotic target modification mutations in rpsL and rsmG, which emerged and dominated at late stages of evolution, conferred the strong resistance even with less than 1% abundance, while the off-target mutations in nuoG, nuoL, glnE, and yaiW dominated at early stages only led to mild resistance (2.5–6-fold increase). Moreover, the strongly resistant mutants exhibited lower fitness costs even without the selective pressure and had lower minimal selection concentrations than the mildly resistant ones. Removal of the selective pressure did not reverse the strong resistance of coexposed populations at a later evolutionary stage. The findings suggest higher risks of the selection and propagation of strong antibiotic resistance in environments potentially impacted by antibiotics and pesticides.

scholarly journals Comparison of Antibiotic Resistance Profile of Escherichia coli between Pristine and Human-Impacted Sites in a River

Antibiotics ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 575
Author(s):  
Emi Nishimura ◽  
Masateru Nishiyama ◽  
Kei Nukazawa ◽  
Yoshihiro Suzuki
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Resistant Bacteria ◽  
Downstream Site ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Upstream Site ◽  
Resistance Profile ◽  
Antibiotic Resistance Profile ◽  
Significant Difference

Information on the actual existence of antibiotic-resistant bacteria in rivers where sewage, urban wastewater, and livestock wastewater do not load is essential to prevent the spread of antibiotic-resistant bacteria in water environments. This study compared the antibiotic resistance profile of Escherichia coli upstream and downstream of human habitation. The survey was conducted in the summer, winter, and spring seasons. Resistance to one or more antibiotics at upstream and downstream sites was on average 18% and 20%, respectively, and no significant difference was observed between the survey sites. The resistance rates at the upstream site (total of 98 isolated strains) to each antibiotic were cefazolin 17%, tetracycline 12%, and ampicillin 8%, in descending order. Conversely, for the downstream site (total of 89 isolated strains), the rates were ampicillin 16%, cefazolin 16%, and tetracycline 1% in descending order. The resistance rate of tetracycline in the downstream site was significantly lower than that of the upstream site. Furthermore, phylogenetic analysis revealed that many strains showed different resistance profiles even in the same cluster of the Pulsed-Field Gel Electrophoresis (PFGE) pattern. Moreover, the resistance profiles differed in the same cluster of the upstream and the downstream sites. In flowing from the upstream to the downstream site, it is plausible that E. coli transmitted or lacked the antibiotic resistance gene.

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