scholarly journals Family Support towards Resilience in Adolescents with Type I Diabetes: A Preliminary Study in Indonesia

2019 ◽  
Vol 4 (2) ◽  
pp. 66-71
Author(s):  
Nur Agustini ◽  
◽  
Nani Nurhaeni ◽  
Hening Pujasari ◽  
Elni Abidin ◽  
...  
Keyword(s):  
Family Support ◽  
Type I Diabetes ◽  
Type I ◽  
Preliminary Study

scholarly journals Genetic Polymorphism of β-Casein Gene in Polish Red Cattle—Preliminary Study of A1 and A2 Frequency in Genetic Conservation Herd

Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 377 ◽  
Author(s):  
Anna Cieślińska ◽  
Ewa Fiedorowicz ◽  
Grzegorz Zwierzchowski ◽  
Natalia Kordulewska ◽  
Beata Jarmołowska ◽  
...  
Keyword(s):  
Bioactive Peptides ◽  
Genomic Sequence ◽  
Type I Diabetes ◽  
Significant Risk ◽  
Milk Proteins ◽  
Significant Risk Factor ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Type I ◽  
Preliminary Study

Although there is growing interest in Red cow’s milk in Poland, to date there are few reports investigating the characteristics of milk components in the studied population. Particular emphasis on milk proteins is advised, since β-casein is a source of bioactive peptides named β-casomorphins. β-casomorphin 7, which originates mostly from β-casein variants A1, may be a significant risk factor in human ischemic heart disease, arteriosclerosis, type I diabetes, sudden infant death syndrome, and autism. The aim of the present study was to identify CSN2 polymorphism gene in exon 7 using the genomic sequence from GenBank (M55158), g.8101C>A, (codon 67). Blood samples were collected from 201 Polish Red cattle (24 males and 177 females). The genotype of β-casein was determined using PCR-ACRS. The frequency of β-casein A2 in Polish Red population was 0.47. β-casein A2 frequency in Polish Red bulls and in cows was 0.58 and 0.37, respectively.

Electron microscopy analysis of degenerating pancreatic ß cells in transgenic mice expressing the MHC Class I antigen Dd

1990 ◽  
Vol 48 (3) ◽  
pp. 548-549
Author(s):  
T. A. Stewart ◽  
D. Liggitt ◽  
S. Pitts ◽  
L. Martin ◽  
M. Siegel ◽  
...  
Keyword(s):  
Type I Diabetes ◽  
Disease Process ◽  
Class Ii ◽  
Class I ◽  
Type I ◽  
Aberrant Expression ◽  
Mhc Molecules ◽  
Endogenous Insulin ◽  
Class Ii Mhc ◽  
Ifn Γ

Insulin-dependant (Type I) diabetes mellitus (IDDM) is a metabolic disorder resulting from the lack of endogenous insulin secretion. The disease is thought to result from the autoimmune mediated destruction of the insulin producing ß cells within the islets of Langerhans. The disease process is probably triggered by environmental agents, e.g. virus or chemical toxins on a background of genetic susceptibility associated with particular alleles within the major histocompatiblity complex (MHC). The relation between IDDM and the MHC locus has been reinforced by the demonstration of both class I and class II MHC proteins on the surface of ß cells from newly diagnosed patients as well as mounting evidence that IDDM has an autoimmune pathogenesis. In 1984, a series of observations were used to advance a hypothesis, in which it was suggested that aberrant expression of class II MHC molecules, perhaps induced by gamma-interferon (IFN γ) could present self antigens and initiate an autoimmune disease. We have tested some aspects of this model and demonstrated that expression of IFN γ by pancreatic ß cells can initiate an inflammatory destruction of both the islets and pancreas and does lead to IDDM.

Perceptions of Family Support, Interdependence, and Adherence for Type I Adolescent Diabetics

2009 ◽  
Author(s):  
Hang T. Vu ◽  
Anat Feinstein ◽  
Shannon Casey-Cannon
Keyword(s):  
Family Support ◽  
Type I
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