scholarly journals Supplementation of Enteric-coated Ginger and Garlic Essence Tablet Improved Blood Lipid Profile in Rats Fed High-fat Diet and Hyperlipidemic Subjects

2011 ◽  
Vol 17 (5) ◽  
pp. 409-414
Author(s):  
Bing GU ◽  
Jian YOU ◽  
Yu-Ping LI ◽  
Qiong-Lan YUAN
Keyword(s):  
Lipid Profile ◽  
High Fat Diet ◽  
Blood Lipid ◽  
High Fat ◽  
Blood Lipid Profile ◽  
Enteric Coated

scholarly journals Olive Oil, Palm Oil, and Hybrid Palm Oil Distinctly Modulate Liver Transcriptome and Induce NAFLD in Mice Fed a High-Fat Diet

2018 ◽  
Vol 20 (1) ◽  
pp. 8 ◽  
Author(s):  
Rafael Sales ◽  
Priscylla Medeiros ◽  
Flavia Spreafico ◽  
Patrícia de Velasco ◽  
Fernanda Gonçalves ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Palm Oil ◽  
High Fat Diet ◽  
Protein Localization ◽  
Blood Lipid ◽  
Liver Fat ◽  
High Fat ◽  
Blood Lipid Profile ◽  
High Fat Diets ◽  
Fat Diets

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent worldwide. The most severe form is nonalcoholic steatohepatitis (NASH). Among risk factors for the development of NAFLD is excessive lipid intake. Since palm (P) oil is the most consumed oil in the world, we aimed to investigate the effects of high-fat diets made with P oil, hybrid palm (HP) oil, or olive (O) oil in liver. Twenty-four male mice (C57Bl/6J) were fed a high-fat diet (41% fat) containing P, HP, or O oils for 8 weeks and compared to a control (C) group fed a chow diet. Adiposity was measured with computed tomography. Body, adipose tissue, and liver weights, as well as liver fat (Bligh–Dyer), blood lipid profile, glucose, and liver enzymes were measured. Liver histology (hematoxylin–eosin) and transcriptome (microarray-based) were performed. ANOVA tests with Newman–Keuls were used. Body weight was increased in the P group (p < 0.001) and body fat in the O group (C vs. O p ≤ 0.01, P vs. O p ≤ 0.05, HP vs. O p ≤ 0.05). All high-fat diets disturbed the blood lipid profile and glucose, with marked effects of HP on very low-density lipoprotein cholesterol (VLDL), triglycerides, and alkaline phosphatase (p ≤ 0.001). HP had the highest liver fat (42.76 ± 1.58), followed by P (33.94 ± 1.13). O had a fat amount comparable to C (16.46 ± 0.34, 14.71 ± 0.70, respectively). P and HP oils induced hepatocyte ballooning. Transcriptome alterations of the O group were related to amino acid metabolism and fatty acid (FA) metabolism, the P group to calcium ion homeostasis, and HP oil to protein localization. Both P and HP oils induced NASH in mice via disturbed hepatocyte transcription. This raises concerns about the content of these oils in several industrialized foods.

scholarly journals Effect of Onion Peel Extracts on Blood Lipid Profile and Blood Coagulation in High Fat Fed SD Rats

2011 ◽  
Vol 24 (3) ◽  
pp. 442-450 ◽  
Author(s):  
Hye-Kyung Chung ◽  
Min-Jeong Shin ◽  
Yong-Jun Cha ◽  
Kyung-Hea Lee
Keyword(s):  
Lipid Profile ◽  
Blood Coagulation ◽  
Blood Lipid ◽  
High Fat ◽  
Blood Lipid Profile ◽  
Onion Peel ◽  
Sd Rats

732-P: Effect of Serum 25-Hydroxyvitamin D on Blood Lipid Profile in Type 2 Diabetics

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 732-P
Author(s):  
NAN LI ◽  
YANRU WANG ◽  
BING ZHU ◽  
HANG SUN ◽  
PENG YANG ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Blood Lipid ◽  
Blood Lipid Profile ◽  
Hydroxyvitamin D ◽  
Type 2 Diabetics ◽  
25 Hydroxyvitamin D

scholarly journals Co-Treatment of Purified Annatto Oil (Bixa orellana L.) and Its Granules (Chronic®) Improves the Blood Lipid Profile and Bone Protective Effects of Testosterone in the Orchiectomy-Induced Osteoporosis in Wistar Rats

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4720
Author(s):  
Arlindo César Matias Pereira ◽  
Helison de Oliveira Carvalho ◽  
Danna Emanuelle Santos Gonçalves ◽  
Karyny Roberta Tavares Picanço ◽  
Abrahão Victor Tavares de Lima Teixeira dos dos Santos ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Wistar Rats ◽  
Calcium Concentration ◽  
Calcium Content ◽  
Blood Lipid ◽  
Atomic Absorption Spectrophotometry ◽  
Protective Effects ◽  
Blood Lipid Profile ◽  
Bone Calcium ◽  
Weight Structure

This study aimed to evaluate and compare the effects of co-treatment with purified annatto oil (PAO) or its granules (GRA, Chronic®) with that of testosterone on the orchiectomy-induced osteoporosis in Wistar rats. After surgery, rats were treated from day 7 until day 45 with testosterone only (TES, 7 mg/kg, IM) or TES + PAO or GRA (200 mg/kg, p.o.). The following parameters were evaluated: food/water intake, weight, HDL, LDL, glucose, triglycerides (TG), total cholesterol (TC), alkaline phosphatase levels, blood phosphorus and calcium contents, femur weight, structure (through scanning electron microscopy), and calcium content (through atomic absorption spectrophotometry). Our results show that orchiectomy could significantly change the blood lipid profile and decrease bone integrity parameters. Testosterone reposition alone could improve some endpoints, including LDL, TC, bone weight, and bone calcium concentration. However, other parameters were not significantly improved. Co-treatment with PAO or GRA improved the blood lipid profile and bone integrity more significantly and improved some endpoints not affected by testosterone reposition alone (such as TG levels and trabeculae sizes). The results suggest that co-treatment with annatto products improved the blood lipid profile and the anti-osteoporosis effects of testosterone. Overall, GRA had better results than PAO.

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