scholarly journals Cyclopia: A Rare Congenital Malformation

2018 ◽  
Vol 7 (2) ◽  
pp. 70-73
Author(s):  
Sunil Kumar Yadav ◽  
Arun Giri ◽  
Vijay Kumar Sah
Keyword(s):  
Cholesterol Biosynthesis ◽  
Previous History ◽  
Maternal Diabetes ◽  
Normal Vaginal Delivery ◽  
Second Stage Of Labor ◽  
Large Head ◽  
Causative Factors ◽  
Ultrasound Diagnostics ◽  
History Of ◽  
Incomplete Cleavage

Cyclopia is a rare and lethal congenital anomaly of the forebrain system, resulting from incomplete cleavage of prosencephalon into right and left hemispheres occurring between the 18th and the 28th day of gestation. Approximately 1.05 in 100,000 births are identified as infants with cyclopia, including stillbirths. Many teratogenic factors are identified as the causative factors for this anomaly which include irregular cholesterol biosynthesis, radiation exposure, viruses, alcohol intake and maternal diabetes. Many authors also suggest genetic etiology of this illness. We report a case of 35 year old lady G7P6L5 with previous history of normal vaginal delivery who presented to us in second stage of labor. She delivered a male baby with a large head, a median single eye and absent nose with intact mouth. The baby died soon after the birth. This case is presented because of its rarity. Early ultrasound diagnostics and proper management of this anomaly must be emphasized most strongly to prevent complication associated with this condition.

scholarly journals Holoprosencephaly with cyclopia: a rare case report

2015 ◽  
Vol 1 (1) ◽  
pp. 37 ◽  
Author(s):  
Setu Rathod ◽  
Sunil Kumar Samal ◽  
Jasmina Begum
Keyword(s):  
Cholesterol Biosynthesis ◽  
Previous History ◽  
Maternal Diabetes ◽  
Normal Vaginal Delivery ◽  
Facial Skeleton ◽  
Female Fetus ◽  
Second Stage Of Labour ◽  
Ultrasound Diagnostics ◽  
Rare Case Report ◽  
History Of

<p class="abstract"><span lang="EN-US">Holoprosencephaly (HPE) with cyclopia is a rare congenital anomaly of the forebrain system where due to deformation and hypoplasia of the facial skeleton, one eye orbit is formed in the place where both eyes should be present. Many teratogenic factors are identified as the causative factors for this anomaly which include irregular cholesterol biosynthesis, viruses, alcohol intake and maternal diabetes. Many authors also suggest genetic aetiology of this illness. We report a case of 32 year old lady G<sub>2</sub>P<sub>1</sub>L<sub>1</sub> with previous history of normal vaginal delivery who presented to us in second stage of labour. She delivered a female fetus with multiple defects and later diagnosed as a case of holoprosencephaly with cyclopia. The baby died soon after the birth. This case is presented because of its rarity. Early ultrasound diagnostics and proper management of this anomaly must be emphasized most strongly to prevent complication associated with this condition.</span></p>

scholarly journals PLACENTA PREVIA

2009 ◽  
Vol 16 (01) ◽  
pp. 139-144
Author(s):  
ZOONA SAEED ◽  
M. Saeed ◽  
M. IKRAM ◽  
Roohi Saeed ◽  
SHAZIA TAZIAN
Keyword(s):  
Placenta Previa ◽  
Previous History ◽  
Average Hospital Stay ◽  
Short Term ◽  
Average Hospital ◽  
Intraoperative Complication ◽  
Causative Factors ◽  
History Of ◽  
Rising Incidence ◽  
Post Graduate Institute

Objectives: To analyze the causative factors and short term complications in cases of placenta previa. D e s i g n a ndSettings: A retrospective study carried out in Obstetrics and Gynecology Department of Sheikh Zayed Post Graduate Institute Lahore.P e r i o d : From June 2004 to June 2007.Subject: Fifty patients with placenta previa. M a i n o u t c o m e m e a s u r e s : Age, parity, previouscesarean section, previous history of evacuation/myomectomy, average hospital stay, need for blood transfusions, emergency/electiveLSCS, associated maternal and fetal morbidity and mortality. Results: There were 50 cases of placenta previa over the period of 3 years.Most frequently occurring intra operative complication was postpartum hemorrhage in 19 patients (38%). Highest morbidity was due toanemia which was in 23 patients (46%). Maternal mortality was 2%, while neonatal mortality was 14%. C o n c l u s i o n : Placenta previa is amultifactorial disease. No doubt that the rising incidence of cesarean section is increasing the intraoperative complication associated withthe condition but other risk factors are also important like age, parity, history of evacuation etc.

scholarly journals Prevalence of Hyperthyroidism and its Impact on Quality of Life Among Students of the Islamia University of Bahawalpur Pakistan

2020 ◽  
Vol 8 (2) ◽  
pp. 85-90
Author(s):  
Shifa Shaffique ◽  
Haseeb Anwar ◽  
Hafiz Muhammad Asif ◽  
Imran ul Haq ◽  
Muhammad Akram
Keyword(s):  
Quality Of Life ◽  
Family History ◽  
Previous History ◽  
Previous Treatment ◽  
Population Based ◽  
Causative Factors ◽  
Associated Symptoms ◽  
History Of ◽  
Middle Class Families

Aim: Population based studies on prevalence of hyperthyroidism and its impact on quality of life, with variability of weight, height and distribution, their associated symptoms are limited. Knowledge and awareness about the prevalence of hyperthyroidism and their associated symptoms and its treatment option is necessary for the patient education and evaluation of underlying causative factors of this disease. Methodology: Apopulation-based study was conducted from October 2018 to May 2019 to determine the prevalence of hyperthyroidism and its impact on quality of life among the students of The Islamia University Bahawalpur. Questioner were developed and distributed among the consenting participants. Thirty-six males and one hundred and six females were included in this study. Results: Our study concluded that prevalence of hyperthyroidism is n=10(6.6%) and its prevalence ishigher in middle class families. Hyperthyroidism has a positive link with family history and previous history as shown in the results i.e. n=8 (5.3%) with family history and n=5 (3.3%) linked with previoushistory. It is the leading cause of morbidity and its prevalence is raised day by day. We studied that hyperthyroidism produces following effects on quality of life; n=10 (6.6%) participants were presented with loss of concentration in work / studies=10 (6.6%) with body ache, n=8 (5.3%) with social isolation, n=10 (6.6%) with mental health changes, n=6 (4%) with a history of previous treatment, n=8 (5.3%) with need of repeated checkups. Conclusion: It is concluded from present study that the hypehyperthyroidism significantly affects the quality of life and it is positively linked with the family history and history.

scholarly journals Study on prevalence of prelabour rupture of membranes and its maternal and fetal outcomes

2021 ◽  
Vol 10 (11) ◽  
pp. 4163
Author(s):  
Mamatha Poondru ◽  
R. Kala ◽  
A. Kumar
Keyword(s):  
Risk Factors ◽  
Tamil Nadu ◽  
Post Partum ◽  
Mode Of Delivery ◽  
Previous History ◽  
Active Management ◽  
Normal Vaginal Delivery ◽  
Maternal Complications ◽  
Cross Sectional ◽  
History Of

Background: The aim is to study the prevalence of prelabour rupture of the membranes (PROM), to identify risk factors, mode of delivery, and its maternal and fetal effects.Methods: This was a cross-sectional study conducted in the department of obstetrics and gynaecology at Government Head Quarters Hospital, Cuddalore, Tamil Nadu, with a duration of 6months (January 2020 – June 2020). The study was conducted on 800 pregnant women between 28-42 weeks of gestational age consecutively and those who met the inclusion and exclusion criteria were taken into study.Results: The prevalence of PROM was 27.9% (tPROM 24.6% and PPROM 3.2%). Most of the cases were primigravida (74%). Risk factors associated with PROM were low socioeconomic state (63.2%), urinary tract infection (UTI) (7.2%), vaginal infections (5.8%), and previous history of PROM (3.1%). Most of the patients were delivered by lower segment caesarean section (LSCS) (55.2%), normal vaginal delivery (39.9%) and forceps delivery (4.9%). The most common indication for LSCS was fetal distress (43.9%). Misoprostol induction was associated with more failed induction (2 times) than syntocinon. Maternal complications were post-partum haemorrhage (PPH) (8%), fever (6.7%), wound infection (6.2%), manual removal of placenta (4.4%), and puerperal sepsis (0.9%). Neonatal complications were neonatal intensive care unit (NICU) admissions (14%), respiratory distress syndrome (RDS) (11%), neonatal sepsis (2.6%). Maternal (54.5%) and neonatal (90%) morbidity were more in prolonged PROM >24 hours.Conclusions: Antenatal screening for genitourinary infections especially in cases of the previous history of abortions and PROM should be done. Oxytocin is the preferred method of induction over misoprostol in this study. Active management in term PROM cases can reduce the cesarean section rate.

Incidence of cesarean delivery after induction of labour with dinoprostone gel at term in nulliparous women with unfavourable bishops score

2017 ◽  
Vol 6 (4) ◽  
pp. 1253
Author(s):  
Kalpana Mehta ◽  
Dhanesh Kumar ◽  
Dharmendra Singh Fathepuriya ◽  
Leena Verma
Keyword(s):  
Cesarean Section ◽  
Vaginal Delivery ◽  
Previous History ◽  
Fetal Distress ◽  
Induction Of Labour ◽  
Normal Vaginal Delivery ◽  
Bishop Score ◽  
Nulliparous Women ◽  
History Of ◽  
The Mean

Background: The aim of induction of labour is to achieve vaginal delivery in advance of the normal timing of parturition and to avoid operative delivery. The objective was to study the incidence of instrumental delivery and cesarean section in nulliparous women with unfavourable bishops score at term.Methods: This study was conducted on 200 patients in nulliparous women with unfavourable bishop score, cephalic presentation and no previous history of abortion.Results: The most frequent cause of induction of labour was postdatism (47.5%) followed by PIH (25.5%) and PROM (13%). 143 (71.5%) women had normal vaginal delivery whereas in 54 women (27%) cesarean section was done. 2 women (1%) had forceps application for delivery and remaining 1 women (0.5%) had ventouse delivery. Out of 200 patients 9 had maternal complication of induction of labour.Conclusions: In present study 71.5% women had normal vaginal delivery, 27% had cesarean section. Mean bishop score at induction was 3.31 which improved to 4.0 after 12 hours of gel instillation. The mean induction to delivery interval was 13.38 hrs in present study, 54.5% patients were delivered within 12 hours of gel instillation in this study. Most common indication of cesarean section was failed progress followed by fetal distress.

scholarly journals Causative factors of deep vein thrombosis of lower limb in Indian population

2017 ◽  
Vol 5 (1) ◽  
pp. 320
Author(s):  
Reina Khadilkar ◽  
Shubhi P. Bhatnagar ◽  
Preet Dave
Keyword(s):  
Deep Vein Thrombosis ◽  
Previous History ◽  
Vein Thrombosis ◽  
Post Surgery ◽  
Causative Factors ◽  
Common Causes ◽  
History Of ◽  
And Gender ◽  
A Prospective Study ◽  
Deep Vein

Background: Deep vein thrombosis refers to the formation of an abnormal coagulum within the deep venous system. An accurate diagnosis of DVT is extremely important to prevent potentially fatal acute complications of pulmonary embolism (PE) and long-term complications of post phlebitis syndrome and pulmonary hypertension. There are many causative factors for DVT.Methods: This was a prospective study where 50 cases of DVT were admitted in this centre. Patients were evaluated in terms of causative factors of DVT. These were previous history of DVT, immobility, surgery, smoking, obesity and drugs. Age and gender comparisons were also done. The most common causes were recorded.Results: The most common cause was found to be immobility and post-surgery immobilization which constituted 90 % of the patients in the study. Advanced age and male gender showed a higher incidence of DVT.Conclusions: Early identification of the causes and the risk factors in the development of DVT can reduce the burden of the disease and contribute to its prevention and management.

scholarly journals Overt Hyperthyroidism in Third Trimester of Pregnancy: A Case Report

2020 ◽  
Vol 58 (228) ◽  
Author(s):  
Madan Khadka ◽  
Achala Thakur ◽  
Dipti Das ◽  
Akshat Mishra
Keyword(s):  
Beta Blockers ◽  
Previous History ◽  
Normal Vaginal Delivery ◽  
Shortness Of Breath ◽  
Third Trimester ◽  
Healthy Baby ◽  
History Of ◽  
Overt Hyperthyroidism ◽  
Propyl Thiouracil ◽  
Subsequent Onset

Hyperthyroidism is a state of excessive thyroid function. The most common cause of hyperthyroidism is Graves’ disease. Overt hyperthyroidism if not treated can have serious outcome on the mother and the fetus. We present a pregnant women at 31 weeks of gestation presented with shortness of breath and palpitation with previous history of caesarean section and was treated with propyl thiouracil, beta blockers, antihypertensive drug, and during her course of treatment had Preterm Prelabor Rupture of Membrane with subsequent onset of labor and had normal vaginal delivery of 1.7 kg healthy baby. This report emphasize on the timely management of overt symptoms before the onset of labor.

405: Previous History of Bladder Cancer is an Independent Prognostic Factor for Upper Tract Transitional Cell Carcinoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 135-135
Author(s):  
Eiji Kikuchi ◽  
Akira Miyajima ◽  
Ken Nakagawa ◽  
Mototsugu Oya ◽  
Takashi Ohigashi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Factor ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Previous History ◽  
Independent Prognostic Factor ◽  
Upper Tract ◽  
History Of
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