scholarly journals Leucine-rich repeat neuronal 3, LRRN3, is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Leucine Rich Repeat ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the leucine-rich repeat neuronal 3, LRRN3, was among those whose expression was most different in human NSCLC tumors as compared to the lung. LRRN3 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of LRRN3 in patient tumors was significantly associated with worse overall survival. LRRN3 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals Glycoprotein M6A is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that gene encoding glycoprotein M6A, GPM6A, was among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. GPM6A expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of GPM6A in patient tumors was significantly associated with worse overall survival. GPM6A may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals RhoJ is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding RhoJ, the ras homolog family member J (RhoJ) among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. RhoJ expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of RhoJ in patient tumors was significantly associated with worse overall survival. RhoJ may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals The myocardial zonula adherens protein, MYZAP, is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the myocardial zonula adherens protein, MYZAP, was among those whose expression was most different in human NSCLC tumors as compared to the lung. MYZAP expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of MYZAP in patient tumors was significantly associated with worse overall survival. MYZAP may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals Cadherin 5 is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding cadherin 5 (Cdh5) was among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. Cdh5 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of Cdh5 in patient tumors was significantly associated with worse overall survival. Cdh5 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals Pyrroline-5-carboxylate reductase 1, PYCR1, is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Carboxylate Reductase ◽  
Human Nsclc

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding pyrroline-5-carboxylate reductase 1, PYCR1, was among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. PYCR1 expression levels were significantly increased in NSCLC tumors as compared to the lung, and higher expression of PYCR1 in patient tumors was significantly correlated with worse overall survival and decreased time to first progression. PYCR1 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals LRRC36 is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding LRRC36 was among those whose expression was most different in human NSCLC tumors as compared to the lung. LRRC36 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of LRRC36 in patient tumors was significantly associated with worse overall survival. LRRC36 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals The NCK associated protein 5, NCKAP5, is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the NCK associated protein 5, NCKAP5, was among those whose expression was most different in human NSCLC tumors as compared to the lung. NCKAP5 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of NCKAP5 in patient tumors was significantly associated with worse overall survival. NCKAP5 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals Fam107A is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Sequence Similarity ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Human Nsclc

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding family with sequence similarity 107A, Fam107A was among those whose expression was most different in human NSCLC tumors as compared to the lung. Fam107A expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of Fam107A in patient tumors was significantly associated with worse overall survival. Fam107A may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals TCF21 is differentially expressed in non-small cell lung cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Microarray Data ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Cancer Death ◽  
Small Cell Lung ◽  
Gene Encoding

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4, 5) to identify differentially expressed genes in NSCLC. We found that the gene encoding the transcription factor TCF21 was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. TCF21 may be important for initiation or progression of non-small cell lung cancer in humans.

scholarly journals Aspartoacyclase is differentially expressed in non-small cell lung cancer and associates with patient survival.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Patient Survival ◽  
The United States ◽  
Small Cell ◽  
Differentially Expressed ◽  
Small Cell Lung ◽  
Gene Encoding ◽  
Lower Expression

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4, 5) to identify differentially expressed genes in NSCLC. We found that the gene encoding aspartoacyclase (ASPA) was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. ASPA expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of ASPA in patient tumors was significantly associated with worse overall survival. ASPA may be important for initiation or progression of non-small cell lung cancer in humans.

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