Purification of glutathione S-transferase isoenzymes from tumour and nontumour human stomach and inhibitory effects of some heavy metals on enzymes activities

2012 ◽  
Vol 28 (5) ◽  
pp. 911-915 ◽  
Author(s):  
Ramazan Demirdag ◽  
Emrah Yerlikaya ◽  
Omer Irfan Kufrevioglu ◽  
Cemal Gundogdu
Keyword(s):  
Heavy Metals ◽  
Human Stomach ◽  
Inhibitory Effects ◽  
Glutathione S Transferase ◽  
Enzymes Activities

scholarly journals Effects of Total Ginsenosides on the Feeding Behavior and Two Enzymes Activities ofMythimna separata(Walker) Larvae

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Ai-Hua Zhang ◽  
Shi-Qiang Tan ◽  
Yan Zhao ◽  
Feng-Jie Lei ◽  
Lian-Xue Zhang
Keyword(s):  
Feeding Behavior ◽  
Panax Ginseng ◽  
Panax Quinquefolius ◽  
Ecological Role ◽  
Inhibitory Effects ◽  
Glutathione S Transferase ◽  
Mythimna Separata ◽  
Enzymes Activities ◽  
Effective Components ◽  
Antifeeding Activity

Ginsenosides, the main effective components ofPanax ginsengC.A. Meyer andPanax quinquefoliusL., are important allelochemicals ofginseng. Although many studies have targeted the pharmacological, chemical, and clinical properties of ginsenosides, little is known about their ecological role inginsengpopulation adaptation and evolution. Pests rarely feed onginseng, and it is not known why. This study investigated the effects of total ginsenosides on feeding behavior and activities of acetylcholinesterase (AChE) and glutathione s-transferase (GST) inMythimna separata(Walker) larvae. The results showed that the total ginsenosides had significant antifeeding activity againstM. separatalarvae, determined by nonselective and selective antifeeding bioassays. In addition, the total ginsenosides had inhibitory effects on the activities of GST and AChE. The antifeeding ratio was the highest at 8 h, then decreased, and was the lowest at 16 h. Both GST and AChE activities decreased from 0 h to 48 h in all total ginsenosides treatments but increased at 72 h. Total ginsenosides had antifeeding activity againstM. separatalarvae and inhibitory effects on the activities of GST and AChE.

scholarly journals Inhibitory Effects of Heavy Metals on Transcription Factor Sp1.

2000 ◽  
Vol 38 (2) ◽  
pp. 224-227 ◽  
Author(s):  
Pengfei GONG ◽  
Yasumitsu OGRA ◽  
Shinji KOIZUMI
Keyword(s):  
Heavy Metals ◽  
Transcription Factor ◽  
Inhibitory Effects ◽  
Transcription Factor Sp1

scholarly journals Oxidative stress and antioxidant indices of the marine red alga Porphyra vietnamensis

2013 ◽  
Vol 72 (2) ◽  
pp. 197-209 ◽  
Author(s):  
Navnath M. Pise ◽  
Dattatry K. Gaikwad ◽  
Tanaji G. Jagtap
Keyword(s):  
Oxidative Stress ◽  
Heavy Metals ◽  
Red Alga ◽  
Glutathione S Transferase ◽  
Antioxidant Defence ◽  
Antioxidant Defences ◽  
Pollution Levels ◽  
Stress Markers ◽  
Marine Habitats ◽  
Assessment And Monitoring

Abstract -Oxidative stress and antioxidant defence systems were assessed in a marine red alga Porphyra vietnamensis Tanaka et Pham-Hoang Ho, from India. Lipid peroxidation (LPX) and hydrogen peroxide (H2O2) were measured as oxidative stress markers. Antioxidant defences were measured as catalase (CAT), glutathione S-transferase (GST) and ascorbic acid (AsA), in order to understand their dissimilarity with respect to environmental conditions (pollution levels) from selective locations along the central west coast of India. Levels of LPX, H2O2, CAT and GST were significantly higher in samples collected from Dona Paula than in samples from Malvan and Kunkeshwar, while a lower concentration of AsA was found in samples from Dona Paula. Heavy metals such as Cd, Pb and Hg in higher concentrations in these areas than in other sites were also observed. Variation of oxidative stress indices in response to the accumulation of heavy metals within P. vietnamensis could be used as molecular biomarkers for the assessment and monitoring of environmental quality in ecologically sensitive marine habitats.

Ocean acidification: synergistic inhibitory effects of protons and heavy metals on 45Ca uptake by lobster branchiostegite membrane vesicles

2019 ◽  
Vol 189 (5) ◽  
pp. 513-521
Author(s):  
Dalen An ◽  
Aida Husovic ◽  
Laeequa Ali ◽  
Elizabeth Weddle ◽  
Lilian Nagle ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Ocean Acidification ◽  
Membrane Vesicles ◽  
Inhibitory Effects ◽  
45Ca Uptake

Inhibitory Effects of Isoflavones on Tumor Growth and Cachexia in Newly Established Cachectic Mouse Models Carrying Human Stomach Cancers

2013 ◽  
Vol 65 (4) ◽  
pp. 578-589 ◽  
Author(s):  
Kazuyoshi Yanagihara ◽  
Misato Takigahira ◽  
Keichiro Mihara ◽  
Takanori Kubo ◽  
Chie Morimoto ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Mouse Models ◽  
Human Stomach ◽  
Inhibitory Effects
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