scholarly journals Effects of Total Ginsenosides on the Feeding Behavior and Two Enzymes Activities ofMythimna separata(Walker) Larvae

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Ai-Hua Zhang ◽  
Shi-Qiang Tan ◽  
Yan Zhao ◽  
Feng-Jie Lei ◽  
Lian-Xue Zhang
Keyword(s):  
Feeding Behavior ◽  
Panax Ginseng ◽  
Panax Quinquefolius ◽  
Ecological Role ◽  
Inhibitory Effects ◽  
Glutathione S Transferase ◽  
Mythimna Separata ◽  
Enzymes Activities ◽  
Effective Components ◽  
Antifeeding Activity

Ginsenosides, the main effective components ofPanax ginsengC.A. Meyer andPanax quinquefoliusL., are important allelochemicals ofginseng. Although many studies have targeted the pharmacological, chemical, and clinical properties of ginsenosides, little is known about their ecological role inginsengpopulation adaptation and evolution. Pests rarely feed onginseng, and it is not known why. This study investigated the effects of total ginsenosides on feeding behavior and activities of acetylcholinesterase (AChE) and glutathione s-transferase (GST) inMythimna separata(Walker) larvae. The results showed that the total ginsenosides had significant antifeeding activity againstM. separatalarvae, determined by nonselective and selective antifeeding bioassays. In addition, the total ginsenosides had inhibitory effects on the activities of GST and AChE. The antifeeding ratio was the highest at 8 h, then decreased, and was the lowest at 16 h. Both GST and AChE activities decreased from 0 h to 48 h in all total ginsenosides treatments but increased at 72 h. Total ginsenosides had antifeeding activity againstM. separatalarvae and inhibitory effects on the activities of GST and AChE.

Ginseng – die Möglichkeit seiner Anwendung zur Behandlung der Tumor-assoziierten Müdigkeit

2021 ◽  
Vol 53 (02) ◽  
pp. 69-73
Author(s):  
Katrin Pfuhlmann ◽  
Petra Klose ◽  
Tanja Neufeld ◽  
Jost Langhorst
Keyword(s):  
Panax Ginseng ◽  
Panax Quinquefolius

ZUSAMMENFASSUNGVon dem zu den Efeugewächsen gehörigen Ginseng sind vor allem zwei Arten bekannt: Der Asiatische oder Koreanische Ginseng Panax ginseng und der Amerikanische Ginseng Panax quinquefolius. Anwendung finden Verarbeitungen der Ginsengwurzel (Ginseng Radix), welche etliche gesundheitsförderliche Inhaltsstoffe enthält. Die wichtigsten pharmakologisch aktiven Substanzen stellen die Ginsenoside dar. Ginseng gilt als traditionelles Mittel gegen Erschöpfungszustände aller Art. Für diesen Zweck ist der Asiatische Ginseng in Europa als Arzneimittel zugelassen. Ergebnisse hochwertiger randomisierter kontrollierter Studien zeigen erste positive Effekte der Anwendung von Ginseng bei Tumor-assoziierter Müdigkeit und liefern Hinweise für eine toxikologische Unbedenklichkeit des Ginsengs. Auf Grundlage dieser Publikationen wird in der S3-Leitlinie „Komplementärmedizin in der Behandlung von onkologischen PatientInnen“, welche gerade in der Konsultationsfassung vorliegt, über eine evidenzbasierte Empfehlung für die Anwendung von Ginseng bei Tumor-assoziierter Müdigkeit diskutiert. Eine belastbare Aussage hierüber wird in der final veröffentlichten Leitlinie vorliegen.

Inhibitory effects of Panax ginseng glycoproteins in models of doxorubicin-induced cardiac toxicity in vivo and in vitro

2021 ◽  
Author(s):  
Yajun Chen ◽  
Lei Wang ◽  
Tianjia Liu ◽  
Zhidong Qiu ◽  
Ye Qiu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Cell Viability ◽  
Panax Ginseng ◽  
Cardiac Toxicity ◽  
H9c2 Cell ◽  
Inhibitory Effects ◽  
Myocardial Oxidative Stress

We investigated the protective effect of PGP against DOX-induced cardiotoxicity in vitro and in vivo. PGP increases H9C2 cell viability and inhibits apoptosis, alleviating DOX-induced myocardial oxidative stress-related cardiotoxicity.

Development of an EST-SSR marker in Panax ginseng

2008 ◽  
Vol 5 (2) ◽  
pp. 175-181 ◽  
Author(s):  
Yang Cheng-Jun ◽  
Wang Jun ◽  
Mu Li-Qiang ◽  
Li Shao-Chen ◽  
Liu Guan-Jun ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Expressed Sequence Tags ◽  
Genomic Dna ◽  
Ssr Marker ◽  
Panax Quinquefolius ◽  
Chain Reaction ◽  
Acanthopanax Senticosus ◽  
Pcr Products ◽  
Polymerase Chain ◽  
Expressed Sequence

AbstractA total of 791 microsatellites (SSRs) were isolated from 7055 Panax ginseng expressed sequence tags (ESTs). According to primer design criteria, 68 primer pairs for EST-SSR were designed. Under an appropriate polymerase chain reaction (PCR) system, all EST-SSR primer pairs were screened against genomic DNA of Ji'anchangbo and Fusong'ermaya from Panax ginseng, and 43 EST-SSR primer pairs out of the above 68 resulted in PCR products. Then, all 43 pairs were detected in nine P. ginseng, two Panax quinquefolius and two Acanthopanax senticosus cultivars for polymorphisms, and 26 pairs (60.47%) were found to be polymorphic, accounting for 38.23% of the total number of designed primer pairs. These results demonstrate the possibility of developing EST-SSR markers using P. ginseng ESTs.

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