The relative antidepressant efficacy of bilateral compared with non-dominant unilateral electroconvulsive therapy A review

1991 ◽  
Vol 45 (3) ◽  
pp. 207-213
Author(s):  
Dorte Sestoft
Keyword(s):  
Electroconvulsive Therapy ◽  
Antidepressant Efficacy

scholarly journals Biomarkers for Antidepressant Efficacy of Electroconvulsive Therapy: An Exploratory Cerebrospinal Fluid Study

2018 ◽  
Vol 77 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Laura Kranaster ◽  
Carolin Hoyer ◽  
Suna S. Aksay ◽  
J. Malte Bumb ◽  
Norbert Müller ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Electroconvulsive Therapy ◽  
Antidepressant Efficacy

scholarly journals The Longitudinal Effects of Electroconvulsive Therapy on Ictal Interhemispheric Coherence and Its Associations With Treatment Outcome: A Naturalistic Cohort Study

2018 ◽  
Vol 50 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Freek ten Doesschate ◽  
Guido A. van Wingen ◽  
Boudewijn J. H. B. de Pont ◽  
Martijn Arns ◽  
Jeroen A. van Waarde
Keyword(s):  
Cohort Study ◽  
Electroconvulsive Therapy ◽  
Treatment Efficacy ◽  
Rating Scale ◽  
Eeg Coherence ◽  
Mixed Effect ◽  
Frequency Bands ◽  
Interhemispheric Coherence ◽  
Longitudinal Effects ◽  
Antidepressant Efficacy

Objectives. Electroconvulsive therapy (ECT) is an effective treatment for severe depression. Electroencephalogram (EEG) measures between ECT sessions seem to be related to the antidepressant efficacy of ECT. In this naturalistic cohort study, we examine longitudinal effects of ECT on interhemispheric EEG coherence measures during seizure activity and its relation to the antidepressant efficacy. Methods. This study included 65 patients diagnosed with severe depressive disorder. Depressive symptoms were rated according to the Montgomery-Åsberg Depression Rating Scale before and after the course of ECT. Frequency-specific ictal interhemispheric (fp1-fp2) EEG coherence measures were established during the first and each consecutive sixth treatment session. Linear mixed-effect models were used to determine longitudinal changes in ictal coherence measures during the course of ECT and its relation to treatment efficacy. Results. Ictal interhemispheric coherence in the theta and alpha frequency bands increased over the course of treatment, whereas no significant change was found for the delta and beta frequency bands. A main effect of treatment efficacy on the interhemispheric coherence in the delta and theta band was revealed. However, the longitudinal effects of ECT were not associated with treatment efficacy. Conclusion. The current study suggests that interhemispheric coherence during ECT-induced seizures increases over the course of treatment. Furthermore, these longitudinal effects seem to be unrelated to the antidepressant efficacy of ECT. These findings contribute to the understanding of the mechanism of action of ECT.

Effects of Low-Dose Ketamine on the Antidepressant Efficacy and Suicidal Ideations in Patients Undergoing Electroconvulsive Therapy

2020 ◽  
Vol 36 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Qibin Chen ◽  
Jun Dong ◽  
Jie Luo ◽  
Li Ren ◽  
Su Min ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Low Dose ◽  
Antidepressant Efficacy

Technical Aspects of Electroconvulsive Therapy: An Update

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
P. Sienaert
Keyword(s):  
Side Effects ◽  
Electroconvulsive Therapy ◽  
Pulse Width ◽  
Additional Treatment ◽  
Electrode Placement ◽  
Treatment Conditions ◽  
Antidepressant Efficacy ◽  
Remission Criteria ◽  
Standard Pulse ◽  
Cognitive Side Effects

In an ongoing attempt to improve efficacy of electroconvulsive therapy (ECT) while minimizing side-effects, both different electrode placements and stimulus parameters have been studied. It has been shown that the traditional bitemporal electrode placement and modern techniques such as bifrontal and unilateral ECT are efficacious, depending on the stimulus used. Modern ECT-devices deliver a square wave brief pulse stimulus. An unresolved issue in the use of brief pulse stimulation concerns the optimal pulse width. It has been suggested that the use of a stimulus with an ultra brief (UB) pulse width, i.e. 0.3 ms, is substantially more efficient in seizure induction, thus needing less energy, and producing less cognitive side-effects than standard pulse width (i.e. 0.5-2 ms) stimulation. There has been a concern, however, of lower antidepressant efficacy of UB ECT, with patients needing additional treatment sessions. Moreover, it has been suggested that the diminished antidepressive efficacy is encountered solely with the combination of an ultra-brief pulse width and bilateral electrode placement, as compared to unilateral UB ECT or standard pulse ECT. In a randomized trial, the antidepressive efficacy and cognitive side-effects of bifrontal and right unilateral UB ECT were compared. It was shown that, using an ultra-brief pulse width, BF ECT is as efficacious as UL ECT, although patients receiving UL ECT achieved response/remission-criteria after a smaller number of treatments. In both treatment conditions there was an improvement of cognitive function, both during and after the treatment course.

Anaesthesia for electroconvulsive therapy – new tricks for old drugs: a systematic review

2017 ◽  
Vol 30 (2) ◽  
pp. 61-69 ◽  
Author(s):  
Tobias Kvist Stripp ◽  
Martin Balslev Jorgensen ◽  
Niels Vidiendal Olsen
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Electroconvulsive Therapy ◽  
Bispectral Index ◽  
Prospective Studies ◽  
Human Subjects ◽  
Seizure Quality ◽  
Antidepressant Efficacy ◽  
Old Drugs ◽  
Cognitive Side Effects

ObjectiveThe objective of this review is to investigate existing literature in order to delineate whether the use of anaesthesia and timing of seizure induction in a new and optimised way may improve the efficacy of electroconvulsive therapy (ECT).MethodsPubMed/MEDLINE was searched for existing literature, last search on 24 June 2015. Relevant clinical studies on human subjects involving choice of anaesthetic, ventilation and bispectral index (BIS) monitoring in the ECT setting were considered. The references of relevant studies were likewise considered.ResultsPropofol yields the shortest seizures, etomidate and ketamine the longest. Etomidate and ketamine+propofol 1 : 1 seems to yield the seizures with best quality. Seizure quality is improved when induction of ECT is delayed until the effect of the anaesthetic has waned – possibly monitored with BIS values. Manual hyperventilation with 100% O2 may increase the pO2/pCO2-ratio, which may be correlated with better seizure quality.ConclusionEtomidate or a 1 : 1 ketamine and propofol combination may be the best method to achieve general anaesthesia in the ECT setting. There is a need for large randomised prospective studies comparing the effect of methohexital, thiopental, propofol, ketamine, propofol+ketamine 1 : 1 and etomidate in the ECT treatment of major depressed patients. These studies should investigate safety and side effects, and most importantly have antidepressant efficacy and cognitive side effects as outcome measures instead of seizure quality.

Antidepressant efficacy of Sudarshan Kriya Yoga (SKY) in melancholia: a randomized comparison with electroconvulsive therapy (ECT) and imipramine

2000 ◽  
Vol 57 (1-3) ◽  
pp. 255-259 ◽  
Author(s):  
N. Janakiramaiah ◽  
B.N. Gangadhar ◽  
P.J. Naga Venkatesha Murthy ◽  
M.G. Harish ◽  
D.K. Subbakrishna ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Antidepressant Efficacy

Ictal and interictal EEG markers or seizure inhibition predict and index antidepressant efficacy of electroconvulsive therapy

1997 ◽  
Vol 102 (1) ◽  
pp. P25
Author(s):  
James J. Stockard ◽  
Lois E. Kraham ◽  
Kevin O'Connor ◽  
Thomas S. Pileggi ◽  
Teresa A. Rummans
Keyword(s):  
Electroconvulsive Therapy ◽  
Antidepressant Efficacy ◽  
Interictal Eeg

Relationship of seizure duration to antidepressant efficacy in electroconvulsive therapy

1997 ◽  
Vol 27 (6) ◽  
pp. 1373-1380 ◽  
Author(s):  
H. KALES ◽  
J. RAZ ◽  
R. TANDON ◽  
D. MAIXNER ◽  
J. DeQUARDO ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Seizure Duration ◽  
Antidepressant Efficacy ◽  
Relationship Of

Dosage, Seizure Threshold, and the Antidepressant Efficacy of Electroconvulsive Therapy

1986 ◽  
Vol 462 (1 Electroconvul) ◽  
pp. 398-410 ◽  
Author(s):  
HAROLD A. Sackeim ◽  
PAOLO DECINA ◽  
ISAK PROHOVNIK ◽  
STEPHANIE PORTNOY ◽  
MAUREEN KANZLER ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Seizure Threshold ◽  
Antidepressant Efficacy
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