NK Activity in Patients with Pathological Hyperprolactinemia: Effect of Bromocriptine

1990 ◽  
Vol 51 (3-4) ◽  
pp. 303-305 ◽  
Author(s):  
M. C. Honorati ◽  
P. Travaglini ◽  
B. De Bernardi ◽  
R. Scorza ◽  
C. Hu ◽  
...  
Keyword(s):  
Nk Activity ◽  
Pathological Hyperprolactinemia

Regulation of mouse natural killer (NK) activity by interferon-γ (IFN-γ)

1985 ◽  
Vol 7 (3) ◽  
pp. 327
Author(s):  
F. Velotti ◽  
A. Santoni ◽  
F. Cofano ◽  
S. Landolfo ◽  
M. Piccoli ◽  
...  
Keyword(s):  
Natural Killer ◽  
Interferon Γ ◽  
Nk Activity ◽  
Ifn Γ

Natural killer (NK) activity of cultured S100β-positive T-leukemia cells

1990 ◽  
Vol 59 (1) ◽  
pp. 159-164 ◽  
Author(s):  
Kiyoshi Takahashi ◽  
Tadashi Yoshino ◽  
Tadaatsu Akagi ◽  
Katsuya Miyatani ◽  
Kazuhiko Hayashi ◽  
...  
Keyword(s):  
Natural Killer ◽  
Leukemia Cells ◽  
Nk Activity

Suppressor cells of the human NK activity: Characterization of the cells and mechanism of action

1983 ◽  
Vol 79 (2) ◽  
pp. 265-278 ◽  
Author(s):  
Jussi Tarkkanen ◽  
Eero Saksela ◽  
Eeva Von Willebrand ◽  
Eero Lehtonen
Keyword(s):  
Mechanism Of Action ◽  
Suppressor Cells ◽  
Nk Activity

Prolactin Lowering Effect of Amphetamine in Normoprolactinemic Subjects and in Physiological and Pathological Hyperprolactinemia

1983 ◽  
Vol 15 (09) ◽  
pp. 439-443 ◽  
Author(s):  
V. DeLeo ◽  
S. Cella ◽  
F. Camanni ◽  
A. Genazzani ◽  
E. Müller
Keyword(s):  
Lowering Effect ◽  
Pathological Hyperprolactinemia

P.3.018 Decreased TNF-α, IL-6, and NK activity in obsessive-compulsive disorder

2003 ◽  
Vol 13 ◽  
pp. S361
Author(s):  
D. Denys ◽  
S. Fluitman ◽  
A. Kavelaars ◽  
C. Heijnen ◽  
H.G.M. Westenberg
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Nk Activity ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Tnf Α

scholarly journals Decreased natural killer (NK) activity in patients with myeloproliferative disorders

Cancer ◽  
1989 ◽  
Vol 64 (5) ◽  
pp. 1038-1040 ◽  
Author(s):  
Paul Froom ◽  
Ester Aghai ◽  
Amalia Kinarty ◽  
Nitza Lahat
Keyword(s):  
Natural Killer ◽  
Myeloproliferative Disorders ◽  
Nk Activity

Central interferon-alpha inhibits natural killer cytotoxicity through sympathetic innervation

1993 ◽  
Vol 265 (2) ◽  
pp. R453-R459 ◽  
Author(s):  
S. Take ◽  
T. Mori ◽  
T. Katafuchi ◽  
T. Hori
Keyword(s):  
Natural Killer ◽  
Interferon Alpha ◽  
Viral Infections ◽  
Sympathetic Innervation ◽  
Nk Activity ◽  
Ifn Alpha ◽  
Nk Cytotoxicity ◽  
The Brain ◽  
Natural Killer Cytotoxicity ◽  
Crf System

The brain has been known to produce high levels of interferon-alpha (IFN-alpha) during viral infections. We investigated the central and peripheral mechanisms of the brain IFN-alpha-induced suppression of natural killer (NK) cytotoxicity in the rat. The activity of NK cells in the spleen and the peripheral blood decreased 30-120 min after intracerebroventricular (icv) injection of recombinant human IFN-alpha of > 1,000 U but not after its intraperitoneal injection. This effect was antagonized by pretreatment with icv naltrexone (NLTX). Splenic denervation was observed to completely abolish the IFN-alpha-induced suppression of NK activity, whereas bilateral adrenalectomy did not. Furthermore, this immunosuppression was blocked by an icv injection of an antagonist of corticotropin-releasing factor (CRF), alpha-helical CRF-(9-41). The icv injection of CRF resulted in reduced NK activity, which was not affected by NLTX. The results suggest that brain IFN-alpha activates the CRF system through central opioid receptors and thereby suppresses the NK cytotoxicity predominantly through splenic sympathetic innervation.

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