Quantitative assessment of the neuroendocrine axes and immune system in the setting of the experimental emotional stress, factor model

2015 ◽  
Vol 11 (12) ◽  
pp. 31-42 ◽  
Author(s):  
O.Yu. Mayorov ◽  
◽  
◽  
Keyword(s):  
Immune System ◽  
Emotional Stress ◽  
Quantitative Assessment ◽  
Factor Model ◽  
Stress Factor

Sleep and Covid-19: neurophysiological and biochemical issues

2021 ◽  
Vol 23 (1) ◽  
pp. 22-30
Author(s):  
Yu. V. Boldyreva ◽  
Keyword(s):  
Nervous System ◽  
Immune System ◽  
Circadian Clock ◽  
Elderly People ◽  
Risk Group ◽  
Stress Factor ◽  
Functional Disorders ◽  
Pathology Data

Functional disorders of the nervous system against the background of Covid-19 are reviewed with the emphasis on sleep and circadian clock disorders during the pandemic. The pandemic is regarded as the strong stress factor that affects sleep and the clock. A large risk group consists of elderly people and people with concomitant somatic pathology. Data on the effect of SARS-CoV-2 on other organs and systems, on the functioning of the immune system, are presented.

Multi-stress factor model for cycle lifetime prediction of lithium ion batteries with shallow-depth discharge

2015 ◽  
Vol 279 ◽  
pp. 123-132 ◽  
Author(s):  
Yingzhi Cui ◽  
Chunyu Du ◽  
Geping Yin ◽  
Yunzhi Gao ◽  
Lingling Zhang ◽  
...  
Keyword(s):  
Lithium Ion Batteries ◽  
Factor Model ◽  
Lithium Ion ◽  
Stress Factor ◽  
Shallow Depth ◽  
Lifetime Prediction

scholarly journals Radionuclide activity and the immune system functioning in residents of radiation contaminated areas

2015 ◽  
Vol 6 (2) ◽  
pp. 93-96 ◽  
Author(s):  
V. L. Sokolenko ◽  
S. V. Sokolenko
Keyword(s):  
Immune System ◽  
T Lymphocytes ◽  
Blood Serum ◽  
Emotional Stress ◽  
Cortisol Level ◽  
Relative Number ◽  
System Functioning ◽  
Positive Correlations ◽  
Immune System Functioning ◽  
Radionuclide Activity

The objective of this research is to assess the relation of radioactive contamination degree to immune system functioning, in the absence or presence of additional potential immunosuppressants. To achieve the objective, during the period of 1995–2015 we examined 250 people, students of Cherkasy State University, who lived in the areas of enhanced radiation monitoring before. Also we evaluated the additional impact of the emotional stress caused by examinations on examined students. Indicators of cellular immunity were determined by immunophenotyping and dyeing using Romanowsky-Giemsa method. The level of immunoglobulins in blood serum was determined by radial immunodiffusion (Mancini method). The level of cortisol in blood serum was determined by immunoenzyme method. We have found that in absence of the emotional stress among residents of the areas contaminated with radionuclides, cortisol level remained at the upper limit of homeostatic norm. There is an average positive correlation between the activity of radionuclides in the territories of residence and the level of cortisol. There are marked average positive correlations between the activity of radionuclides and the level of neutrophils, and low positive correlations with the levels of IgG and IgM in blood serum. Average negative correlations between the activity of radionuclides and the following parameters are also observed: absolute and relative number of functionally mature T-lymphocytes with phenotype CD3+, absolute and relative number of their helper subpopulation CD4+, absolute and relative number of natural killer cells with phenotype CD16+; and strong negative correlations with immunoregulatory index CD4+/CD8+. Cortisol level shows the similar correlation with the same parameters, but correlation coefficient is lower. Under conditions of additional stress, caused by emotional load during the examinations, cortisol level significantly increases. This enhanced previously discovered correlations and revealed new ones: average negative correlations between radionuclide activity / cortisol level and expression of pan-T cell marker CD5, medium positive correlations with absolute and relative number of suppressor T-lymphocytes with phenotype CD8+, correlation with the level of serum IgG changes from positive to negative. Additional short-term stress factor combined with chronic influence of low doses of radiation increases the dependence of immunosuppression, caused by radiation contamination of the areas where examined students live, and causes failures in the work of compensatory mechanisms, particularly at the level of serum immunoglobulin products. 

ՀՀ դրամավարկային քաղաքականության արդյունքների վերլուծությունն ու արդյունավետության գնահատումը

2021 ◽  
pp. 171-180
Author(s):  
Hayk Bejanyan ◽  
Lusine Khachikyan
Keyword(s):  
Monetary Policy ◽  
Central Bank ◽  
Statistical Methods ◽  
Quantitative Assessment ◽  
Factor Model ◽  
Graphic Analysis ◽  
The Republic ◽  
The Impact ◽  
Goals And Objectives

The impact of monetary policy on the country's economy is revealed by assessing the effectiveness, which is carried out by analyzing the goals and objectives of the policy. The purpose of the article is to assess the effectiveness of the monetary policy for the RA economy and the compliance of the strategy adopted by the Central Bank with the economic goals of the RA. To achieve this goal, the following issues are resolved in the article: to study the mechanism of the transfer monetary policy of the Republic of Armenia, to analyze the levels of macroeconomic targets registered in the period under review, to compare them to determine the effectiveness of the monetary policy of the Central Bank. The article uses scientific abstraction, historical and logical combination, graphic analysis, economic, mathematical and statistical methods. To complete the analysis, the task was set to develop a consolidated indicator that would allow obtaining a clear quantitative assessment of the effectiveness of MP. The article also proposes a new factor model for assessment of monetary policy in order to provide a quantitative assessment of the effectiveness.

scholarly journals Medical rehabilitation of persons in a chronic emotional stress

2010 ◽  
Vol 9 (4) ◽  
pp. 107-110
Author(s):  
A. A. Zaitsev ◽  
L. V. Barabash ◽  
Ye. F. Levitsky
Keyword(s):  
Immune System ◽  
Chronic Diseases ◽  
Emotional Stress ◽  
Police Officers ◽  
Chronic Prostatitis ◽  
Research Problem ◽  
Medical Rehabilitation ◽  
Military Operations ◽  
New Approach ◽  
Working Out

The research problem wasstudying of influence of a complex physicaland balneal therapies on endokrinno-metabolic processes and immune system of an organismof participants of confrontations with different forms of chronic diseases for the purpose of working out of adequate schemes of regenerativetreatment. 173 police officers, at the age from 22 till 45 years old which were taking part in military operations in the Chechen republicare surveyed. At receiptin a hospital for patients diagnosed following forms of chronic diseases: a chronic prostatitis, chronic холецистити neurologicdisplays of an osteochondrosis. Schemes of stageby-stage rehabilitation have been developed for correction of the revealed infringementswith appointment of base complexes at the first stage of regenerative treatment. On the basis of studying of dynamics of indicators of the endokrinno-metabolic status and a condition of immune system of an organism of participants of confrontations with various forms of chronic diseases the substantiation of the new approach to correction of the poststressful frustration, consisting in stage-by-stage rehabilitation with appointment at the first stage корригирующего a base complex is presented. The carried outcomparative analysis of efficiency of medical actionsspecifies in expediency of application двухэтапного a rehabilitation course (taking into accountconcrete nosological form) for correction of poststressful frustration at participants of operations.

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