Effects of emotional stress on the immune system

1985 ◽  
Vol 20 (2) ◽  
pp. 47-52
Author(s):  
Neal E. Miller
2015 ◽  
Vol 6 (2) ◽  
pp. 93-96 ◽  
Author(s):  
V. L. Sokolenko ◽  
S. V. Sokolenko

The objective of this research is to assess the relation of radioactive contamination degree to immune system functioning, in the absence or presence of additional potential immunosuppressants. To achieve the objective, during the period of 1995–2015 we examined 250 people, students of Cherkasy State University, who lived in the areas of enhanced radiation monitoring before. Also we evaluated the additional impact of the emotional stress caused by examinations on examined students. Indicators of cellular immunity were determined by immunophenotyping and dyeing using Romanowsky-Giemsa method. The level of immunoglobulins in blood serum was determined by radial immunodiffusion (Mancini method). The level of cortisol in blood serum was determined by immunoenzyme method. We have found that in absence of the emotional stress among residents of the areas contaminated with radionuclides, cortisol level remained at the upper limit of homeostatic norm. There is an average positive correlation between the activity of radionuclides in the territories of residence and the level of cortisol. There are marked average positive correlations between the activity of radionuclides and the level of neutrophils, and low positive correlations with the levels of IgG and IgM in blood serum. Average negative correlations between the activity of radionuclides and the following parameters are also observed: absolute and relative number of functionally mature T-lymphocytes with phenotype CD3+, absolute and relative number of their helper subpopulation CD4+, absolute and relative number of natural killer cells with phenotype CD16+; and strong negative correlations with immunoregulatory index CD4+/CD8+. Cortisol level shows the similar correlation with the same parameters, but correlation coefficient is lower. Under conditions of additional stress, caused by emotional load during the examinations, cortisol level significantly increases. This enhanced previously discovered correlations and revealed new ones: average negative correlations between radionuclide activity / cortisol level and expression of pan-T cell marker CD5, medium positive correlations with absolute and relative number of suppressor T-lymphocytes with phenotype CD8+, correlation with the level of serum IgG changes from positive to negative. Additional short-term stress factor combined with chronic influence of low doses of radiation increases the dependence of immunosuppression, caused by radiation contamination of the areas where examined students live, and causes failures in the work of compensatory mechanisms, particularly at the level of serum immunoglobulin products. 


2010 ◽  
Vol 9 (4) ◽  
pp. 107-110
Author(s):  
A. A. Zaitsev ◽  
L. V. Barabash ◽  
Ye. F. Levitsky

The research problem wasstudying of influence of a complex physicaland balneal therapies on endokrinno-metabolic processes and immune system of an organismof participants of confrontations with different forms of chronic diseases for the purpose of working out of adequate schemes of regenerativetreatment. 173 police officers, at the age from 22 till 45 years old which were taking part in military operations in the Chechen republicare surveyed. At receiptin a hospital for patients diagnosed following forms of chronic diseases: a chronic prostatitis, chronic холецистити neurologicdisplays of an osteochondrosis. Schemes of stageby-stage rehabilitation have been developed for correction of the revealed infringementswith appointment of base complexes at the first stage of regenerative treatment. On the basis of studying of dynamics of indicators of the endokrinno-metabolic status and a condition of immune system of an organism of participants of confrontations with various forms of chronic diseases the substantiation of the new approach to correction of the poststressful frustration, consisting in stage-by-stage rehabilitation with appointment at the first stage корригирующего a base complex is presented. The carried outcomparative analysis of efficiency of medical actionsspecifies in expediency of application двухэтапного a rehabilitation course (taking into accountconcrete nosological form) for correction of poststressful frustration at participants of operations.


2019 ◽  
Author(s):  
Johanna Elisha

One of the sexually transmitted diseases that is often talked about among society is HIV (Human Immunodeficiency Virus). HIV is a disease that attacks white blood cells and affects the immune system of an individual. With the absence of vaccines that can cure HIV disease effectively, it causes mental pressure for people infected by HIV, especially in women. The negative stigma from society towards people infected with HIV also adds emotional pressure to people who have HIV. The emotional pressure that found in people who are infected by HIV can lead to depression. To reduce the emotional stress that is found in HIV-positive individuals, the support of people around them is encouraged. One of them is from the closest person, namely a family member. By obtaining the negative stigma from society, for ODHA (people with HIV/ AIDS) it is necessary to have people who can restore their confidence and support them, so ODHA can accept themselves as HIV-positive individuals and avoid emotional stress that can lead to depression. In addition, support from the closest people can encourage people with HIV to have a better prognosis.


2001 ◽  
Vol 120 (5) ◽  
pp. A152-A152
Author(s):  
H SUZUKI ◽  
S NAGAHASHI ◽  
M MIYAZAWA ◽  
M MORI ◽  
H NAGATA ◽  
...  

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