pH and Electromagnetic Dual-Remoted Drug Delivery Based on Bimodal Superparamagnetic Fe3O4@Porous Silica Nanoparticles

2018 ◽  
Author(s):  
Haihua Hu ◽  
◽  
Haopeng Liu ◽  
Dianjun Zhang ◽  
Jianjun Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Silica Nanoparticles ◽  
Porous Silica

scholarly journals Poly(NIPAM- co -MPS)-grafted multimodal porous silica nanoparticles as reverse thermoresponsive drug delivery system

2017 ◽  
Vol 12 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Sushilkumar A. Jadhav ◽  
Valentina Brunella ◽  
Dominique Scalarone ◽  
Gloria Berlier
Keyword(s):  
Drug Delivery ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Porous Silica

scholarly journals Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Nikola Ž. Knežević ◽  
Sanja Milenković ◽  
Danica Jović ◽  
Slavica Lazarevic ◽  
Jasminka Mrdjanović ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Thermogravimetric Analysis ◽  
Drug Release ◽  
Silica Nanoparticles ◽  
Porous Silica ◽  
Targeted Treatment ◽  
Capping Agent ◽  
Ph Responsive ◽  
Tumor Tissues ◽  
Acidic Conditions

Novel nanocomposite containing fullerenol nanoparticles (FNP) and porous silica nanoparticles (PSNs) was constructed and characterized. The capability of FNP to serve as a pore-capping agent and for entrapping 9-aminoacridine (9-AA) inside the pores of the PSN material was also demonstrated. Nitrogen sorption measurements evidence the successful capping of the silica pores while thermogravimetric analysis of FNP loaded PSN indicates the existence of pore-loaded fullerenol molecules. Higher amount of the drug release was noted by exposing the material to weakly acidic conditions in comparison to physiological pH, which may find application in targeted treatment of weakly acidic tumor tissues.

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

Polymer-Grafted Porous Silica Nanoparticles with Enhanced CO2 Permeability and Mechanical Performance

2021 ◽  
Author(s):  
Zongyu Wang ◽  
Hao Chen ◽  
Yangyang Wang ◽  
Jihua Chen ◽  
Mark A. Arnould ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Mechanical Performance ◽  
Porous Silica

Pollen-like silica nanoparticles as a nanocarrier for tumor targeted and pH-responsive drug delivery

Talanta ◽  
2021 ◽  
Vol 231 ◽  
pp. 122402
Author(s):  
Rongrong Jin ◽  
Jiaxi Wang ◽  
Mingxia Gao ◽  
Xiangmin Zhang
Keyword(s):  
Drug Delivery ◽  
Silica Nanoparticles ◽  
Ph Responsive
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