scholarly journals Investigation of frequency characteristics of biological tissues impedance

Radiotekhnika ◽  
2020 ◽  
pp. 186-190
Author(s):  
V.V. Semenets ◽  
V.I. Leonidov
Keyword(s):  
Biological Tissue ◽  
Measurement Method ◽  
Impedance Measurement ◽  
Thermal Exposure ◽  
Biological Tissues ◽  
Isotonic Solution ◽  
Tissue Samples ◽  
Tissue Impedance ◽  
Significant Difference ◽  
Frequency Dependences

The problem of identifying informative signs of biological tissues viability using the impedance measurement method is formulated. At present there is no instrumental base that makes it possible in an operational setting to diagnose the ability of biological tissue to heal itself after injury and damage as a result of thermal exposure, gunshot wound or prolonged compression. It is shown in this article that development of methods and tools for instrumental diagnostics in medical diagnostic practice is an important modern challenge. The results of experimental measurements of impedance characteristics in the frequency range of 20 Hz – 2.0 MHz are presented. The frequency dependences of the modulus of voltage on biological tissues of plant origin are analyzed in its intact state, as well as after exposure of biological tissue samples in a freezer at time intervals from 15 minutes to 2 hours. A comparative analysis of the obtained frequency dependences is carried out. A significant difference between the frequency dependences of the voltage modulus on biological tissues and the frequency dependence of the voltage modulus on an isotonic solution is shown. The concept is introduced that the degree of difference between the frequency distribution of the biological tissue impedance module from the impedance module of an isotonic solution can serve as a criterion for assessing the degree of damage to biological tissue. A conclusion is made about the advisability of developing the impedance measurement method as a method for diagnosing the viability of biological tissue; it is shown that the most promising approach to the development of impedance measurement methods is the analysis of transient processes when biological tissue is disturbed by small electric current pulses.

scholarly journals Electronic devices for studying mechanical properties of biological tissues

2020 ◽  
pp. 40-47
Author(s):  
A. G. Dubko ◽  
R. S. Osipov ◽  
Yu. V. Bondarenko ◽  
O. F. Bondarenko
Keyword(s):  
Mechanical Properties ◽  
Mathematical Models ◽  
Biological Tissue ◽  
Low Cost ◽  
Operation Mode ◽  
Experimental System ◽  
Biological Tissues ◽  
Optimal Operation ◽  
Biocompatible Materials ◽  
Tissue Samples

The paper shows the relevance of studying the mechanical properties of biological tissues and biocompatible materials for solving the problems of general and reconstructive surgery, transplantology, manual therapy, virtual simulation of surgical operations, robotic surgery, etc. The authors present basic information about biological tissue as an object of research and give a brief overview of the devices used for studying the mechanical characteristics of biological tissues. An experimental system for testing deformations of biological tissues and biocompatible materials during compression is described. The system is developed using modern hardware and software, as well as effective technical solutions. The results of the practical use of the developed device are presented and the obtained dependences of the mechanical stress of biological tissue samples on their deformation under pressure are analyzed. The system has high metrological characteristics and low cost, and allows performing all the necessary functions for measuring, processing and visualizing the data. The measurements obtained with this system can help form the recommendations for doctors on choosing the optimal operation mode of medical devices and instruments in each specific case. In addition, the measured data can be used to create mathematical models of biological tissues and biocompatible materials in order to further carry out virtual experiments. In further studies, the authors plan to create the mathematical models of biological tissues based on the finite element method and using the actual values characterizing the tissue, obtained with the developed system.

An Impedance Measurement Method of Solar Panels by Power Converter using PRBS

2020 ◽  
Vol 140 (3) ◽  
pp. 140-147
Author(s):  
Koji Takechi ◽  
Takeshi Yokoi ◽  
Hiroaki Kakigano
Keyword(s):  
Measurement Method ◽  
Impedance Measurement ◽  
Power Converter ◽  
Solar Panels

scholarly journals The Effect of Zingiber officinale on the Spleen Tissue and Antibody Titer of Broiler Chickens

2019 ◽  
Vol 36 (01) ◽  
pp. 046-050
Author(s):  
Alireza Taghdisi ◽  
Sajjad Hejazi
Keyword(s):  
Broiler Chickens ◽  
Zingiber Officinale ◽  
Control Group ◽  
White Pulp ◽  
Broiler Chicks ◽  
Pulp Tissue ◽  
Tissue Samples ◽  
Serum Factors ◽  
Spleen Tissue ◽  
Significant Difference

Introduction Increasing the immune system's function of fighting infectious diseases is very important in the poultry industry. Ginger, scientifically known as Zingiber officinale, belongs to the Zingiberaceae family. The use of ginger in the diet of poultry increases serum levels of superoxide dismutase enzymes and glutathione peroxidase, which are considered to be important antioxidant enzymes. The main objective of the present study is to evaluate the effect of ginger on the spleen tissue of broiler chickens. Material and Methods The specimens comprised 2 groups of 20 Ross breed broiler chicks, for 42 days and were then, examined and tested. The diet was supplemented with 1 g/kg of ginger powder from the beginning of the rearing period. Blood samples of the chicks were randomly collected to measure the levels of hemagglutination (HI). The removed spleens were fixed with 10% formalin buffer. The specimens were cut in 5-micron diameters and stained with hematoxylin and eosin. Results and Conclusion There was a statistically significant difference in the mean of HI blood titers between the chicks in the growth period and final period groups (p < 0.05). The white-pulp tissue samples were more clearly seen in the treatment group than in the control group, and also, it was observed that the wall of the central artery of the white pulp was thicker in the ginger-treated group as compared with the control group. The nutritional value of ginger may vary. Thus, it is necessary to investigate the effect of this plant final on weight gain; the serum factors associated with the metabolic chart, and the response of the immune system to this plant.

Laboratory Specimens and Genetic Privacy: Evolution of Legal Theory

2013 ◽  
Vol 41 (S1) ◽  
pp. 65-68 ◽  
Author(s):  
Michelle Huckaby Lewis
Keyword(s):  
Biomedical Research ◽  
Biological Samples ◽  
Biological Tissue ◽  
Genetic Information ◽  
Legal Theory ◽  
Genetic Privacy ◽  
Tissue Samples

Human biological tissue samples are an invaluable resource for biomedical research designed to find causes of diseases and their treatments. Controversy has arisen, however, when research has been conducted with laboratory specimens either without the consent of the source of the specimen or when the research conducted with the specimen has expanded beyond the scope of the original consent agreement. Moreover, disputes have arisen regarding which party, the researcher or the source of the specimen, has control over who may use the specimens and for what purposes. The purposes of this article are: (1) to summarize the most important litigation regarding the use of laboratory specimens, and (2) to demonstrate how legal theory regarding control of laboratory specimens has evolved from arguments based upon property interests in biological samples to claims that the origins of laboratory specimens have privacy interests in their genetic information that should be protected.

Investigation of Gas Formation Processes in Cotton Fabrics Impregnated with Binary Compositions of Ethyl Silicate - Flame Retardant System

2021 ◽  
Vol 1038 ◽  
pp. 460-467
Author(s):  
Olga Skorodumova ◽  
Olena Tarakhno ◽  
Olena Chebotaryova ◽  
Dmitriy Saveliev ◽  
Fatih Mehmet Emen
Keyword(s):  
Fire Retardant ◽  
Thermal Exposure ◽  
Ethyl Silicate ◽  
Toxic Substances ◽  
Formation Processes ◽  
Tissue Samples ◽  
Textile Materials ◽  
Gas Formation ◽  
Materials Used ◽  
Diammonium Hydrogen

The use of complex fire-retardant coatings based on ethyl silicate gel - diammonium hydrogen phosphate reduces the process of smoke formation during thermal exposure to treated tissue samples, which is promising for improving the fire safety of textile materials. The compositions are easy to obtain, they do not require specific processing conditions, do not contain toxic substances. This allows us to offer developed compositions for fire protection of textile materials used in facilities with a large number of people.

Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples

10.3791/62045 ◽  
2021 ◽  
Author(s):  
Justin A. Courson ◽  
Paul T. Landry ◽  
Thao Do ◽  
Eric Spehlmann ◽  
Pascal J. Lafontant ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Biological Tissue ◽  
Tissue Samples ◽  
Face Scanning ◽  
Block Face ◽  
Scanning Electron

SIMULATION OF SINGLE CHANNEL BIOLOGICAL TISSUE SPECTROSCOPY USING COMSOL MULTIPHYSICS

2015 ◽  
Vol 77 (28) ◽  
Author(s):  
Azmi Abou Basaif ◽  
Nashrul Fazli Mohd Nasir ◽  
Zulkarnay Zakaria ◽  
Ibrahim Balkhis ◽  
Shazwani Sarkawi ◽  
...  
Keyword(s):  
Magnetic Induction ◽  
Biological Tissue ◽  
Single Channel ◽  
Medical Condition ◽  
Biological Tissues ◽  
Comsol Multiphysics ◽  
Accurate Information ◽  
Tissue Properties ◽  
Biological Soft Tissue

The enhanced ability to detect accurate location and measure the depth of a   metal inside a biological tissue is very useful in the assessment of medical condition and treatment. This manuscript proposed a solution via the measurement of the tissue properties using magnetic induction spectroscopy (MIS) method to describe the characterization of biological soft tissue. The objective of this study is to explore the viability of locating embedded metal inside a biological tissue by measuring the differences the biological tissue electrical properties using principle of Magnetic Induction Spectroscopy (MIS). Simulation is done using COMSOL Multiphysics software for accurate information on the involved parameters for both metal and biological tissues. Simulation has confirmed that MIS capable of detecting and locate embedded metal inside a biological tissue.

scholarly journals Impact of secondary particles on microdistribution of deposited dose in biological tissue in the presence of gold and gadolinium nanoparticles under photon beam irradiation

2019 ◽  
Vol 5 (2) ◽  
pp. 109-116
Author(s):  
Ivan A. Konobeev ◽  
Yurij A. Kurachenko ◽  
Igor’ N. Sheino
Keyword(s):  
Biological Tissue ◽  
Biological Tissues ◽  
Photon Beam ◽  
Additional Dose ◽  
Tissue Water ◽  
Secondary Particles ◽  
Photon Sources ◽  
Initial Spectrum ◽  
Photon Spectra ◽  
The Impact

It is experimentally proven that nanoparticles of high-Z materials can be used as radiosensitizers for photon beam therapy. In the authors’ opinion, data available as of today on the impact of secondary particles (electrons, photons and positrons generated in biological tissue by penetrating beam of primary photons) on the distribution of deposited dose during photon beam therapy in the presence of nanoparticles, are insufficient. Investigation of this impact constituted the main goal of this work. Two-stage simulation was performed using Geant4 platform. During the first stage a layer of biological tissue (water) was irradiated by monoenergetic photon sources with energies ranging from 10 keV to 6 MeV. As the result of this modeling spectra of electrons, photons and positrons were obtained at the depth of 5 cm. During the second stage the obtained photon spectra were used to irradiate gold, gadolinium and water nanoparticles. Radial distributions of energy deposited around nanoparticles were obtained as the result of this modeling. Radial DEF (Dose Enhancement Factor) values around nanoparticles of gold and gadolinium positioned in water at the depth of 5 cm were obtained after processing the collected data. Contributions from primary photons and secondary particles (electrons, photons and positrons generated in the layer of water with 5-cm thickness by the penetrating beam of primary photons) in the additional dose deposited around the nanoparticles were calculated as well. It was demonstrated that layer of biological tissue placed between the source of photons and nanoparticles considerably changes the initial spectrum of photons and this change is significant in the analysis of mechanism of radiosensitization of biological tissues by nanoparticles for all energies of photon sources (up to 6 MeV). It was established that interaction of electrons and positrons with nanoparticles does not lead to significant increase of additional dose in the vicinity of their surfaces and can be most likely excluded from consideration in the analysis of radiosensitization mechanism of nanoparticles.

scholarly journals Effect of Glutamine on Apoptosis-inducing Factor Expression and Apoptosis of Glomerular Parietal Epithelial Cells of Cisplatin-exposed Rats

2021 ◽  
Vol 9 (A) ◽  
pp. 367-372
Author(s):  
Ihsan Fahmi Rofananda ◽  
Jusak Nugraha ◽  
Imam Susilo ◽  
Miyayu Soneta Sofyan
Keyword(s):  
Epithelial Cells ◽  
Tissue Samples ◽  
Apoptosis Rate ◽  
Significant Difference ◽  
Parietal Epithelial Cell ◽  
Parietal Epithelial Cells ◽  
Apoptosis Inducing Factor ◽  
Post Hoc ◽  
Nephroprotective Effect ◽  
Test Result

AIM: This study analyzed the nephroprotective effect by examining apoptosis-inducing factor (AIF) expression and apoptosis rate in the glomerular parietal epithelial cell of cisplatin-exposed rats. METHODS: Samples consisted of 30 rats (divided into 3 groups: Group P0 received no treatment, group P1 received a cisplatin injection on the 7th day, and group P2 received glutamine injection on days 1–7 and cisplatin injection on the 7th day). After 72 h, the tissue samples were immunohistochemically processed. AIF expression was measured in an Allred score. The apoptosis rate was measured in apoptotic cells/field of view. Statistical analysis was carried out using JASP Statistics ver. 0.12.0 (p < 0.05). RESULTS: AIF expression values are follows: P0 = 4.89 ± 0.418, P1 = 6.14 ± 0.685, and P2 = 4.95 ± 0.530. The Kruskal–Wallis test result showed a significant difference (p < 0.05) between the groups and Dunn’s post hoc test showed a significant difference between P0 and P1 and between P1 and P2, but no significant difference between P0 and P2. Meanwhile, apoptosis rate values are as follows: P0 = 24.3 ± 9.821, P1 = 123.6 ± 16.008, and P2 = 77.2 ± 10.644. The Kruskal–Wallis test result showed a significant difference (p < 0.05) between the groups, and Dunn’s post hoc test showed a significant difference between P0 and P1, between P1 and P2, and between P0 and P2. CONCLUSION: The expression of AIF and apoptosis of glomerular parietal epithelial cells of the cisplatin-exposed rat has decreased after glutamine treatment.

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