SIMULATION OF SINGLE CHANNEL BIOLOGICAL TISSUE SPECTROSCOPY USING COMSOL MULTIPHYSICS

2015 ◽  
Vol 77 (28) ◽  
Author(s):  
Azmi Abou Basaif ◽  
Nashrul Fazli Mohd Nasir ◽  
Zulkarnay Zakaria ◽  
Ibrahim Balkhis ◽  
Shazwani Sarkawi ◽  
...  

The enhanced ability to detect accurate location and measure the depth of a   metal inside a biological tissue is very useful in the assessment of medical condition and treatment. This manuscript proposed a solution via the measurement of the tissue properties using magnetic induction spectroscopy (MIS) method to describe the characterization of biological soft tissue. The objective of this study is to explore the viability of locating embedded metal inside a biological tissue by measuring the differences the biological tissue electrical properties using principle of Magnetic Induction Spectroscopy (MIS). Simulation is done using COMSOL Multiphysics software for accurate information on the involved parameters for both metal and biological tissues. Simulation has confirmed that MIS capable of detecting and locate embedded metal inside a biological tissue.

2015 ◽  
Vol 73 (6) ◽  
Author(s):  
Zulkarnay Zakaria ◽  
Shazwani Sarkawi ◽  
Jurimah Abdul Jalil ◽  
Ibrahim Balkhis ◽  
Mohamad Aliff Abd Rahim ◽  
...  

Conventional fetal scalp blood sampling (FBS) need an invasive measurement to detect fetal hypoxia in fetus. This paper describe non-invasive technique employing single channel magnetic induction technique. The simulation was done to determine the best range of frequency value to detect biological tissue and tested with different value of conductivity value. 


2021 ◽  
Vol 2071 (1) ◽  
pp. 012039
Author(s):  
Aiman Abdulrahman Ahmed ◽  
Zulkarnay Zakaria ◽  
Marwah Hamood Ali ◽  
Anas Mohd Noor ◽  
Siti Fatimah Binti Abdul Halim ◽  
...  

Abstract Meningitis is a inflammation of the meninges and the most common central nervous system (CNS) due to bacterial infection. Numbers of children who have bacterial meningitis are still high in recent 15 years regardless of the availability of newer antibiotics and preventive strategies. This research focuses on simulation using COMSOL Multiphysics on the design and development of magnetic induction tomography (MIT) system that emphasizes on a single channel rotatable of brain tissue imaging. The purpose of this simulation is to test the capability of the developed MIT system in detecting the change in conductivity and to identify the suitable transmitter-receiver pair and the optimum frequency based on phase shift measurement technique for detecting the conductivity property distribution of brain tissues. The obtained result verified that the performance of the square coil with 12 number of turns (5Tx-12Rx) with 10MHz frequency has been identified as the suitable transmitter-receiver pair and the optimum frequency for detecting the conductivity property distribution of brain tissues.


Biology ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 64
Author(s):  
Arnaud Millet

The mechanosensitivity of cells has recently been identified as a process that could greatly influence a cell’s fate. To understand the interaction between cells and their surrounding extracellular matrix, the characterization of the mechanical properties of natural polymeric gels is needed. Atomic force microscopy (AFM) is one of the leading tools used to characterize mechanically biological tissues. It appears that the elasticity (elastic modulus) values obtained by AFM presents a log-normal distribution. Despite its ubiquity, the log-normal distribution concerning the elastic modulus of biological tissues does not have a clear explanation. In this paper, we propose a physical mechanism based on the weak universality of critical exponents in the percolation process leading to gelation. Following this, we discuss the relevance of this model for mechanical signatures of biological tissues.


1993 ◽  
Vol 15 (3) ◽  
pp. 238-254 ◽  
Author(s):  
Tomy Varghese ◽  
Kevin D. Donohue

Characterization of tissue microstructure from the backscattered ultrasound signal using the spectral autocorrelation (SAC) function provides information about the scatterer distribution in biological tissue. This paper demonstrates SAC capabilities in characterizing periodicities in A-scans due to regularity in the scatterer distribution. The A-scan is modelled as a cyclostationary signal, where the statistical parameters of the signal vary in time with single or multiple periodicities. This periodicity manifests itself as spectral peaks both in the power spectral density (PSD) and in the SAC. Periodicity in the PSD will produce a well defined dominant peak in the cepstrum, which has been used to determine the scatterer spacing. The relationship between the scatterer spacing and the spacing of the spectral peaks is established using a stochastic model of the echo-formation process from biological tissue. The distribution of the scatterers within the microstructure is modelled using a Gamma function, which offers a flexible method of simulating parametric regularity in the scatterer spacing. Simulations of the tissue microstructure for lower orders of regularity indicate that the SAC components reveal information about the scatterer spacing that are not seen in the PSD and the cepstrum. The echo-formation process is tested by simulating microstructure of varying regularity and analyzing their effect on the SAC, PSD and cepstrum. Experimental validation of the simulation results are provided using in vivo scans of the breast and liver tissue that show the presence of significant spectral correlation components in the SAC.


2014 ◽  
Vol 69 (10-11) ◽  
pp. 597-605 ◽  
Author(s):  
A. Wesam Al-Mufti ◽  
Uda Hashim ◽  
Md. Mijanur Rahman ◽  
Tijjani Adam

AbstractThe distribution of electric potential and space charge in a silicon nanowire has been investigated. First, a model of the nanowire is generated taking into consideration the geometry and physics of the nanowire. The physics of the nanowire was modelled by a set of partial differential equations (PDEs) which were solved using the finite element method (FEM). Comprehensive simulation experiments were performed on the model in order to compute the distribution of potential and space charge. We also determined, through simulation, how the characteristic of the nanowire is affected by its dimensions. The characterization of the resulting nanowire, calculated by COMSOL Multiphysics, shows different dimensions and their effect on space charge and electrical potential


2012 ◽  
Author(s):  
Karla K. Gómez ◽  
María L. Del Prado ◽  
M. Cristina Piña ◽  
M. Carmen García de León
Keyword(s):  

Author(s):  
Irene Georgakoudi ◽  
Jason Motz ◽  
Vadim Backman ◽  
George Angheloiu ◽  
Abigail Haka ◽  
...  

2018 ◽  
Vol 12 (4) ◽  
pp. e201800300 ◽  
Author(s):  
Natasha Tomm ◽  
Linda Ahnen ◽  
Helene Isler ◽  
Stefan Kleiser ◽  
Tanja Karen ◽  
...  

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