STRUCTURAL CHARACTERIZATION AND IN VITRO CYTOTOXIC POTENTIAL OF COAL DUST IN A ROMANIAN POWER PLANT

2010 ◽  
Vol 9 (9) ◽  
pp. 1297-1304
Author(s):  
Alice Raducanu ◽  
Aurica Suvergel ◽  
George Darie ◽  
Ileana Rau ◽  
Constantin Grigoriu ◽  
...  
Keyword(s):  
Power Plant ◽  
Structural Characterization ◽  
Coal Dust ◽  
Cytotoxic Potential

Features of antibodies against benzo[a]pyrene formation in workers of coal mines and thermal power plants

2019 ◽  
pp. 9-14
Author(s):  
Ye. G. Polenok ◽  
S. A. Mun ◽  
L. A. Gordeeva ◽  
A. A. Glushkov ◽  
M. V. Kostyanko ◽  
...  
Keyword(s):  
Power Plant ◽  
Thermal Power Plant ◽  
Power Plants ◽  
Reference Group ◽  
Coal Dust ◽  
Thermal Power ◽  
Coal Mines ◽  
Serum Levels ◽  
Thermal Power Plants ◽  
Immune Reactions

Introduction.Coal dust and coal fi ring products contain large amounts of carcinogenic chemicals (specifically benz[a]pyrene) that are different in influence on workers of coal mines and thermal power plants. Specific immune reactions to benz[a]pyrene therefore in these categories of workers can have specific features.Objective.To reveal features of antibodies specifi c to benz[a]pyrene formation in workers of coal mines and thermal power plants.Materials and methods.The study covered A and G class antibodies against benz[a]pyrene (IgA-Bp and IgG-Bp) in serum of 705 males: 213 donors of Kemerovo blood transfusion center (group 1, reference); 293 miners(group 2) and 199 thermal power plant workers (group 3). Benz[a]pyrene conjugate with bovine serum albumin as an adsorbed antigen was subjected to immune-enzyme assay.Results.IgA-Bp levels in the miners (Me = 2.7) did not differ from those in the reference group (Me = 2.9), but in the thermal power plant workers (Me = 3.7) were reliably higher than those in healthy men and in the miners (p<0.0001). Levels of IgG-Bp in the miners (Me = 5.0) appeared to be lower than those in the reference group (Me = 6.4; (p = 0.05). IgG-Bb level in the thermal power plantworkers (Me = 7.4) exceeded the parameters in the healthy donors and the miners (p<0.0001). Non-industrial factors (age and smoking) appeared tohave no influence on specific immune reactions against benz[a]pyrene in the miners and the thermal power plant workers.Conclusions.Specific immune reactions against benz[a]pyrene in the miners and the thermal power plant workers are characterized by peculiarities: the miners demonstrate lower levels of class A serum antibodies to benz[a]pyrene; the thermal power plant workers present increased serum levels of class G antibodies to benz[a]pyrene. These peculiarities result from only the occupational features, but do not depend on such factors as age, smoking and length of service at hazardous production. It is expedient to study specific immune reactions to benz[a]pyrene in workers of coal mines and thermal power plants, to evaluate individual oncologic risk and if malignancies occur.

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies

2018 ◽  
Vol 14 (5) ◽  
pp. 536-548
Author(s):  
Sahar Yousuf ◽  
Khalid M. Khan ◽  
Uzma Salar ◽  
Almas Jabeen ◽  
Shakil Ahmed ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Structural Characterization ◽  
In Vitro Studies ◽  
Environment Friendly

Structural characterization of naphthalene sulfonamides and a sulfonate ester and their in vitro efficacy against Leishmania tarentolae promastigotes

2021 ◽  
Vol 45 (10) ◽  
pp. 4791-4801
Author(s):  
Edward W. Li ◽  
Jade Katinas ◽  
Marjorie A. Jones ◽  
Christopher G. Hamaker
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Leishmania Tarentolae ◽  
Sulfonate Ester

Structural and biological activity analyses of two naphthalene sulfonamides and a naphthalene sulfonate ester.

Structural characterization and immunostimulatory activity in vitro of a glycogen from sea urchin–Strongylocentyotus internedius

2021 ◽  
Vol 258 ◽  
pp. 117701
Author(s):  
Qing-Chi Wang ◽  
Maosheng Wei ◽  
Yang Yue ◽  
Ning Wu ◽  
Jing Wang ◽  
...  
Keyword(s):  
Sea Urchin ◽  
Structural Characterization ◽  
Immunostimulatory Activity

scholarly journals Hemisynthesis and Biological Evaluation of Cinnamylated, Benzylated, and Prenylated Dihydrochalcones from a Common Bio-Sourced Precursor

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 620
Author(s):  
Anne Ardaillou ◽  
Jérôme Alsarraf ◽  
Jean Legault ◽  
François Simard ◽  
André Pichette
Keyword(s):  
Biological Activities ◽  
Biological Evaluation ◽  
Pharmacological Properties ◽  
Cytotoxic Potential ◽  
Naturally Occurring

Several families of naturally occurring C-alkylated dihydrochalcones display a broad range of biological activities, including antimicrobial and cytotoxic properties, depending on their alkylation sidechain. The catalytic Friedel–Crafts alkylation of the readily available aglycon moiety of neohesperidin dihydrochalcone was performed using cinnamyl, benzyl, and isoprenyl alcohols. This procedure provided a straightforward access to a series of derivatives that were structurally related to natural balsacones, uvaretin, and erioschalcones, respectively. The antibacterial and cytotoxic potential of these novel analogs was evaluated in vitro and highlighted some relations between the structure and the pharmacological properties of alkylated dihydrochalcones.

Synthesis of hollow mesoporous ruthenium nanoparticles: evaluation of physico-chemical properties and toxicity

RSC Advances ◽  
2015 ◽  
Vol 5 (97) ◽  
pp. 79616-79623 ◽  
Author(s):  
Sakthivel Ramasamy ◽  
Devasier Bennet ◽  
Sanghyo Kim
Keyword(s):  
Structural Characterization ◽  
Biomedical Application ◽  
Chemical Properties ◽  
Template Method ◽  
Ruthenium Nanoparticles ◽  
Facile Synthesis ◽  
Physico Chemical

Facile synthesis of hollow mesoporous structured Ru-NPs by dual template method, structural characterization and in vitro biophysical and uptake evaluation for biomedical application.

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