Microsatellite variation in a Chinese grouseBonasa sewerzowipopulation: signs of genetic impoverishment?

2003 ◽  
Vol 9 (1) ◽  
pp. 261-266 ◽  
Author(s):  
Jobs Karl Larsson ◽  
Yue-Hua Sun ◽  
Yun Fang ◽  
Gernot Segelbacher ◽  
Jacob Höglund
Genetics ◽  
1996 ◽  
Vol 144 (2) ◽  
pp. 747-756 ◽  
Author(s):  
Paul Sunnucks ◽  
Phillip R England ◽  
Andrea C Taylor ◽  
Dinah F Hales

Abstract Single-locus microsatellite variation correlated perfectly with chromosome number in Sitobion miscanthi aphids. The microsatellites were highly heterozygous, with up to 10 alleles per locus in this species. Despite this considerable allelic variation, only seven different S. miscanthi genotypes were discovered in 555 individuals collected from a wide range of locations, hosts and sampling periods. Relatedness between genotypes suggests only two successful colonizations of Australia. There was no evidence for genetic recombination in 555 S. miscanthi so the occurrence of recent sexual reproduction must be near zero. Thus diversification is by mutation and chromosomal rearrangement alone. Since the aphids showed no sexual recombination, microsatellites can mutate without meiosis. Five of seven microsatellite differences were a single repeat unit, and one larger jump is likely. The minimum numbers of changes between karyotypes corresponded roughly one-to-one with microsatellite allele changes, which suggests very rapid chromosomal evolution. A chromosomal fission occurred in a cultured line, and a previously unknown chromosomal race was detected. All 121 diverse S. near fragariae were heterozygous but revealed only one genotype. This species too must have a low rate of sexual reproduction and few colonizations of Australia.


Genetics ◽  
2000 ◽  
Vol 156 (3) ◽  
pp. 1285-1298 ◽  
Author(s):  
Bret A Payseur ◽  
Michael W Nachman

Abstract Background (purifying) selection on deleterious mutations is expected to remove linked neutral mutations from a population, resulting in a positive correlation between recombination rate and levels of neutral genetic variation, even for markers with high mutation rates. We tested this prediction of the background selection model by comparing recombination rate and levels of microsatellite polymorphism in humans. Published data for 28 unrelated Europeans were used to estimate microsatellite polymorphism (number of alleles, heterozygosity, and variance in allele size) for loci throughout the genome. Recombination rates were estimated from comparisons of genetic and physical maps. First, we analyzed 61 loci from chromosome 22, using the complete sequence of this chromosome to provide exact physical locations. These 61 microsatellites showed no correlation between levels of variation and recombination rate. We then used radiation-hybrid and cytogenetic maps to calculate recombination rates throughout the genome. Recombination rates varied by more than one order of magnitude, and most chromosomes showed significant suppression of recombination near the centromere. Genome-wide analyses provided no evidence for a strong positive correlation between recombination rate and polymorphism, although analyses of loci with at least 20 repeats suggested a weak positive correlation. Comparisons of microsatellites in lowest-recombination and highest-recombination regions also revealed no difference in levels of polymorphism. Together, these results indicate that background selection is not a major determinant of microsatellite variation in humans.


2004 ◽  
Vol 13 (11) ◽  
pp. 3389-3402 ◽  
Author(s):  
D. LUKAS ◽  
B. J. BRADLEY ◽  
A. M. NSUBUGA ◽  
D. DORAN-SHEEHY ◽  
M. M. ROBBINS ◽  
...  

2013 ◽  
Vol 49 (9) ◽  
pp. 945-949 ◽  
Author(s):  
K. I. Afanas’ev ◽  
G. A. Rubtsova ◽  
E. G. Shaikhaev ◽  
L. A. Zhivotovskii

2011 ◽  
Vol 47 (10) ◽  
pp. 1198-1208 ◽  
Author(s):  
S. D. Pavlov ◽  
A. V. Semenova ◽  
G. A. Rubtsova ◽  
K. I. Afanasiev

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