scholarly journals Effects of Chitosan/Nano Selenium Biofilm on Infected Wound Healing in Rats; An Experimental Study

2019 ◽  
Vol 7 (3) ◽  
pp. 284-291
Author(s):  
Abolfazl Abbaszadeh ◽  
Akram Tehmasebi-Foolad ◽  
Asghar Rajabzadeh ◽  
Nasim Beigi-Brojeni ◽  
Leila Zarei
Keyword(s):  
Experimental Study ◽  
Wound Healing ◽  
Infected Wound

Antioxidant and Antibacterial Phytate Hydrogel for MRSA infected Wound Healing

2022 ◽  
pp. 131690
Author(s):  
Xueyun Gong ◽  
Mi Chen ◽  
Bo Lei ◽  
Weidong Xia ◽  
Xingxing Zhang
Keyword(s):  
Wound Healing ◽  
Infected Wound

Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing

2022 ◽  
Author(s):  
Yan Li ◽  
Miao-miao Han ◽  
Yue Cai ◽  
Bing Jiang ◽  
Yuanxin Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Human Health ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Traditional Therapy ◽  
High Toughness ◽  
Pva Hydrogel

The process of wound healing is often accompanied by bacterial infection, which is a serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the resistance of...

scholarly journals Complementary Effect of Non-Persistent Silver Nano-Architectures and Chlorhexidine on Infected Wound Healing

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1215
Author(s):  
Mykola Pernakov ◽  
Maria Laura Ermini ◽  
Oksana Sulaieva ◽  
Domenico Cassano ◽  
Marco Santucci ◽  
...  
Keyword(s):  
Wound Healing ◽  
Infected Wound ◽  
Bacterial Strains ◽  
Efficacy Evaluation ◽  
Complementary Effect ◽  
Macrophages Polarization ◽  
Bacteriological Profile ◽  
Purulent Wound ◽  
The Common

Surgical site infection (SSI) substantially contributes each year to patients’ morbidity and mortality, accounting for about 15% of all nosocomial infections. SSI drastically increases the rehab stint and expenses while jeopardizing health outcomes. Besides prevention, the treatment regime relies on an adequate antibiotic therapy. On the other hand, resistant bacterial strains have currently reached up to 34.3% of the total infections, and this percentage grows annually, reducing the efficacy of the common treatment schemes. Thus, new antibacterial strategies are urgently demanded. Here, we demonstrated in rats the effectiveness of non-persistent silver nano-architectures (AgNAs) in infected wound healing together with their synergistic action in combination with chlorhexidine. Besides the in vivo efficacy evaluation, we performed analysis of the bacteriological profile of purulent wound, histological evaluations, and macrophages polarization quantifications to further validate our findings and elucidate the possible mechanisms of AgNAs action on wound healing. These findings open the way for the composition of robust multifunctional nanoplatforms for the translation of safe and efficient topical treatments of SSI.

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