Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing

2022 ◽  
Author(s):  
Yan Li ◽  
Miao-miao Han ◽  
Yue Cai ◽  
Bing Jiang ◽  
Yuanxin Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Human Health ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Traditional Therapy ◽  
High Toughness ◽  
Pva Hydrogel

The process of wound healing is often accompanied by bacterial infection, which is a serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the resistance of...

A Multifunctional Supramolecular Hydrogel for Infected Wound Healing

2021 ◽  
Author(s):  
Tingting Ding ◽  
Jiajia Qi ◽  
Jingcheng Zou ◽  
Hongxia Dan ◽  
Hang Zhao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Wound Dressings ◽  
Infected Wound ◽  
Supramolecular Hydrogel ◽  
Physical Barriers

Bacterial infection poses a significant threat to wound healing, and the preparation of novel wound dressings is a concern. However, currently reported dressings serve as traditional physical barriers or functioned...

scholarly journals A graphene hybrid supramolecular hydrogel with high stretchability, self-healable and photothermally responsive properties for wound healing

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6367-6373
Author(s):  
Haifeng Zhang ◽  
Shiya Zheng ◽  
Canwen Chen ◽  
Dagan Zhang
Keyword(s):  
Wound Healing ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Supramolecular Hydrogel

The hydrogel demonstrated properties with high stretchability, self-healable and photothermal properties. Notably, photothermal therapy could be established due to its photothermal responsiveness, benefiting infected wound healing.

scholarly journals β-Cyclodextrin/Triclosan Complex-Grafted Methacrylated Glycol Chitosan Hydorgel by Photocrosslinking via Visible Light Irradiation for a Tissue Bio-Adhesive

2021 ◽  
Vol 22 (2) ◽  
pp. 700
Author(s):  
Young Jae Moon ◽  
Sun-Jung Yoon ◽  
Jeung-Hyun Koo ◽  
Yihyun Yoon ◽  
Hye Jun Byun ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Light Irradiation ◽  
Tissue Adhesive ◽  
Proton Nuclear Magnetic Resonance ◽  
Scanning Calorimetry ◽  
Glycol Chitosan

Accelerating wound healing with minimized bacterial infection has become a topic of interest in the development of the new generation of tissue bio-adhesives. In this study, we fabricated a hydrogel system (MGC-g-CD-ic-TCS) consisting of triclosan (TCS)-complexed beta-cyclodextrin (β-CD)-conjugated methacrylated glycol chitosan (MGC) as an antibacterial tissue adhesive. Proton nuclear magnetic resonance (1H NMR) and differential scanning calorimetry (DSC) results showed the inclusion complex formation between MGC-g-CD and TCS. The increase of storage modulus (G’) of MGC-g-CD-ic-TCS after visible light irradiation for 200 s indicated its hydrogelation. The swollen hydrogel in aqueous solution resulted in two release behaviors of an initial burst and sustained release. Importantly, in vitro and in vivo results indicated that MGC-g-CD-ic-TCS inhibited bacterial infection and improved wound healing, suggesting its high potential application as an antibacterial tissue bio-adhesive.

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