scholarly journals Risks to human and animal health related to the presence of moniliformin in food and feed

EFSA Journal ◽  
2018 ◽  
Vol 16 (3) ◽  
Author(s):  
◽  
Helle Katrine Knutsen ◽  
Jan Alexander ◽  
Lars Barregård ◽  
Margherita Bignami ◽  
...  
2014 ◽  
Vol 7 (3) ◽  
pp. 247-255 ◽  
Author(s):  
A. Malachova ◽  
H.P. van Egmond ◽  
F. Berthiller ◽  
R. Krska

Based on the recent scientific opinion published by the EFSA CONTAM panel on the risks to human and animal health related to the presence of nivalenol in food and feed, this article provides an update on the determination of this Fusarium mycotoxin. After a brief introduction into the chemistry of nivalenol, chromatographic methods as well as other approaches are being discussed. Methods for the determination of nivalenol are well established and can be applied for the analysis of cereals, food, feed and biological samples. Accurate quantification of nivalenol is mostly carried out by liquid chromatography coupled with (multi-stage) mass spectrometry (MS) often within a multi-analyte approach. Some novel techniques, such as direct analysis in real time (DART) MS and electrochemical methods, have shown potential to determine nivalenol, but applications for routine measurements are not yet available. None of the currently available analytical methods has been formally validated in interlaboratory validation studies. While a certified calibrant for nivalenol is available, no matrix reference materials have been developed. Due to the scarcity of appropriate antibodies also no rapid immunochemical methods specific for nivalenol have become available.


EFSA Journal ◽  
2018 ◽  
Vol 16 (8) ◽  
Author(s):  
◽  
Helle Katrine Knutsen ◽  
Jan Alexander ◽  
Lars Barregård ◽  
Margherita Bignami ◽  
...  

EFSA Journal ◽  
2017 ◽  
Vol 15 (9) ◽  
Author(s):  
◽  
Helle Katrine Knutsen ◽  
Jan Alexander ◽  
Lars Barregård ◽  
Margherita Bignami ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Natalia Arroyo-Manzanares ◽  
José F. Huertas-Pérez ◽  
Ana M. García-Campaña ◽  
Laura Gámiz-Gracia

Mycotoxins are toxic secondary metabolites produced by different fungi, with different chemical structures. Mycotoxins contaminate food, feed, or raw materials used in their production and cause diseases and disorders in humans and livestock. Because of their great variety of toxic effects and their extreme heat resistance, the presence of mycotoxins in food and feed is considered a high risk to human and animal health. In order to ensure food quality and health consumers, European legislation has set maximum contents of some mycotoxins in different matrices. However, there are still some food commodities susceptible to fungal contamination, which were not contemplated in this legislation. In this context, we have developed new analytical techniques for the multiclass determination of mycotoxins in a great variety of food commodities (some of them scarcely studied), such as cereals, pseudocereals, cereal syrups, nuts, edible seeds, and botanicals. Considering the latest technical developments, ultrahigh performance liquid chromatography coupled to tandem mass spectrometry has been chosen as an efficient, fast, and selective powerful analytical technique. In addition, alternative sample treatments based on emerging methodologies, such as dispersive liquid-liquid microextraction and QuEChERS, have been developed, which allow an increased efficiency and sample throughput, as well as reducing contaminant waste.


EFSA Journal ◽  
2017 ◽  
Vol 15 (7) ◽  
Author(s):  
◽  
Helle‐Katrine Knutsen ◽  
Jan Alexander ◽  
Lars Barregård ◽  
Margherita Bignami ◽  
...  

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