scholarly journals Species difference in bioavailability of oral drug controlled release formulation

2017 ◽  
Vol 32 (5) ◽  
pp. 372-380
Author(s):  
Hiromu Kondo
Keyword(s):  
Controlled Release ◽  
Species Difference ◽  
Oral Drug ◽  
Release Formulation ◽  
Drug Controlled Release ◽  
Controlled Release Formulation

Optimization Study to Develop Once-a-day Controlled Release Formulation of Metoclopramide with Predictable Design Space

1970 ◽  
Vol 1 (1) ◽  
pp. 71-76
Author(s):  
Rajesh Dubey ◽  
Udaya K. Chowdary ◽  
Venkateswarlu V.
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Design Space ◽  
Release Kinetics ◽  
Release Profile ◽  
Release Formulation ◽  
Linear Effect ◽  
Controlled Release Formulation ◽  
The Difference ◽  
Face Centered

A controlled release formulation of metoclopramide was developed using a combination of hypromellose (HPMC) and hydrogenated castor oil (HCO). Developed formulations released the drug over 20 hr with release kinetics following Higuchi model. Compared to HCO, HPMC showed significantly higher influence in controlling the drug release at initial as well as later phase. The difference in the influence can be explained by the different swelling and erosion behaviour of the polymers. Effect of the polymers on release was optimized using a face-centered central composite design to generate a predictable design space. Statistical analysis of the drug release at various levels indicated a linear effect of the polymers’ levels on the drug release. The release profile of formulations containing the polymer levels at extremes of their ranges in design space was found to be similar to the predicted release profile

scholarly journals Controlled release formulation of an anti-depression drug based on a L-phenylalanate-zinc layered hydroxide intercalation compound

2017 ◽  
Vol 105 ◽  
pp. 35-44 ◽  
Author(s):  
Norhayati Hashim ◽  
Sharifah Norain Mohd Sharif ◽  
Illyas Md Isa ◽  
Shahidah Abdul Hamid ◽  
Mohd Zobir Hussein ◽  
...  
Keyword(s):  
Controlled Release ◽  
Intercalation Compound ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Zinc Layered Hydroxide

Using a reactive emulsifier to construct simple and convenient nanocapsules loaded with lambda-cyhalothrin to achieve efficient foliar delivery and insecticidal synergies

Nanoscale ◽  
2021 ◽  
Author(s):  
Jian Luo ◽  
Yue Gao ◽  
Yukun Liu ◽  
Jiang Du ◽  
Da-xia Zhang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Pest Control ◽  
Release Formulation ◽  
Controlled Release Formulation ◽  
Lambda Cyhalothrin ◽  
Complicated Process ◽  
Convenient Preparation ◽  
Cost Limit

Nanocapsules are a promising controlled release formulation for foliar pest control. However, the complicated process and high cost limit widespread use in agriculture, so a simpler and more convenient preparation...

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