Early induction and augmentation of parasitic antigen-specific antibody-producing B lymphocytes in the non-Peyer s patch region of the small intestine

10.2741/a253 ◽  
1998 ◽  
Vol 3 (1) ◽  
pp. a58-65 ◽  
Author(s):  
Ching-Hua Wang
Keyword(s):  
Small Intestine ◽  
B Lymphocytes ◽  
Specific Antibody

Immune disorders of the gastrointestinal tract

2010 ◽  
pp. 2244-2256
Author(s):  
D.J. Unsworth
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
B Lymphocytes ◽  
Lamina Propria ◽  
Thoracic Duct ◽  
Lymphoid Tissue ◽  
Plasma Cells ◽  
Immunoglobulin A ◽  
Systemic Circulation ◽  
Lymphoid Follicles

The gastrointestinal tract is protected by gut-associated lymphoid tissue that provides an environment where interaction occurs between luminal antigen and specially adapted immune tissue in Peyer’s patches (small intestine only) or lymphoid follicles. T and B lymphocytes primed in the gut migrate into the systemic circulation via the thoracic duct but home preferentially to the lamina propria of the intestine. Plasma cells of the lamina propria secrete immunoglobulin A as a dimer linked by a joining peptide....

Immunophenotype of the inflammatory response in the central and enteric nervous systems of cockatiels (Nymphicus hollandicus) experimentally infected with parrot bornavirus 2

2022 ◽  
pp. 030098582110691
Author(s):  
Jeann Leal de Araújo ◽  
Raquel R. Rech ◽  
Aline Rodrigues-Hoffmann ◽  
Paula R. Giaretta ◽  
Cinthya Cirqueira ◽  
...  
Keyword(s):  
Small Intestine ◽  
T Lymphocytes ◽  
B Lymphocytes ◽  
Inflammatory Infiltrate ◽  
Homogeneous Distribution ◽  
Nymphicus Hollandicus ◽  
Inflammatory Infiltrates ◽  
Cellular Immune ◽  
Proventricular Dilatation Disease ◽  
The Brain

Proventricular dilatation disease is a lethal disease of psittacine birds. In this study, we characterized the local cellular immune response in the brain, proventriculus, and small intestine of 27 cockatiels ( Nymphicus hollandicus) experimentally infected with parrot bornavirus 2 (PaBV-2). Perivascular cuffs in the brain were composed of CD3+ T-lymphocytes and Iba1+ macrophages/microglia in most cockatiels (n = 26). In the ganglia of the proventriculus, CD3+ T-lymphocytes (n = 17) and Iba1+ macrophages (n = 13) prevailed. The ganglia of the small intestine had a more homogeneous distribution of these leukocytes, including PAX5+ B-lymphocytes (n = 9), CD3+ T-lymphocytes (n = 8), and Iba1+ macrophages (n = 8). Our results indicate that perivascular cuffs in the brain and the inflammatory infiltrate in the proventriculus of PaBV-2-infected cockatiels is predominately composed of T-lymphocytes, while the inflammatory infiltrates in the ganglia of the small intestine are characterized by a mixed infiltrate composed of T-lymphocytes, B-lymphocytes, and macrophages.

scholarly journals B-lymphocyte reconstitution after repeated rituximab treatment in a child with steroid-dependent autoimmune hemolytic anemia

2011 ◽  
Vol 3 (4) ◽  
pp. 28 ◽  
Author(s):  
Annelieke A.A. Van der Linde ◽  
Ellen J.H. Schatorjé ◽  
Annemieke M. Van der Weij ◽  
Eugenie F.A. Gemen ◽  
Esther De Vries
Keyword(s):  
B Lymphocytes ◽  
Hemolytic Anemia ◽  
Antibody Production ◽  
Specific Antibody ◽  
Autoimmune Hemolytic Anemia ◽  
B Lymphocyte ◽  
Lymphocyte Subpopulations ◽  
Steroid Dependent ◽  
Specific Antibody Production

We report the detailed long-term reconstitution of B-lymphocyte subpopulations, immunoglobulins, and specific antibody production after two courses of rituximab in a young, previously healthy girl with steroid-dependent autoimmune hemolytic anemia. B-lymphocyte subpopulations were surprisingly normal directly after reconstitution. However, there was a slower reconstitution after the second rituximab course, especially of non-switched and switched memory B-lymphocytes, and a temporary decline in IgM below age-matched reference values.

Enteroantigen (eAg)-binding B lymphocytes in the mouse - phenotype, distribution, function and eAg-specific antibody secretion

Apmis ◽  
2013 ◽  
Vol 122 (7) ◽  
pp. 616-627 ◽  
Author(s):  
Freja Albjerg Venning ◽  
Mette Louise Trempenau ◽  
Esben Schmidt ◽  
Mogens Helweg Claesson
Keyword(s):  
Distribution Function ◽  
B Lymphocytes ◽  
Specific Antibody ◽  
Mouse Phenotype ◽  
Phenotype Distribution ◽  
Antibody Secretion

scholarly journals ACTIVATION OF T AND B LYMPHOCYTES IN VITRO

1974 ◽  
Vol 139 (1) ◽  
pp. 24-43 ◽  
Author(s):  
Dieter Armerding ◽  
David H. Katz
Keyword(s):  
B Lymphocytes ◽  
Specific Antibody ◽  
Cell Function ◽  
Sheep Erythrocyte ◽  
Biological Action ◽  
Antibody Responses ◽  
Secondary Antibody ◽  
Protein Conjugates ◽  
Adjuvant Effects

The present studies were undertaken to analyze the nature of the effect of bacterial lipopolysaccharide (LPS) on antibody production in vitro. We have done this by making comparative studies of the effects of LPS on in vitro primary and secondary antibody responses to soluble hapten-protein conjugates and to particulate and soluble sheep erythrocyte antigens. The results obtained demonstrate that the biological action of LPS in vitro may be predominantly manifested on the function of B lymphocytes or T lymphocytes depending on the conditions employed. In the absence of antigen, LPS appears to act primarily on B lymphocytes. In the presence of antigen, however, the data presented here show that LPS significantly influences specific helper T-cell function and it is this latter influence that is predominantly responsible for the adjuvant effects of LPS on antigen-specific antibody responses.

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