Response and adaptation of skeletal muscle to exercise - the role of reactive oxygen species

10.2741/2431 ◽  
2007 ◽  
Vol 12 (12) ◽  
pp. 4826 ◽  
Author(s):  
Andreas Michael Niess
Keyword(s):  
Reactive Oxygen Species ◽  
Skeletal Muscle ◽  
Reactive Oxygen ◽  
Oxygen Species

scholarly journals Role of reactive oxygen species in contraction-mediated glucose transport in mouse skeletal muscle

2006 ◽  
Vol 575 (1) ◽  
pp. 251-262 ◽  
Author(s):  
Marie E. Sandström ◽  
Shi-Jin Zhang ◽  
Joseph Bruton ◽  
José P. Silva ◽  
Michael B. Reid ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Skeletal Muscle ◽  
Glucose Transport ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Mouse Skeletal Muscle

Age and sex differences in human skeletal muscle: Role of reactive oxygen species

2000 ◽  
Vol 33 (3) ◽  
pp. 287-293 ◽  
Author(s):  
O. Pansarasa ◽  
L. Castagna ◽  
B. Colombi ◽  
J. Vecchiet ◽  
G. Felzani ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Skeletal Muscle ◽  
Sex Differences ◽  
Human Skeletal Muscle ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Age And Sex

Modulation of glucose transport in skeletal muscle by reactive oxygen species

2007 ◽  
Vol 102 (4) ◽  
pp. 1671-1676 ◽  
Author(s):  
Abram Katz
Keyword(s):  
Reactive Oxygen Species ◽  
Skeletal Muscle ◽  
Glucose Transport ◽  
Reactive Oxygen ◽  
Convincing Evidence ◽  
Oxygen Species ◽  
Carbohydrate Utilization ◽  
Muscle Glucose Transport ◽  
Amp Activated Protein Kinase

Glucose transport is an essential physiological process that is characteristic of all eukaryotic cells, including skeletal muscle. In skeletal muscle, glucose transport is mediated by the GLUT-4 protein under conditions of increased carbohydrate utilization. The three major physiological stimuli of glucose transport in muscle are insulin, exercise/contraction, and hypoxia. Here, the role of reactive oxygen species (ROS) in modulating glucose transport in skeletal muscle is reviewed. Convincing evidence for ROS involvement in insulin- and hypoxia-mediated transport in muscle is lacking. Recent experiments, based on pharmacological and genetic approaches, support a role for ROS in contraction-mediated glucose transport. During contraction, endogenously produced ROS appear to mediate their effects on glucose transport via AMP-activated protein kinase.

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