Onyx liquid embolic system (LES): an underestimated tool in the management of peripheral bleedings

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Anna Maria Ierardi ◽  
Marco Femia ◽  
Mario Petrillo ◽  
Salvatore Alessio Angileri ◽  
Tal Hörer ◽  
...  
Keyword(s):  
Interventional Radiology ◽  
Physical Properties ◽  
Vinyl Alcohol ◽  
Interventional Procedures ◽  
Embolic Agent ◽  
Emergency Setting ◽  
Ethylene Vinyl Alcohol ◽  
Bleeding Management ◽  
Liquid Embolic ◽  
Onyx Copolymer

Ethylene vinyl alcohol or Onyx copolymer (Medtronic) is an embolization agent increasingly used in peripheral interventional radiology. The Onyx Liquid Embolic System (LES) offers a liquid, non-adhesive, non-absorbable, injectable and permanent embolic agent with an indication for neuro-interventional procedures. Due to its physical properties, Onyx has more embolic predictability than other currently available liquid agents, and seems to have great potential in endovascular bleeding management, especially for non-coagulated patients. The aim of this brief review is to analyze the advantages of Onyx in the emergency setting on the basis of evidence in the current literature.

scholarly journals Single institutional experience of peripheral applications of a liquid embolic agent: Ethylene Vinyl Alcohol Copolymer

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Abhijit L. Salaskar ◽  
Faezeh Razjouyan ◽  
Alexander L. Cho ◽  
Rishi R. Sood ◽  
Andrew Akman ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Embolic Agent ◽  
Ethylene Vinyl Alcohol ◽  
Ethylene Vinyl Alcohol Copolymer ◽  
Liquid Embolic ◽  
Institutional Experience ◽  
Liquid Embolic Agent

Transcatheter Embolization of a Pancreatic Pseudoaneurysm Using a New Liquid Embolic Agent, Ethylene Vinyl Alcohol Copolymer (Onyx)

Pancreas ◽  
2009 ◽  
Vol 38 (1) ◽  
pp. 110-112 ◽  
Author(s):  
Antonia Brox Jiménez ◽  
Pablo Parra Membrives ◽  
Daniel Díaz Gómez ◽  
José González Herráez ◽  
Jorge Haurie Girelli ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Transcatheter Embolization ◽  
Embolic Agent ◽  
Ethylene Vinyl Alcohol ◽  
Ethylene Vinyl Alcohol Copolymer ◽  
Liquid Embolic ◽  
Liquid Embolic Agent

Initial experience with the new ethylene vinyl alcohol copolymer based liquid embolic agent Menox in the endovascular treatment of cerebral arteriovenous malformations

2019 ◽  
Vol 11 (10) ◽  
pp. 1040-1044 ◽  
Author(s):  
Stanimir Sirakov ◽  
Alexander Sirakov ◽  
Krasimir Minkin ◽  
Marin Penkov ◽  
Kristian Ninov ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Vinyl Alcohol ◽  
Arteriovenous Malformations ◽  
Embolic Agent ◽  
Initial Experience ◽  
Cerebral Arteriovenous Malformations ◽  
Ethylene Vinyl Alcohol ◽  
Arteriovenous Shunts ◽  
Liquid Embolic

Background and PurposeLiquid embolic agents (LEAs) are the determinant tool for successful embolization of cranial arteriovenous shunts. There are few currently available LEAs. The aim of the study was to summarize our initial experience with a recently introduced non-adhesive ethylene vinyl alcohol (EVOH) copolymer based LEA (Menox 18) in the endovascular treatment of cerebral arteriovenous malformations.MethodsFrom April 2018 to November 2018, 24 patients harboring cerebral arteriovenous malformations underwent endovascular embolization with Menox 18. Clinical features, angiographic results, procedural details, complications, and follow-up details were prospectively collected and retrospectively analyzed.ResultsCurative embolization in one endovascular session was achieved in 14/24 (58.3%) of the treated patients. Partial embolization was achieved in 10 patients (42.6%) in whom staged treatment with radiosurgery or microsurgical resection was planned. No mortality was recorded in our series. Clinical complications after embolization occurred in 1/24 (4.66%) patients. No technical complications were notedConclusionsOur pilot study suggests that the Menox embolization system offers similar technical and clinical results in comparison with the other currently available LEAs. Further studies with larger cohorts and long term follow-up data are needed to fully evaluate its efficacy

A mixture of ethylene vinyl alcohol copolymer and ethanol yielding a nonadhesive liquid embolic agent to treat cerebral arteriovenous malformations: initial clinical experience

2002 ◽  
Vol 97 (4) ◽  
pp. 881-888 ◽  
Author(s):  
Jun-Ichiro Hamada ◽  
Yutaka Kai ◽  
Motohiro Morioka ◽  
Kiyoshi Kazekawa ◽  
Yasuji Ishimaru ◽  
...  
Keyword(s):  
Clinical Experience ◽  
Vinyl Alcohol ◽  
Arteriovenous Malformations ◽  
Embolic Agent ◽  
Ethanol Mixture ◽  
Content Type ◽  
Ethylene Vinyl Alcohol ◽  
Liquid Embolic ◽  
Liquid Embolic Agent ◽  
Fine Print

Object. The authors report their clinical experience with their new nonadhesive liquid embolic agent, an ethylene vinyl alcohol copolymer (EVAL)/ethanol mixture, to treat arteriovenous malformations (AVMs). Methods. Between June 1995 and April 2001, 57 patients with confirmed AVMs underwent embolization of their lesions with the EVAL/ethanol mixture. In 87 procedures consisting of one to three stages, the authors embolized 185 feeding arteries to occlude as much of the AVM as possible. Repeated injections under fluoroscopic control could be performed smoothly without encountering cementing of the catheter to the vessel wall. Among the 87 embolizations undertaken in 57 patients, seven procedures (8%) in six patients produced new postembolization symptoms. Resolution of these symptoms occurred within hours or days after four of the seven procedures; permanent neurological deficits remained after the other three procedures (3.4%). Of the 57 patients, three underwent postembolization radiosurgery, and 54 underwent radical treatment with microsurgical extirpation. Histopathological examination of the 54 specimens disclosed mild inflammation within the embolized lumen without inflammatory reactions in the media or adventitia. Follow-up angiograms obtained 3 years after radiosurgery was administered showed that in all three patients treated in this fashion the nidus had completely disappeared. Conclusions. The EVAL/ethanol mixture is handled easily and appears to be an effective and safe agent for preoperative embolization of AVMs.

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