Comparative study of single dose preoperative antibiotics versus preoperative and postoperative antibiotics in laparoscopic appendicectomy for uncomplicated appendicitis in rural hospital

2021 ◽  
Vol 19 (3) ◽  
pp. 85-89
Author(s):  
Keyword(s):  
Single Dose ◽  
Comparative Study ◽  
Rural Hospital ◽  
Laparoscopic Appendicectomy ◽  
Uncomplicated Appendicitis ◽  
Preoperative Antibiotics

scholarly journals Comparative study of single dose preoperative antibiotics versus both preoperative and postoperative antibiotics in laparoscopic appendicectomy for nonperforated appendicitis

2017 ◽  
Vol 4 (9) ◽  
pp. 3092
Author(s):  
Himabindu Bangaru ◽  
Varun V. Gaiki ◽  
M. V. Ranga Reddy
Keyword(s):  
Single Dose ◽  
Surgical Site Infection ◽  
Hospital Stay ◽  
Prophylactic Antibiotics ◽  
Postoperative Hospital Stay ◽  
Laparoscopic Appendicectomy ◽  
Site Infection ◽  
Significant Difference ◽  
Group A ◽  
Preoperative Antibiotics

Background: Antibiotics are being administered both preoperatively and postoperatively even in uncomplicated nonperforated appendicitis. Studies regarding role of postoperative antibiotics in laparoscopic appendicectomy for nonperforated appendicitis are sparse. The aim of the study is therefore to study the efficacy of single dose preoperative antibiotics versus both preoperative and postoperative antibiotics in reducing surgical site infection in laparoscopic appendicectomy for uncomplicated nonperforated acute appendicitis.Methods: This is a prospective study done in general surgery department at Malla Reddy institute of medical sciences from September to April 2016.162 patients with nonperforated appendicitis were randomly allocated into two groups. 80 patients in Group A were given single dose of preoperative prophylactic antibiotics. No further antibiotics were given. 82 patients in Group B were given both preoperative and postoperative antibiotics. Postoperative surgical site infection and duration of postoperative hospital stay were compared between both groups. Statistical analysis was done using ANOVA, Fisher’s Exact test and Chi-square test wherever necessary.Results: There was no significant difference in the rate of surgical site infection in both groups. The mean duration of postoperative hospital stay was shorter in preoperative antibiotics only group (Group A). Age and gender had no significant association with surgical site infection. There was no deep incisional or organ space infection in this study.Conclusions: Single dose prophylactic antibiotics would be sufficient in cases of laparoscopic appendicectomy for simple uncomplicated nonperforated acute appendicitis. Postoperative antibiotic administration would not be necessary in these cases.

scholarly journals Antimicrobial Therapy in Preventing Wound Infection Following Appendicectomy in Uncomplicated Appendicitis: A Comparative Study Between Single Dose And Multiple Doses In Adults

2019 ◽  
Vol 19 (1) ◽  
pp. 17-20
Author(s):  
Mohammad Ashraf Uddin Khan ◽  
Md Alamgir Hossain Sikder ◽  
Arif Salam Khan ◽  
Md Ashiqur Rahman ◽  
Ahmed Sarni Al Hasan ◽  
...  
Keyword(s):  
Single Dose ◽  
Comparative Study ◽  
Wound Infection ◽  
Length Of Hospital Stay ◽  
Control Group ◽  
Study Group ◽  
College Hospital ◽  
Medical College ◽  
Uncomplicated Appendicitis ◽  
And Control

Objectives: To find out the efficacy of single dose antibiotic vs multiple dosesin preventing wound infection following appendicectomy for uncomplicated appendicitis. Methods: A prospective comparative study was conducted in the Department of Surgery, Chittagong Medical college Hospital from January'2009 to June'2009. 100 patients with uncomplicated appendicitis who underwent appendicectomy during that period were included in this study. Among them 50 cases were included in study group ·(SG) who were given only single dose of combination drugs ( lnj. Cefuroxime + lnj. Metronidazole).ln rest of the 50 cases (CG), antibiotics were continued for 7 days postoperatively. Result: Maximum incidence of acute appendicitis was in the 2nd and 3rd decade of life with male preponderance .Rate of wound infection in the study group and control group was 4% and 2% respectively which was not statistically significant .The duration of antibiotic therapy had no significant effect on the length of hospital stay between the two groups ; 2.48 days vs 2.9 days [mean + s.d. 69.6 # 16.8 hours ] in the study and control group respectively, though treatment cost was higher in control group in comparison to the study group . Conclusion: Single dose of preoperative antibiotics is adequate for prevention of postoperative wound infection following appendicectomy for uncomplicated appendicitis. Journal of Surgical Sciences (2015) Vol. 19 (1) : 17-20

scholarly journals 465 No Role for Postoperative Antibiotics in Uncomplicated Appendicitis

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
N Ayoub ◽  
Y Tryliskyy ◽  
M K Baig
Keyword(s):  
Wound Infection ◽  
P Value ◽  
Nice Guidelines ◽  
Uncomplicated Appendicitis ◽  
Perforated Appendix ◽  
Group A ◽  
Preoperative Antibiotics ◽  
Group B ◽  
Variable Practice

Abstract Introduction Several studies have shown benefit from use of preoperative antibiotics in reducing postoperative infection after appendectomy as well as efficacy of postoperative antibiotics in complicated appendicitis (defined as perforated appendix or presence of pus in peritoneum). While for uncomplicated appendicitis, several studies showed no benefit from antibiotics postoperatively but there are no clear NICE guidelines till now and so surgeons have different practice based on their preferences. Method This study included patients who had appendectomy for uncomplicated appendicitis in Worthing hospital from 1st July 2019 till 30th June 2020. The end point was 30-day follow up postoperatively for wound infection or collection. Results 90 patients were admitted with uncomplicated appendicitis with age 6-80 years (mean of 31.3). 46 patients (51%) did not receive postoperative antibiotics (group A) and 44 (49%) received postoperative antibiotics (group B) with a variable practice from one dose to 8-day course. postoperatively, only 1 patient (2.1%) in group A developed wound infection requiring drainage while none in group B developed complications (p-value=1). Conclusions Administration of postoperative antibiotics in uncomplicated appendicitis showed no superiority over non-administration. in addition, they add extra cost on NHS. So, their routine use postoperatively is not recommended, however, larger studies are required to confirm this.

scholarly journals A Comparative Study of Fractionated Versus Single Dose Injection for Spinal Anesthesia During Cesarean Section in Patients with Pregnancy-Induced Hypertension

2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Alfan Mahdi Nugroho ◽  
Adhrie Sugiarto ◽  
Susilo Chandra ◽  
Laras Lembahmanah ◽  
Rafidya Indah Septica ◽  
...  
Keyword(s):  
Single Dose ◽  
Cesarean Section ◽  
Comparative Study ◽  
Spinal Anesthesia ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Dose Injection
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