Histomorphologic study of upper gastrointestinal tract endoscopic biopsies with special reference to neoplastic lesions

2020 ◽  
Vol 15 (3) ◽  
pp. 36-39
Author(s):  
Sanjana Suvarna ◽  
Keyword(s):  
Gastrointestinal Tract ◽  
Special Reference ◽  
Upper Gastrointestinal Tract ◽  
Endoscopic Biopsies ◽  
Neoplastic Lesions ◽  
Upper Gastrointestinal

scholarly journals Histopathological Study of Upper Gastrointestinal Tract Endoscopic Biopsies

2019 ◽  
Vol 6 (1) ◽  
pp. 42-46
Author(s):  
Mosammat Suchana Nazrin ◽  
Nur E Jannatul Ferdous ◽  
Madhusudan Saha ◽  
Fahmi Iqbal Rabbi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Gastrointestinal Tract ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Upper Gastrointestinal Tract ◽  
North East ◽  
Endoscopic Biopsies ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions ◽  
Upper Gastrointestinal

Background: Diseases of gastrointestinal tract are a major cause of morbidity and mortality. Objective: This study was carried out to determine the spectrum of histopathological lesions of upper gastrointestinal tract. Methodology: This retrospective study was conducted in the Department of Pathology at North East Medical College, Sylhet, Bangladesh during a 36 months period from January 2013 to December 2015. Endoscopies were performed using Olympus 150, forward viewing upper GI endoscope. The biopsy specimens received were fixed in 10.0% formalin and routinely processed in Haematoxyline & Eosin stain. Results: The present study included 135 endoscopic biopsies. The mean age with SD of the study population was 53.20±16.09 years. Among 53 cases of esophageal biopsies 8(15.08%) cases showed non-neoplastic lesions and 45(84.92%) cases were neoplastic of which 39(73.6%) cases and 6(11.32%) cases were squamous cell carcinoma and adenocarcinoma respectively. Among 6 cases of gastro esophageal junction biopsies 3(50%) cases showed non-neoplastic lesions and 3(50%) were neoplastic, of which 2(33.33%) were adenocarcinoma and 1(16.67%) were squamous cell carcinoma. Among 61 cases of stomach biopsies 34(55.74%) showed non-neoplastic lesions and 27(44.26%) were neoplastic, of which 1(1.64%) case was adenoma and 25(40.98%) were adenocarcinoma. Among 15 cases of duodenal biopsies 13(86.67%) cases showed non-neoplastic lesions and 2(13.33%) were neoplastic one of which was adenocarcinoma (6.67%). Among 135 cases endoscopist reported 82(60.74%) cases as neoplastic and 53(39.26%) as non-neoplastic, whereas histopathology revealed 77(57.03%) cases neoplastic and 58(42.97%) cases non-neoplastic. Conclusion: Common site of upper GIT endoscopic biopsy is stomach which are mostly neoplastic lesion; however, most common malignancy is squamous cell carcinoma of the oesophagus. Journal of Current and Advance Medical Research 2019;6(1):42-46

scholarly journals Prospective Study on Histopathological Spectrum of Upper Gastrointestinal Tract Lesions in a Teaching Hospital of Southern India

2020 ◽  
Author(s):  
Eslavath Aruna ◽  
V Kalyan Chakravarthy
Keyword(s):  
Gastrointestinal Tract ◽  
Histopathological Examination ◽  
Tissue Sample ◽  
Age Groups ◽  
Upper Gastrointestinal Tract ◽  
Female Ratio ◽  
Inflammatory Conditions ◽  
Endoscopic Biopsies ◽  
Neoplastic Lesions ◽  
Upper Gastrointestinal

Introduction: The Upper Gastrointestinal Tract (UGIT) disorders are quite common in routine clinical practice and have high degree of morbidity and mortality. They can be studied by collecting tissue sample by way of fiberoptic endoscope and by subjecting the tissue to histopathological examination. Aim: To study the spectrum of histopathological lesions of UGIT lesions by endoscopy. Materials and Methods: This was a prospective observational study done in the Department of Pathology at PSIMS, Chinna Avutapalli, Andhra Pradesh, India, over a period of one year from March 2019 to February 2020 on 160 endoscopic biopsies. All UGIT endoscopic biopsies received were examined histopathologically. The data was entered into excel sheets and percentages and ratios were calculated. Results: Lesions of UGIT were more common in the age groups of 31 to 50 years and the male to female ratio was 1.9:1. The patient age ranged from 20 years to 78 years. Stomach was the common site for UGIT endoscopic biopsies i.e., 80 (50%) followed by oesophagus 50 (31.2%) and then duodenum 30 (18.7%). At all three sites, non-neoplastic lesions predominated over neoplastic lesions. The gastric malignancies were more common in antral and pyloric regions. Conclusion: Males in the fourth and fifth decades are more prone for UGIT lesions with predominance of chronic non-specific inflammatory conditions as compared to neoplastic conditions. Malignancy within the stomach, more commonly affects the antrum and pylorus. Malignant lesions are very rare in duodenum.

scholarly journals Histopathological spectrum of upper gastrointestinal endoscopic biopsies

2018 ◽  
Vol 1 (1) ◽  
pp. 67-74
Author(s):  
Suspana Hirachand ◽  
RR Sthapit ◽  
P Gurung ◽  
S Pradhanang ◽  
R Thapa ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Histopathological Examination ◽  
Upper Gastrointestinal Tract ◽  
Medical College ◽  
Chronic Active Gastritis ◽  
Endoscopic Biopsies ◽  
Upper Gastrointestinal Tract Endoscopy ◽  
A Prospective Study ◽  
Upper Gastrointestinal ◽  
Common Malignancy

Background: Upper gastrointestinal tract disorders are one of the most commonly encountered problems in the clinical practice. A variety of disorders can affect the upper gastrointestinal tract. Endoscopy, in combination with biopsy, plays an important role in the exact diagnosis for further management.Objectives: To determine the spectrum of histopathological lesions of upper gastrointestinal tract.Methods: A prospective study was conducted in the Department of Pathology, Kathmandu Medical College and Teaching Hospital, Nepal from January 2015 to December 2016 (2 years).Results: A total 243 endoscopic biopsies were evaluated. Out of which, 219 cases were from gastric, 15 were from esophagus and 9 were from duodenum. Among the gastric biopsies, 77 cases (35.16%) were chronic active gastritis and 27 cases (12.33%) were malignant. The most common malignancy was adenocarcinoma. Among the 15 oesophageal biopsies, 12 cases (80%) were of non-neoplastic and 3 cases (20%) were of neoplastic nature. The most common malignancy was squamous cell carcinoma. Among 9 cases of duodenum biopsies, all were non-neoplastic, of which chronic non-specific duodenitis (66.66%) was the commonest.Conclusion: Endoscopy is incomplete without histopathological examination of biopsy and so, the combinations of methods play an important role in diagnosis and management of upper gastrointestinal tract disorders.Journal of BP Koirala Institute of Health Sciences, Vol. 1, No. 1, 2018, Page: 67-74

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