scholarly journals Development and Qualification of a Novel Method for Quantitative Analysis of Lipid Aldehydes in Tissue

2020 ◽  
Vol 02 (03) ◽  
Author(s):  
William C. Putnam ◽  
Sarah M. Swenson ◽  
Dinesh Rakheja
Keyword(s):  
Quantitative Analysis ◽  
Novel Method ◽  
Lipid Aldehydes

Novel probabilistic dynamic safety metric formulations for flight path determination

2012 ◽  
Vol 227 (1) ◽  
pp. 185-198
Author(s):  
Nesrin Sarigul-Klijn ◽  
Anthony White
Keyword(s):  
Quantitative Analysis ◽  
Case Studies ◽  
East Coast ◽  
Flight Path ◽  
The Other ◽  
The West ◽  
Landing Sites ◽  
Novel Method ◽  
Safety Metrics

This article details a novel method for the determination of safe flight paths dynamically following an in-flight distress event. The method is based on probabilistic safety metrics which also include the touchdown and evacuation/rescue phases after landing. Two case studies simulating in-flight distress events, one from the west and the other from the east coast are presented using these formulations for a quantitative analysis. It is found that the nearest landing sites are not always the safest ones showing the benefits of the newly developed safety metrics. Finally, the path safety levels are plotted as a function of mission safety probability values using innovative polar plots that provide useful information to pilots.

A novel method for purification, quantitative analysis and characterization of microplastic fibers using Micro-FTIR

Chemosphere ◽  
2020 ◽  
Vol 238 ◽  
pp. 124564 ◽  
Author(s):  
Fabiana Corami ◽  
Beatrice Rosso ◽  
Barbara Bravo ◽  
Andrea Gambaro ◽  
Carlo Barbante
Keyword(s):  
Quantitative Analysis ◽  
Novel Method

Velocity Tracking–A Novel Method for Quantitative Analysis of Longitudinal Myocardial Function

2007 ◽  
Vol 20 (7) ◽  
pp. 847-856 ◽  
Author(s):  
Anna Bjällmark ◽  
Matilda Larsson ◽  
Reidar Winter ◽  
Carl Westholm ◽  
Per Jacobsen ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Myocardial Function ◽  
Novel Method ◽  
Velocity Tracking

scholarly journals Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

Blood ◽  
2013 ◽  
Vol 121 (8) ◽  
pp. e43-e49 ◽  
Author(s):  
Jing Liu ◽  
Jianhua Zhang ◽  
Yelena Ginzburg ◽  
Huihui Li ◽  
Fumin Xue ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Reliable Method ◽  
Erythroid Differentiation ◽  
Key Points ◽  
Novel Method ◽  
Terminal Erythroid Differentiation

Key Points The study establishes a reliable method to quantify differentiating mouse erythroblasts and to monitor terminal mouse erythropoiesis in vivo. Quantitative analysis of erythropoiesis of thalassemia mice revealed stage-specific changes in terminal erythroid differentiation.

Velocity tracking — A novel method for quantitative analysis of longitudinal myocardial function

2006 ◽  
Vol 39 ◽  
pp. S406
Author(s):  
M. Larsson ◽  
A. Bjällmark ◽  
R. Winter ◽  
C. Westholm ◽  
P. Jacobsen ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Myocardial Function ◽  
Novel Method ◽  
Velocity Tracking

scholarly journals Quantitative analysis of galactose using LDI-TOF MS based on a TiO2 nanowire chip

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Joo-Yoon Noh ◽  
Moon-Ju Kim ◽  
Mira Kim ◽  
Jo-Il Kim ◽  
Jong-Min Park ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Metabolic Disorders ◽  
Reduction Potential ◽  
Laser Desorption Ionization ◽  
Serum Samples ◽  
Citrate Buffer ◽  
Ionization Time ◽  
Tio2 Nanowire ◽  
Novel Method ◽  
Tof Ms

AbstractA novel method for quantifying galactose was developed to serve as a newborn screening test for galactosemia using laser desorption/ionization time-of-flight (LDI-TOF) mass spectrometry (MS) with a TiO2 nanowire chip. Herein, phosphate citrate buffer, serum, and dried blood spot (DBS) were employed for the quantitative analysis of galactose. To quantitatively analyze galactose, its reduction potential was used to oxidize o-phenylene diamine (OPD) into 2,3-diaminophenazine (DA), which were both detected using LDI-TOF MS with a TiO2 nanowire chip according to the concentration of galactose. The reproducibility and the interference of glucose were determined to demonstrate the applicability of this method. Moreover, mixtures of galactose, phenylalanine, and 17 α-OHP were analyzed to determine the interference induced by other biomarkers of metabolic disorders. The OPD oxidation of galactose was found to be selectively achieved under high-glucose conditions, similar to human blood, thereby showing good reproducibility. The intensities of the mass peaks of OPD and DA based on LDI-TOF MS with a TiO2 nanowire chip were linearly correlated in the galactose concentration range of 57.2–220.0 μg/mL (r2 = 0.999 and 0.950, respectively) for serum samples and 52.5–220.0 μg/mL (r2 = 0.993 and 0.985, respectively) for DBS after methanol precipitation/extraction. The enzyme immunoassay and LDI-TOF MS analysis results were statistically analyzed, and a mixture of phenylalanine, 17 α-OHP, and galactose was simultaneously investigated quantitatively at the cutoff level.

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