scholarly journals Evaluation of Hematocrit Level, Red Blood Cells and White Blood Cells Counts in Blood from Patients with Different Severities of Periodontal Diseases

2018 ◽  
Vol 30 (3) ◽  
pp. 1-6
Author(s):  
Chinar J Ali ◽  
Maha A Ahmed
Keyword(s):  
Chronic Disease ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Periodontal Diseases ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Control Group ◽  
Pocket Depth ◽  
Anemia Of Chronic Disease ◽  
Mean Values

Background: Anemia of chronic disease (ACD) occurs in the presence of chronic infection, inflammatory conditions or neoplastic conditions despite of adequate iron and vitamins storage. Gingivitis is the inflammation of the gingiva, periodontitis is the inflammation in the periodontium that extend deeper with loss of connective tissue attachment and supporting bone. The main pathogenesis of periodontal diseases and ACD is immune activation. Aims of study: Determine and compare the clinical periodontal parameters (plaque index (PLI), gingival index (GI), bleeding on probing (BOP), probing pocket depth (PPD) and clinical attachment level (CAL)). Evaluate the hematocrit (Hct) level, red blood cells (RBCs) count and white blood cells (WBCs) count. Assess the correlations between the clinical periodontal parameters and hematological parameters at patients had gingivitis, chronic periodontitis (CP) with different severities (mild, moderate and severe) with healthy periodontium subjects. Materials and Methods: 35-50 years old, 150 male subjects were included in this study. They were divided into three study groups: group of 30 patients with gingivitis, group of 90 patients with CP which subdivided into (Mild CP=30 patients, Moderate CP =30 patients, Severe CP =30 patients) and control group 30 subjects with clinically healthy periodontium. Blood samples were collected then by automated blood analyzer the Hct, RBCs and WBCs were evaluated. Results: Comparisons among groups and subgroups revealed significant differences in Hct and WBCs, while RBCs was non-significant. Means values of RBCs count showed reduction in mild and severe CP subgroups. while, the Hct and WBCs mean values increased in patients with periodontal disease. The correlations between the clinical periodontal parameters with WBCs and RBCs were almost non-significant but, with Hct was mostly significant negative correlations. Conclusion: Inflammatory and immune responses in periodontal diseases caused change in different hematologic parameters which could contribute to the development of anemia of chronic disease.

scholarly journals EFFECT OF DEUTERIUM WATER ON BLOOD VALUES AND DIGESTIBILITY OF NUTRIENTS OF RHESUS MACAQUE

2020 ◽  
Vol 384 (2) ◽  
pp. 22-28 ◽  
Author(s):  
N. V. Gaponov ◽  
S. V. Svistunov ◽  
N. N. Bondarenko ◽  
I. A. Romanenko
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
The Body ◽  
Control Group ◽  
Deuterium Content ◽  
Animal Blood ◽  
Constant Weight ◽  
Effect Of Water

The use of water with a modified isotopic composition in the diet of humans and animals, for example, with a reduced deuterium content, affects the rate of biological processes. In this regard, the targeted formation of the isotopic D / H gradient in the body can be used to increase its adaptive properties to external influences. Primates have a high anatomical and physiological similarity with humans, therefore, are an indispensable model for reproducing various pathological and toxic conditions in humans. The aim of the study was to study the effect of water with a low deuterium content on the hematological and biochemical blood parameters of rhesus monkeys and on the digestibility of nutrients of the diet. In the control group, primates consumed water with a natural regional content of deuterium equal to 150 mg / l, and in the experimental group - with reduced to 50 mg/l. The duration of the experiment was 35 days. The material for the study was venous blood, serum and feces of primates. Blood was drawn from monkeys before the use of deuterium depleted water and after the completion of the experiment. All blood samples (2.5-3.0 ml) were taken from the cubital or femoral veins of animals on an empty stomach and stabilized with a heparin solution. Laboratory studies of animal blood were performed on an automatic hematological analyzer (Beckman Coulter, USA) of the CoulterAcT 5diffCP brand. In order to study the effect of water with a reduced deuterium content on hematological parameters, we determined the number of red blood cells, white blood cells, platelets, hemoglobin concentration, hematocrit, the average volume of red blood cells, red blood cell anisocytosis, and erythrocyte sedimentation rate (ESR). The metabolism trial was divided into two periods. Preliminary - to exclude the influence of previous feeding and accustoming primates to cage conditions of keeping. Experimental - conducting a thorough accounting of consumed feed, excreted excrement. Feces were collected daily at the same time (morning and evening), weighed and ground in a mortar. At each collection, 50% of the homogenized mass was taken for analysis. The collected portions were stored in the refrigerator. After the end of the experimental (accounting) period in the collected feces, the initial moisture was determined by drying at 60-70 ℃ to constant weight. The resulting air-dry mass was thoroughly ground and analyzed. It has been found that the introduction of water with a reduced deuterium content into the diet of primates has a positive effect on feed conversion rate and blood biochemical parameters.

scholarly journals AMELIORATIVE ROLE OF BEE HONEY AND ROYAL JELLY AGAINST CISPLATIN INDUCED ALTERATION IN HEMATOLOGICAL PARAMETERS IN MALE WISTER ALBINO RAT

2018 ◽  
Vol 10 (4) ◽  
pp. 110 ◽  
Author(s):  
Waykar Bhalchandra ◽  
Yahya Ali Alqadhi ◽  
A. S. Ninawe
Keyword(s):  
Blood Cells ◽  
Royal Jelly ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Corpuscular Volume ◽  
Corpuscular Hemoglobin ◽  
Mean Values

Objective: This study aims to investigate the ameliorative role of dietary bee honey and royal jelly against cisplatin-induced alterations in hematological parameters in male wistar albino rat.Methods: Male wistar albino rats of same age and weight were randomly divided into four groups; G, I: control group which was given 0.9% saline, G: II: cisplatin (7 mg/kg/d) was injected intraperitoneally for 15 d, G, III bee honey with royal jelly (500 mg/kg/d of honey and 100 mg/kg/d of royal jelly) fed orally daily for 15 d, G, IV: cisplatin (7 mg/kg/d) was injected intraperitoneally and honey (500 mg/kg/d) and royal Jelly (100 mg/kg/d) fed orally daily for 15 d. The hematological parameters like total number of white blood cells (WBCs), red blood cells (RBCs), platelets, % of hemoglobin (Hb), and mean values of packed cell volume (PCV), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) were measured by using automated hematology system.Results: Cisplatin treated rats revealed a significant decrease in total number of white blood cells (WBCs), red blood cells (R. B. Cs), platelets, percentage of hemoglobin (Hb), and mean values of packed cell volume (PCV), corpuscular volume (MCV) and corpuscular hemoglobin concentration (MCHC) as compared to control group. Royal jelly and honey treated group of rats revealed a significant increase in all blood parameters compared to control group. Dietary bee honey with royal jelly along with cisplatin-treated rats revealed significant increas as compared to animals treated with cisplatin (G, II) and the computed significant valus for the above parameters are 10.00, 2.30, 8,54, 12.00, 35.00, 47.40 and 32,30 respectively.Conclusion: Bee honey and royal jelly could be used as dietary preventive natural products against cisplatin-induced hematological alterations during the treatment of cancer.

Hematological condition of breeding bulls after a long winter period of operation in the conditions of the Udmurt Republic

2022 ◽  
pp. 67-73
Author(s):  
A. Abilov ◽  
A. Azhmyakov ◽  
I. Novgorodova ◽  
N. Bogolyubova
Keyword(s):  
Red Blood Cells ◽  
Reference Values ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Winter Period ◽  
Black And White ◽  
Significant Difference ◽  
White Breed ◽  
Udmurt Republic

Purpose: to study hematological parameters of blood in bulls-producers of dairy breeds on the day of semen collection in the Udmurt Republic after a long winter period of operation, depending on the breeds, age and place of selection.Materials and methods. The work was performed at the Federal Research Center for Animal Husbandry named after Academy Member L. K. Ernst on the basis of AO "Udmurtplem" of the Udmurt Republic in the period from 2020 to 2021 on dairy bulls (n=20) aged 15-69 months, including a purebred Holstein breed of domestic selection (n=6), a Holstein black-and-white breed of European selection (the Netherlands, n=6), a black-and-white breed with blood transfusion on Holsteins on at the level of 94-98% (n=8). The content of white blood cells, red blood cells, hemoglobin and hematocrit, depending on age and breed, was studied on the ABC VET hematological analyzer on the day of taking the seed.Results. It was found that on average, in 20 bulls aged 15-69 months, the level of white blood cells was at the level of reference values of 8.8±0.25 x 109/l, red blood cells 10.3 x 1012/l, which is 50% more than the reference values. The concentration of hemoglobin is 128.0±2.92 g/l, hematocrit is on average 54.3%, with a norm of 24-46%. Breeding bulls at a reliable level, differing in age, showed that some animals had high indicators for red blood cells of 10.3±0.26 x 102, for hematocrit of 54.3% against 24-46% of reference values. Also, according to hematological indicators, there was a tendency to increase the concentration of hemoglobin and hematocrit in European-bred bulls.Conclusion. The study of the variability in hematological parameters depending on the selection showed that there is no significant difference in leukocytes and all indicators are at the level of reference values, and in erythrocytes more than 50% than the highest indicators. The highest hemoglobin values were at the level of 141-156 g/l instead of 128 g/l according to the highest reference values. Hematocrit also showed high max values in all groups in comparison with the reference values of 59-66% versus 46% in the norm. It is necessary when analyzing hematological blood parameters in addition to the average statistical indicators (M+m) also, monitor the variability (min-max) in order to obtain more objective information.

scholarly journals Physiological status of broiler chickens with diets supplemented with milk thistle extract

2021 ◽  
pp. 1319-1323
Author(s):  
Olga Bagno ◽  
Sergey Shevchenko ◽  
Antonina Shevchenko ◽  
Oleg Prokhorov ◽  
Anna Shentseva ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Broiler Chickens ◽  
Clinical Chemistry ◽  
Current Trend ◽  
White Blood Cells ◽  
Control Group ◽  
Physiological Status ◽  
Milk Thistle ◽  
Wing Vein

Background and Aim: In recent decades, the use of various feed supplements is the current trend in poultry farming, among which phytogenics serve as alternatives to feed antibiotics. This study aimed to examine the effect of feeding various doses of milk thistle extract (Silybum marianum) on the morphological and biochemical parameters of the blood in broiler chickens. Materials and Methods: Experiments were carried out in an industrial poultry farm on broiler chickens of the Hubbard ISA F15 cross for 40 days. One control group and five experimental groups of day-old chickens were formed. The number of birds in each group was 50. Broilers of all groups received complete feed, and the experimental groups received an additional milk thistle extract at doses of 0.1, 0.5, 1.0, 1.5, and 2.0 mg/kg of body weight. Milk thistle medicinal plant extract was obtained using water-ethanol extraction followed by low-temperature vacuum drying. For the assessment of blood analyses, samples were collected from the wing vein of six chickens per group. Using unified methods recommended by the International Federation of Clinical Chemistry, the content of red blood cells, hemoglobin, white blood cells, total protein, protein fractions, triglycerides, glucose, calcium, phosphorus, and the concentration of alanine aminotransferase and aspartate aminotransferase in the blood serum were determined. Results: It was found that the introduction of milk thistle extract into the diet of broiler chickens with the aforementioned doses increased the number of red blood cells, hemoglobin, white blood cells in the blood, as well as a decrease in the level of albumin and an increase in the content of γ-globulins in its serum. Conclusion: The authors assume that the introduction of milk thistle extract into a complete feed for broiler chickens increased the anabolic processes in their bodies, accompanied by increased use of proteins of the albumin fraction as the main material for organogenesis.

scholarly journals STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT

1931 ◽  
Vol 53 (5) ◽  
pp. 695-714
Author(s):  
Albert E. Casey
Keyword(s):  
Red Blood Cells ◽  
Significant Relationship ◽  
Blood Cells ◽  
Inverse Relationship ◽  
White Blood Cells ◽  
Cell Types ◽  
Normal Male ◽  
Hemoglobin Content ◽  
Mean Values ◽  
Observation Period

1. Statistical analyses have been made of the weekly variations in the blood counts of groups of normal rabbits to find whether there exists any relationship between the numerical changes occurring in the various cell types. Consecutive blood counts and differential white cell determinations on five groups of normal male rabbits comprising 45 animals in all were made at weekly intervals from October, 1927, to June, 1929, the number of observations on each group varying from eight to thirty-five. 2. The following relationships between the varying group means were found to be consistent and significant:—The number of the red blood cells varied with the amount of hemoglobin per cubic millimeter and with the number of lymphocytes. There was an inverse relationship between the amount of hemoglobin and the number of monocytes. The neutrophiles varied in number with the monocytes; the basophiles with the eosinophiles; and the eosinophiles with the monocytes. Other associations not always similar but of high significance as far as the combined values were concerned, were the relations of the red blood cells with the basophiles and the monocytes. The relations of the neutrophiles with the red blood cells and the hemoglobin were very irregular. 3. Significant association of the white blood cells with variations in the red blood cells and the hemoglobin content were observed. The numerical variations in the group means of the total white cells were associated with similar variations in the group means of the neutrophiles, the lymphocytes, the monocytes, the basophiles, and the eosinophiles almost to the degree of their numerical occurrence in the peripheral blood. 4. With the exception of the total white cells, approximately only half the variations in the group levels of the various cells and of the hemoglobin content can be accounted for on the basis of simultaneous associations with each other. 5. The red blood cells, the lymphocytes, and the basophiles as one group, the eosinophiles and the monocytes as another group, and the hemoglobin content and the neutrophiles as a third group, described a definite shift from a high to a low numerical value during the 2 year observation period. From the standpoint of the magnitude of the shift, the basophiles, the eosinophiles, the monocytes, the lymphocytes, and the red blood cells participated in the order mentioned. The neutrophiles were only slightly affected and the hemoglobin content relatively not at all. 6. No significant relationship was ever found, even in the component groups, between the weekly mean values of the following: the hemoglobin with the basophiles, the eosinophiles, or the lymphocytes; the neutrophiles with the basophiles or the eosinophiles; and the lymphocytes with the eosinophiles or the monocytes.

scholarly journals Ameliorative Effect of Chronic Supplementation of Protocatechuic Acid Alone and in Combination with Ascorbic Acid in Aniline Hydrochloride Induced Spleen Toxicity in Rats

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Upasana Khairnar ◽  
Aman Upaganlawar ◽  
Chandrashekhar Upasani
Keyword(s):  
Ascorbic Acid ◽  
Blood Cells ◽  
Protocatechuic Acid ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Feed Consumption ◽  
Control Group ◽  
Spleen Weight ◽  
Oxide Content ◽  
Aniline Hydrochloride

Background. Present study was designed to evaluate the protective effects of protocatechuic acid alone and in combination with ascorbic acid in aniline hydrochloride induced spleen toxicity in rats.Materials and Methods. Male Wistar rats of either sex (200–250 g) were used and divided into different groups. Spleen toxicity was induced by aniline hydrochloride (100 ppm) in drinking water for a period of 28 days. Treatment group received protocatechuic acid (40 mg/kg/day, p.o.), ascorbic acid (40 mg/kg/day, p.o.), and combination of protocatechuic acid (20 mg/kg/day, p.o.) and ascorbic acid (20 mg/kg/day, p.o.) followed by aniline hydrochloride. At the end of treatment period serum and tissue parameters were evaluated.Result. Rats supplemented with aniline hydrochloride showed a significant alteration in body weight, spleen weight, feed consumption, water intake, hematological parameters (haemoglobin content, red blood cells, white blood cells, and total iron content), tissue parameters (lipid peroxidation, reduced glutathione, and nitric oxide content), and membrane bound phosphatase (ATPase) compared to control group. Histopathology of aniline hydrochloride induced spleen showed significant damage compared to control rats. Treatment with protocatechuic acid along with ascorbic acid showed better protection as compared to protocatechuic acid or ascorbic acid alone in aniline hydrochloride induced spleen toxicity.Conclusion. Treatment with protocatechuic acid and ascorbic acid in combination showed significant protection in aniline hydrochloride induced splenic toxicity in rats.

scholarly journals Comparative effect of genotype and season on the haematological profile of two laying chicken strains in southwest Nigeria

2020 ◽  
Vol 53 (1) ◽  
pp. 13-18
Author(s):  
Young Imienwain Irivboje ◽  
Adeboye Olusesan Fafiolu ◽  
Muyideen Timothy Sanni ◽  
Oluwabusayo Adewunmi Irivboje ◽  
Christian Obiora Ndubuisi Ikeobi
Keyword(s):  
Red Blood Cells ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Rainy Season ◽  
White Blood Cells ◽  
Tropical Condition ◽  
Mean Values ◽  
Significant Difference ◽  
Haematological Profile

AbstractHaematological studies help in understanding the relationship of blood characteristics to the environment. One of the major environmental factors influencing haematological indicators is season. This study was aimed at the variation in haematological profiles of two strains of laying birds at different seasons. We therefore evaluated the effects of genotype and season on the haematological profile in two strains of laying birds – Dominant brown (D-192) and Hyline brown in the tropics. A total of 50 birds per strain at 30 weeks of age were randomly selected for this study. Packed cell volume (PCV) and platelets were obtained using microhaematocrit whereas red blood cells (RBC) and white blood cells (WBC) were counted using a haemocytometer. The result obtained showed that there was a significant difference (P < 0.05) in the haematological profile of the birds in the two seasons compared (rainy and dry seasons). The haematological indices obtained during the rainy season had significantly higher mean values in packed cell volume (29.65 ± 0.32%), red blood cells (2.65 ± 0.03 × 1012/L), haemoglobin (100.1 ± 0.11 g/L) and eosinophil (2.5 ± 0.16%) while those obtained during the dry season had a higher significant effect on the white blood cells (19.16 ± 0.36 × 109/L). The results further revealed that between the strains, there was no significant difference (P > 0.05) in most of the indicators analysed but Hyline brown had significantly higher values (P < 0.05) of eosinophils and platelets. We concluded that the observed differences could be a result of genetic differences between the two strains of birds which gives room for selection and that the rainy season is more favourable for laying birds production under tropical condition.

scholarly journals Гематологічні і біохімічні показники крові собак за умов застосування «Неоверму» та протекторів-антитоксикантів

2017 ◽  
Vol 19 (73) ◽  
pp. 46-49
Author(s):  
I.O. Zhukova ◽  
I.O. Kostyuk ◽  
Yu.S. Svitlychna-Kulak
Keyword(s):  
Alkaline Phosphatase ◽  
Red Blood Cells ◽  
Toxic Effect ◽  
Functional State ◽  
Blood Cells ◽  
Negative Impact ◽  
Hematological Parameters ◽  
The Body ◽  
Feed Additive ◽  
Control Group

The article presents the data on the effect of antihelmintic and imunomodulating drug «Neoverm» on the dogs’ body when the drug was administered into the stomach of the animals within three days and the results of its application in the combination with the drugs that contain antioxidant and membrane stabilizing substances. To protect the body from toxic action of «Neoverm» the drugs were used under two schemes: «E-Selenium» and «Quercetin», phospholipid hepaprotector «Lesphal» and «green buckwheat» (a feed additive – pre-ground raw buckwheat as a natural source of quercetin). The result a were compared with the control group and the group that received only «Neoverm». It has been found out that the use of «Neoverm» for the dogs both on the 7th and 14th days had a negative impact on the hematological parameters and the activity of blood enzymes that reflects the functional state of the liver. In particular, the reduction in the number of erythrocytes and the level of hemoglobin as well as the significant increase in the activity of diagnostic enzymes: alanine (ALT), asparagine (AST), gammaglutamyl (GGT) transferases and alkaline phosphatase (ALP) have been revealed. The proposed schemes to correct the toxic effect of the drug «Neoverm» in dogs led to the restoration of endogenous antitoxic resources, that is, to a gradual normalization of hematological parameters and the activity of indicatory enzymes of blood (the decrease in the activity of AST, ALT, GGT, ALP and LDH and the normalization of the number of red blood cells and hemoglobin) and that is the basis for the use of the above drugs as protectors-antioxidants when «Neoverm» is used.

scholarly journals Effect of ketorolac administration post bone cavitation surgery on some hematological parameters

2017 ◽  
Vol 41 (1) ◽  
pp. 169-177
Author(s):  
Raffal A. Omar
Keyword(s):  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Hemoglobin Concentration ◽  
Treated Group ◽  
Control Group ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Post Operation

     This study was designed to determine the effect of ketorolac on some hematological parameters post cavitation surgery in domestic rabbits. Ninety-six adult domestic local breed male rabbits were used in this study, weighing (1.23 ± 0.33) kg. They were divided randomly into two groups in the first one (n= 48/group) which represented control group, while the second one (n=48/group) represented the treated group (Ketorolac group). All rabbits in both groups undergoes surgical operation (bone cavitation in femur bone) under general anesthesia. In the Ketorolac group, animals were treated by using 30 mg/kg of Ketorolac directly post-operation and continued daily for 5 days, while in Control group no treatment was given postoperatively. The hematological parameters were recorded which include white blood cells count; red blood cells count; hemoglobin; packed cell volume; mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration; mean corpuscular volume and platelets at the period of (3, 5, 7, 14, 21, 28, 35, and 42) days post operation were estimated. Results concerning hematological values showed no significant differences in packed cell volume values between control and treated group and within each group, while haemoglobin values showed a significant decrease at period 7 and 14 days between control and treated group. Within control group the significant decrease were noticed clearly at period of 7 days. Data concerning mean corpuscular hemoglobin values within control group showed significant decrease were noticed at 5 day, but within treated group, there were no significant differences. mean corpuscular hemoglobin concentration values showed significant decrease ate period 3; 5 and 21 days between control group and treated group respectively. Within control group the significant decrease were noticed obviously at 5 days while within treated group the significant decrease were noticed at 35 days. mean corpuscular volume values showed significant increase at 3 and 5 days period between control and treated groups. Platelets counts within control group showed significant increase at period of 14 days, within treated group the significant increase were recorded at 42 days. Red blood cells showed significant decrease between control and treated groups, while within control group, the significant decrease were at 7 days. White blood cells count within treated group showed significant increase recorded at 21 days. Differential White blood cells count concerning Lymphocytes cells within control group the significant increase were recorded at 42 days  while the significant decrease were noticed at 21 days, but within treated group the significant increase were recorded at 35 days  and significant decrease were noticed at 14 days. Neutrophils counts showed significant decrease at periods 3, 14, 28 and 42 days between control and treated groups respectively; while within control group there were significant decrease at 3 days, but within treated group the significant decrease were noticed at 42 days. Monocytes cells showed significant increase at 35 days between control and treated groups, within control group there were significant increase at 35 days, while within treated group the significant increase recorded at 7 days.

scholarly journals Haematological and Genotoxic effects of cadmium chloride on Mesopotamichthys sharpeyi

2016 ◽  
Vol 13 (4) ◽  
pp. 745-752
Author(s):  
Baghdad Science Journal
Keyword(s):  
Red Blood Cells ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Cadmium Chloride ◽  
White Blood Cells ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Blood Picture ◽  
Genotoxic Effects

The present study investigated Haematological changes in Mesopotamichthys sharpeyi, as well as determination genotoxic effects of cadmium chloride on bunni fish by using 120 fingerlings, fish were distributed randomly into four treatments in addition to control group. Fish in first group treated (T1) with cadmium 0.093mg/L with changing water and added cadmium continuously, fish in the second group treated (T2) with cadmium 0.093mg/L with changing water without adding cadmium, third treatment (T3) with cadmium 0.046mg/L with changing water and adding cadmium continuously, and fourth treatment (T4) with cadmium 0.046mg/L with changing water without adding cadmium. Results of blood picture in T1 and T3 showed a significant reduction in red blood cells count, hemoglobin concentration, packed cell volume values, while the number of white blood cells showed a significant increase in its values. Results showed presence of improvement of clinical and microscopical signs and blood picture in T2 and T4, were changed water aquarium continuously and added cadmium only once compared withT1 and T3. Results of the present study concluded that changing water aquarium in the treatments without adding cadmium led to improvement of health status of fish which increased with the passage of time results of blood picture were almost the same of the control group. It could be concluded from the current study that the adding of cadmium to water aquarium containing bunni fish led to decrease in red blood cells count, hemoglobin and packed cell volume values and increase in micronuclei number.

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