scholarly journals Predoperatsionnaya terapiya statinamiu patsientov s ishemicheskoy bolezn'yu serdtsa

2011 ◽  
Vol 2 (1) ◽  
pp. 51-54
Author(s):  
Ol'ga Leonidovna Barbarash ◽  
Yuliya Vyacheslavovna Bayrakova ◽  
Evgeniya Mikhaylovna Kurguzova
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Statin Therapy ◽  
Bypass Surgery ◽  
Heart Diseases ◽  
Coronary Bypass ◽  
Ischemic Heart ◽  
Coronary Bypass Surgery ◽  
Ischemic Heart Diseases

Summary. The need for statins in patients with acute and chronic forms of coronary heart disease is now beyond doubt. However, there is still a view that from the perspective of safety it is necessary to cancel statins before a surgery and reinstitute them after a surgery. This review examines the feasibility and safety of preoperative statin therapy in patients with ischemic heart diseases before planned coronary bypass surgery.

scholarly journals Endothelial dysfunction and smoking factor in patients with coronary heart disease while testing the radial artery prior to coronary bypass surgery

2018 ◽  
Vol 16 (1) ◽  
pp. 33 ◽  
Author(s):  
O. V. Kamenskaya ◽  
L. M. Bulatetskaya ◽  
A. S. Klinkova ◽  
S. A. Alsov ◽  
A. M. Chernyavskiy
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Endothelial Dysfunction ◽  
Radial Artery ◽  
Bypass Surgery ◽  
Density Lipoprotein ◽  
Coronary Bypass ◽  
Upper Extremities ◽  
Coronary Bypass Surgery

Patients (111 males) with coronary heart disease (CHD) and angina, II-III functional class, accompanied by arterial hypertension (AH), I-III degree, in 77 % of cases (mean age was 62.00.76 years) were examined prior to coronary bypass surgery. The patients were divided into two groups: group 1 consisted of 56 nonsmoking patients (112 upper extremities) and group 2 - 55 smoking patients (110 upper extremities) with the experience of smoking being 331.6 years on average. The thumb of both the right and left hand was tested for peripheral microcirculatory blood flow (MBF) by using a laser-Doppler flowmetry method (LDF). This quantitative method was developed at our clinic to assess the adequacy of collateral circulation in the hand. The method compares MBF provided by the ulnar artery, with the radial artery occluded, with the background level. Some features of various clinical parameters in the group of smokers suffering from coronary artery disease were analyzed in comparison with those of non-smokers. Significant differences were found in the indicators of lipid profile: increased levels of total cholesterol and low-density lipoprotein (LDL) against the background of low high-density lipoprotein (HDL) in the group of smoking patients. We found out that the smokers had to apply for surgical treatment by 7 years (on average) earlier; they had a significantly greater number of heart attacks and showed the lowest body mass index (BMI). The LDF test helped to establish that smoking in patients with CHD enhances the endothelial dysfunction, while significantly reducing the reactivity of the microvascular bed under the influence of hyperemic stimulus. Sampling the radial artery for coronary artery bypass grafting in smokers tended to give negative results.

scholarly journals Dynamics of parameters of oxidative stress in blood of ischemic heart disease patients before and after coronary bypass surgery

2012 ◽  
Vol 11 (4) ◽  
pp. 13-17
Author(s):  
N. L. Vorontsova ◽  
M. V. Bogdanov ◽  
А. S. Golovkin ◽  
R. A. Mukhamadiyarov ◽  
Ye. V. Grigoriyev ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Bypass Surgery ◽  
Coronary Bypass ◽  
Ischemic Heart ◽  
Coronary Bypass Surgery ◽  
Before And After

The dynamics of indicators of inflammation, antioxidant defense and myocardium ischemia under coronary bypass surgery using artificial blood circulation and on functioning heart

2016 ◽  
Vol 22 (3) ◽  
pp. 116-120
Author(s):  
Olesya A. Rubanenko ◽  
O. V Fatenkov ◽  
S. M Khokhlunov ◽  
L. V Limareva
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Blood Circulation ◽  
Bypass Surgery ◽  
Antioxidant Defense ◽  
Coronary Bypass ◽  
Ischemic Heart ◽  
Coronary Bypass Surgery ◽  
Artificial Blood ◽  
Artificial Blood Circulation

The article considers evaluation of indicators of inflammation, antioxidant defense and myocardium ischemia in patients with ischemic heart disease exposed to coronary bypass surgery using artificial blood circulation or on functioning heart. The sampling included 96 patients distributed to two groups. The first group included 84 patients (81% of males, average age 62,2±7,7 years) exposed to coronary bypass surgery in conditions of artificial blood circulation. The second group included 12 patients (91,7% of males, average age 59,8±8,0 years) exposed to coronary bypass surgery on functioning heart without artificial blood circulation. The study demonstrated significant increasing of level of interleukin-6 in patients with ischemic heart disease after application of coronary bypass surgery with extra-corporal blood circulation that confirms high activity of inflammation factors at the given disease. The reconstructing operations on hearts in conditions of artificial blood circulation are accompanied by decreasing of concentration of superoxiddismutase. At that, the level of analyzed bio-marker remains as compared with operation on functioning heart. This occurrence testifies activation of oxidative process and intensified consumption of as factor of antioxidant defense in the course of direct re-vascularization of myocardium. The concentration of troponin increases in post-operational period of reconstructing operation but differences are unreliable when analyzed groups are compared.

scholarly journals DIABETUS MELLITUS AND SURGICAL TREATMENT OF CORONARY HEART DISEASE

2012 ◽  
Vol 67 (1) ◽  
pp. 14-19 ◽  
Author(s):  
R. S. Akchurin ◽  
E. E. Vlasova ◽  
K. V. Mershin
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Surgical Treatment ◽  
Bypass Surgery ◽  
Coronary Bypass ◽  
Coronary Bypass Surgery ◽  
Diabetic Patients ◽  
Cardio Vascular

Nearly 40-year experience of surgical treatment of coronary heart disease testifies to higher coronary heart disease (CHD) morbidity and mortality rates among diabetes mellitus patients in comparison to non-diabetic patients. At the same time, comparative study of CHD treatment methods efficacy in diabetes mellitus patients has shown that surgery is preferred to angioplasty, especially in the most severe cases – in presence of coronary occlusion, insulin-dependent diabetes and left-ventricle dysfunction. More inferior results of coronary bypass surgery in diabetic patients in comaparison to non-diabetic were conditional on a more pronounced arterial calcinosis and diffuse distal arterial involvement, as well as more severe aortal ateromatosis, flebopathy and more often wound infection occurrence. In the department of cardio-vascular surgery in Russian cardiologic scientific productive complex a quarter of all patients waiting for the coronary bypass surgery are diabetic. Selection algorithm, preoperation preparation, peculiarities of surgical technique and principles of postoperative supervision of these patients were specially designed. With adequate preparation, remission of diabetes and use of microsurgery, postoperative prognosis for these patients (both stratified and real) is comparative to that for the main group of patients. One-year follow up after the bypass surgery data testifies to the low difference in autovenous and autoarterial shunt patency in diabetic and non-diabetic patients. Long-term (10 years) survival rate is significantly lower in the group of diabetic patients. Proposed cardioprotective postoperative strategy is designed to improve both short and long-term efficacy of surgical revascularization in CHD patients with concomitant diabetes mellitus.

Hemodynamics at Rest and during Exercise in 222 Patients with Coronary Heart Disease before and after Aorto-Coronary Bypass Surgery

Cardiology ◽  
1977 ◽  
Vol 62 (3) ◽  
pp. 247-260 ◽  
Author(s):  
H. Roskamm ◽  
A. Weisswange ◽  
Ch. Hahn ◽  
K.W. Jauch ◽  
M. Schmuziger ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Bypass Surgery ◽  
Coronary Bypass ◽  
Coronary Bypass Surgery ◽  
Before And After
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