Feed intake, average daily gain, feed efficiency, and real-time ultrasound traits in Duroc pigs: II. Genome-wide association.

2014 ◽  
Author(s):  
S. Jiao ◽  
C. Maltecca ◽  
K. A. Gray ◽  
J. P. Cassady
Keyword(s):  
Real Time ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Daily Gain

PSXI-5 Genome-wide association study of feed efficiency in Russian Duroc boars

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 247-247
Author(s):  
Anna A Belous ◽  
Alexander A Sermyagin ◽  
Natalia A Zinovieva
Keyword(s):  
Feed Intake ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Genome Wide Association ◽  
Bile Acid Metabolism ◽  
Alternative Measure ◽  
Genome Wide Association Studies ◽  
Genome Wide ◽  
Conversion Rates ◽  
Daily Gain

Abstract The cost of fodder is the major part in expenditure in pork industry. In this regard, improving the feed efficiency is the main goal of breeding programs for the most of pig breeds. Residual feed intake (RFI) is an alternative measure for feed efficiency, which is accepted in different livestock species including pigs. RFI is defined as the difference between the observed and predicted feed intake based on average daily gain and (additionally) back fat thickness. Our aim was to find the candidate genes responsible for RFI in Russian Duroc boars. RFI values for individual boars (n = 766) were calculated using linear regression of daily feed intake on metabolic mid-test weight and average daily gain. The SNP genotyping was carried out using Porcine GGP HD BeadChip (GeneSeek/Neogene). After data quality control, performed in PLINK 1.9, 43,199 SNPs were selected for genome-wide association studies (GWAS). The average daily gain in studied boars was 957 g with variation in individual animals from 424 to 1508 g. Feed conversion rates averaged to 2.21 kg/kg with variation from 1.8 to 3.7 kg/kg. GWAS results showed the presence of 48 SNPs, which were significantly (P < 0.00001) associated with RFI, including 15 SNPs on SSC2, 9 SNP – SSC4, 2 SNPs – SSC6, 21 SNPs – SSC9, and 1 SNP – SSC17. A search for genes located within 0.4 Mb window (0.2 Mb down-stream to 0.2 Mb up-stream from identified SNP) revealed several putative candidates. Functional annotation of the obtained candidates showed the presence of genes involved in protein metabolism (ADAMTS2,UIMC1 on SSC2; NTNG1 on SSC4), regulation of glucose and bile acid metabolism (FGFR4 on SSC2), neuronal development (ENC1 on SSC2; NTRK1, MEF2D on SSC4), vitamin D and K pathways (BGLAP on SSC4). The study was funded by the Russian Ministry of Science and Higher Education No.0445-2019-0029.

scholarly journals A meta-analysis of genome-wide association studies for average daily gain and lean meat percentage in two Duroc pig populations

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shenping Zhou ◽  
Rongrong Ding ◽  
Fanming Meng ◽  
Xingwang Wang ◽  
Zhanwei Zhuang ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Growth And Development ◽  
Genetic Architecture ◽  
Association Studies ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
Genome Wide Association ◽  
Genome Wide Association Studies ◽  
Genome Wide ◽  
Daily Gain

Abstract Background Average daily gain (ADG) and lean meat percentage (LMP) are the main production performance indicators of pigs. Nevertheless, the genetic architecture of ADG and LMP is still elusive. Here, we conducted genome-wide association studies (GWAS) and meta-analysis for ADG and LMP in 3770 American and 2090 Canadian Duroc pigs. Results In the American Duroc pigs, one novel pleiotropic quantitative trait locus (QTL) on Sus scrofa chromosome 1 (SSC1) was identified to be associated with ADG and LMP, which spans 2.53 Mb (from 159.66 to 162.19 Mb). In the Canadian Duroc pigs, two novel QTLs on SSC1 were detected for LMP, which were situated in 3.86 Mb (from 157.99 to 161.85 Mb) and 555 kb (from 37.63 to 38.19 Mb) regions. The meta-analysis identified ten and 20 additional SNPs for ADG and LMP, respectively. Finally, four genes (PHLPP1, STC1, DYRK1B, and PIK3C2A) were detected to be associated with ADG and/or LMP. Further bioinformatics analysis showed that the candidate genes for ADG are mainly involved in bone growth and development, whereas the candidate genes for LMP mainly participated in adipose tissue and muscle tissue growth and development. Conclusions We performed GWAS and meta-analysis for ADG and LMP based on a large sample size consisting of two Duroc pig populations. One pleiotropic QTL that shared a 2.19 Mb haplotype block from 159.66 to 161.85 Mb on SSC1 was found to affect ADG and LMP in the two Duroc pig populations. Furthermore, the combination of single-population and meta-analysis of GWAS improved the efficiency of detecting additional SNPs for the analyzed traits. Our results provide new insights into the genetic architecture of ADG and LMP traits in pigs. Moreover, some significant SNPs associated with ADG and/or LMP in this study may be useful for marker-assisted selection in pig breeding.

scholarly journals 268 Administering an appeasing substance to optimize welfare and performance of receiving cattle

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 193-193
Author(s):  
Eduardo Colombo ◽  
Reinaldo F Cooke ◽  
Alice Brandão ◽  
Jacob Wiegand ◽  
Kelsey Schubach ◽  
...  
Keyword(s):  
Feed Intake ◽  
Feed Efficiency ◽  
Treatment Effects ◽  
Average Daily Gain ◽  
Plasma Concentrations ◽  
Feedlot Cattle ◽  
Skin Area ◽  
And Performance ◽  
Antimicrobial Treatments ◽  
Daily Gain

Abstract This experiment evaluated the impacts of bovine appeasing substance (BAS) administration on performance, health, and physiological responses of feedlot cattle during a 45-d receiving period. A total of 342 recently-weaned Angus-influenced steers, originating from 16 cow-calf operations, were obtained from an auction yard on d -1 and road-transported (12 h) to the feedlot. Upon arrival on d 0, body weight (BW) was recorded and steers were ranked by BW and source and assigned to receive BAS (Nutricorp, Araras, SP, Brazil; n = 171) or placebo (diethylene glycol monoethyl ether; CON; n = 171). Treatments (5 mL) were topically applied to the nuchal skin area of each animal. Within treatment, calves were allocated to 1 of 24 drylot pens (12 pens/treatment) and received a free choice total-mixed ration from d 1 to 45. Calves were assessed for bovine respiratory disease (BRD) signs and feed intake was recorded from each pen daily. Steer BW was again recorded on d 1, 7, 17, 31, and 45, whereas blood samples were collected from 5 steers/pen concurrently with each BW assessment. Average daily gain was greater (P = 0.05) in BAS vs. CON calves, although final BW did not differ (P = 0.36) between treatments. No treatment effects were detected for feed intake (P = 0.95), resulting in greater (P = 0.05) feed efficiency in BAS vs. CON steers. No treatment effects were detected (P ≥ 0.37) for plasma concentrations of haptoglobin, whereas plasma cortisol concentrations were greater (P = 0.05) in CON vs. BAS steers on d 7 (treatment × day; P = 0.07). Incidence of BRD was greater (P ≤ 0.05) in BAS vs. CON on d 6 to 10 and d 18 to 21 (treatment × day; P < 0.01), although overall BRD incidence did not differ (P = 0.24) between treatments. The number of antimicrobial treatments required per steer diagnosed with BRD symptoms to recover from sickness was greater (P = 0.04) in CON vs. BAS calves. No treatment differences were detected (P ≥ 0.41) for mortality incidence, or proportion of steers removed from the experiment due to extreme sickness. Results from this experiment indicate BAS administration upon feedlot entry improved average daily gain by enhancing feed efficiency. Administration of BAS facilitated earlier detection of BRD and reduced the need for antimicrobial treatments. Collectively, these results suggest BAS administration as a promising strategy to benefit performance and immunocompetence of feedlot receiving cattle.

PSIV-2 A comparison of feedlot growth and performance of beef x Holstein crossbred steers and Holstein steers

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 298-299
Author(s):  
Bailey L Basiel ◽  
Chad D Dechow ◽  
Tara L Felix
Keyword(s):  
Feed Intake ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Corn Silage ◽  
Department Of Agriculture ◽  
Feedlot Performance ◽  
Performance Variables ◽  
Dried Distillers Grains ◽  
And Performance ◽  
Daily Gain

Abstract Objectives were to compare feedlot performance and carcass traits of F1 beef × Holstein steers and Holstein steers. Angus or Limousin × Holstein crossbred [n = 27; age = 12 ± 3 months; body weight (BW) = 435 ± 8 kg] and Holstein (n = 20; age = 11 ± 2 months; BW = 400 ± 9 kg) steers were fed at the Pennsylvania Department of Agriculture Livestock Evaluation Center for 111 days. Feed intake was recorded using the GrowSafe Feed Intake Monitoring System (Model 4000E, GrowSafe Systems Ltd., Calgary AB, Canada). The diet contained corn silage, dried distillers grains, soybean meal, and cracked corn and was formulated to meet or exceed the requirements of beef cattle (NASEM, 2016). Growth performance variables of interest and carcass measurements were analyzed with the Mixed procedure of SAS (SAS 9.4; SAS Institute Inc., Cary, NC). USDA assigned quality grades (QG) and yield grades (YG) were analyzed the with GLIMMIX procedure of SAS. Breed was a fixed effect in all models. There were no differences (P > 0.05) between breeds in average daily gain or feed efficiency. Crossbreds exceeded Holsteins in initial (P < 0.01) and final BW (P = 0.01), dry matter intake (P = 0.03), hot carcass weight (P < 0.01), backfat (P = 0.03), and ribeye area (REA; P < 0.01). Thirty-five percent (35%) of the Holsteins received a QG of Choice or above while 74% of crossbreds graded USDA Choice or above (P = 0.01). However, 75% of Holsteins were YG 2 or lower while only 45% of crossbreds achieved YG 2 or less (P = 0.05). There was no improvement in efficiency when crossbreds were compared to Holsteins; however, carcasses from crossbreds were more likely to grade USDA Choice or above while yielding greater REA and backfat than Holsteins.

Relationships between the activity of respiratory-chain complexes in pre- (biopsy) or post-slaughter muscle samples and feed efficiency in random-bred Ghezel lambs

2017 ◽  
Vol 57 (8) ◽  
pp. 1674
Author(s):  
M. J. Zamiri ◽  
R. Mehrabi ◽  
G. R. Kavoosi ◽  
H. Rajaei Sharifabadi
Keyword(s):  
Respiratory Chain ◽  
Feed Intake ◽  
Enzyme Activities ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Chain Complex ◽  
Respiratory Chain Complex ◽  
Respiratory Chain Complexes ◽  
Chain Complexes ◽  
Daily Gain

The present study was conducted to determine the relationship between the activity of mitochondrial respiratory chain complexes in pre- and post-slaughter muscle samples and residual feed intake (RFI) in Ghezel male lambs born as a result of random mating. The study was based on the hypothesis that random-bred lambs with lower feed (or higher) RFI have lower (or higher) respiratory chain-complex activity in muscle samples. Lambs (n = 30) were fed a diet consisting of 70% concentrate and 30% alfalfa hay during a 70-day period. Individual feed intake and average daily gain were recorded to calculate the RFI, feed-conversion ratio (FCR) and adjusted FCR (aFCR). On the basis of these calculations, the lambs were classified into low and high groups for RFI, with FCR and aFCR (n = 22) being one standard deviation above or below the means; this was corroborated by Student’s t-test (P < 0.01). At the end of the experiment, a 10-g biopsy sample was taken from the posterior side of the left femoral biceps. After 24 h, the lambs were slaughtered, and a sample from the posterior side of the right femoral biceps was dissected for determination of mitochondrial protein and respiratory chain-complex activities (Complexes I–V). The RFI was not correlated with the metabolic bodyweight and average daily gain, but was positively correlated (r = 0.56) with the average daily feed intake (P < 0.01); mean daily feed intake in the low-RFI group was 200 g less than that in the high-RFI group. The FCR and aFCR were not significantly (P > 0.05) correlated with average daily feed intake (r = 0.39 and r = 0.36 respectively), but showed a negative correlation (P < 0.01) with average daily gain (r = –0.73 and r = –0.76 respectively). Although very high negative correlations were recorded between the activities of all five respiratory-chain complexes and RFI in muscle samples obtained before (–0.91 to –0.97) and after (–0.92 to –0.97) slaughter, Complexes I and V showed small negative correlations (–0.40) with FCR or aFCR (P < 0.05). Enzyme activities of the respiratory-chain Complexes I, III and V were not significantly different between the pre- and post-slaughter biopsy samples; however, the enzyme activities of respiratory-chain Complexes II and IV were slightly higher in post-slaughter samples (P < 0.01). These results suggested that it may be possible to use the enzymatic activity of respiratory-chain complexes in muscle biopsy samples for screening of lambs for RFI, providing a useful procedure for genetic selection of lambs for this component of feed efficiency. These encouraging results need to be verified in further experiments using other sheep breeds and a larger number of lambs.

Genome-wide association study for feedlot average daily gain in Nellore cattle (Bos indicus )

2014 ◽  
Vol 131 (3) ◽  
pp. 210-216 ◽  
Author(s):  
M.H.A. Santana ◽  
Y.T. Utsunomiya ◽  
H.H.R. Neves ◽  
R.C. Gomes ◽  
J.F. Garcia ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Average Daily Gain ◽  
Bos Indicus ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Nellore Cattle ◽  
Daily Gain

Feeding frequency and its effect on feedlot performance in steers

1995 ◽  
Vol 75 (2) ◽  
pp. 255-257 ◽  
Author(s):  
L. A. Goonewardene ◽  
D. F. Engstrom ◽  
D. R. ZoBell
Keyword(s):  
Feed Intake ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Mixed Diet ◽  
Feeding Frequency ◽  
Feedlot Performance ◽  
Or Efficiency ◽  
Beneficial Effects ◽  
Feedlot Steers ◽  
Daily Gain

One hundred and twenty commercial feedlot steers were penned and randomly allocated to three treatments: fed once, twice and three times per day, over a grower through finisher period of 196 d. Feeding frequency had no effect (P > 0.05) on average daily gain, feed intake or efficiency overall. We conclude that there are no beneficial effects in feeding a total mixed diet more frequently to feedlot steers. Key words: Feeding, frequency, gain, steers, feed efficiency

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