scholarly journals MEAT SCIENCE AND MUSCLE BIOLOGY SYMPOSIUM: Extracellular matrix in skeletal muscle development and meat quality1

2012 ◽  
Vol 90 (3) ◽  
pp. 922-923 ◽  
Author(s):  
M. Du ◽  
K. M. Carlin
Keyword(s):  
Skeletal Muscle ◽  
Extracellular Matrix ◽  
Muscle Development ◽  
Skeletal Muscle Development ◽  
Muscle Biology ◽  
Biology Symposium ◽  
Meat Science

scholarly journals Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases

2015 ◽  
Vol 2015 ◽  
pp. 1-17 ◽  
Author(s):  
Mao Nie ◽  
Zhong-Liang Deng ◽  
Jianming Liu ◽  
Da-Zhi Wang
Keyword(s):  
Skeletal Muscle ◽  
Molecular Mechanisms ◽  
Muscle Development ◽  
Noncoding Rnas ◽  
Skeletal Muscle Development ◽  
Wide Range ◽  
Optimal Function ◽  
Muscle Biology ◽  
Independent Life ◽  
Systematic Understanding

A healthy and independent life requires skeletal muscles to maintain optimal function throughout the lifespan, which is in turn dependent on efficient activation of processes that regulate muscle development, homeostasis, and metabolism. Thus, identifying mechanisms that modulate these processes is of crucial priority. Noncoding RNAs (ncRNAs), including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), have emerged as a class of previously unrecognized transcripts whose importance in a wide range of biological processes and human disease is only starting to be appreciated. In this review, we summarize the roles of recently identified miRNAs and lncRNAs during skeletal muscle development and pathophysiology. We also discuss several molecular mechanisms of these noncoding RNAs. Undoubtedly, further systematic understanding of these noncoding RNAs’ functions and mechanisms will not only greatly expand our knowledge of basic skeletal muscle biology, but also significantly facilitate the development of therapies for various muscle diseases, such as muscular dystrophies, cachexia, and sarcopenia.

scholarly journals The extracellular matrix dimension of skeletal muscle development

2011 ◽  
Vol 354 (2) ◽  
pp. 191-207 ◽  
Author(s):  
Sólveig Thorsteinsdóttir ◽  
Marianne Deries ◽  
Ana Sofia Cachaço ◽  
Fernanda Bajanca
Keyword(s):  
Skeletal Muscle ◽  
Extracellular Matrix ◽  
Muscle Development ◽  
Skeletal Muscle Development

scholarly journals Tiny Regulators of Massive Tissue: MicroRNAs in Skeletal Muscle Development, Myopathies, and Cancer Cachexia

2020 ◽  
Vol 10 ◽  
Author(s):  
Gurinder Bir Singh ◽  
Douglas B Cowan ◽  
Da-Zhi Wang
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
Cancer Cachexia ◽  
Muscle Development ◽  
Loss Of Function ◽  
Skeletal Muscle Development ◽  
Muscle Disorders ◽  
Muscle Biology ◽  
And Function

Skeletal muscles are the largest tissues in our body and the physiological function of muscle is essential to every aspect of life. The regulation of development, homeostasis, and metabolism is critical for the proper functioning of skeletal muscle. Consequently, understanding the processes involved in the regulation of myogenesis is of great interest. Non-coding RNAs especially microRNAs (miRNAs) are important regulators of gene expression and function. MiRNAs are small (~22 nucleotides long) noncoding RNAs known to negatively regulate target gene expression post-transcriptionally and are abundantly expressed in skeletal muscle. Gain- and loss-of function studies have revealed important roles of this class of small molecules in muscle biology and disease. In this review, we summarize the latest research that explores the role of miRNAs in skeletal muscle development, gene expression, and function as well as in muscle disorders like sarcopenia and Duchenne muscular dystrophy (DMD). Continuing with the theme of the current review series, we also briefly discuss the role of miRNAs in cancer cachexia.

scholarly journals Corrigendum to “The extracellular matrix dimension of skeletal muscle development” [Dev. Biol. 354 (2011) 191–207]

2012 ◽  
Vol 362 (1) ◽  
pp. 114
Author(s):  
Sólveig Thorsteinsdóttir ◽  
Marianne Deries ◽  
Ana Sofia Cachaço ◽  
Fernanda Bajanca
Keyword(s):  
Skeletal Muscle ◽  
Extracellular Matrix ◽  
Muscle Development ◽  
Skeletal Muscle Development

scholarly journals Extracellular matrix: an important regulator of cell functions and skeletal muscle development

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Weiya Zhang ◽  
Yuan Liu ◽  
Hong Zhang
Keyword(s):  
Skeletal Muscle ◽  
Extracellular Matrix ◽  
Connective Tissue ◽  
Muscle Tissue ◽  
Muscle Fiber ◽  
Muscle Development ◽  
Skeletal Muscle Tissue ◽  
Skeletal Muscle Development ◽  
Comprehensive Overview ◽  
Cell Functions

AbstractExtracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal lamina). These three layers of connective tissue structure can not only maintain the morphology of skeletal muscle, but also play an important role in the physiological functions of muscle cells, such as the transmission of mechanical force, the regeneration of muscle fiber, and the formation of neuromuscular junction. In this paper, detailed discussions are made for the structure and key components of ECM in skeletal muscle tissue, the role of ECM in skeletal muscle development, and the application of ECM in biomedical engineering. This review will provide the reader with a comprehensive overview of ECM, as well as a comprehensive understanding of the structure, physiological function, and application of ECM in skeletal muscle tissue.

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