1083 Proteomic analysis reveals increased Nrf2-mediated oxidative stress response in adipose tissue of late pregnant dairy cows during summer heat stress

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 519-520
Author(s):  
M. Zachut ◽  
G. Kra ◽  
G. Friedlander ◽  
Y. Levin
Keyword(s):  
Oxidative Stress ◽  
Adipose Tissue ◽  
Heat Stress ◽  
Stress Response ◽  
Dairy Cows ◽  
Proteomic Analysis ◽  
Oxidative Stress Response ◽  
Summer Heat

Proteomic analysis of the oxidative stress response inCandida albicans

PROTEOMICS ◽  
2007 ◽  
Vol 7 (5) ◽  
pp. 686-697 ◽  
Author(s):  
Harald Kusch ◽  
Susanne Engelmann ◽  
Dirk Albrecht ◽  
Joachim Morschhäuser ◽  
Michael Hecker
Keyword(s):  
Oxidative Stress ◽  
Stress Response ◽  
Proteomic Analysis ◽  
Oxidative Stress Response ◽  
Incandida Albicans

Proteomic analysis reveals oxidative stress response as the main adaptative physiological mechanism in cows under different production systems

2012 ◽  
Vol 75 (14) ◽  
pp. 4399-4411 ◽  
Author(s):  
Anna Marco-Ramell ◽  
Laura Arroyo ◽  
Yolanda Saco ◽  
Anabel García-Heredia ◽  
Jordi Camps ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stress Response ◽  
Proteomic Analysis ◽  
Production Systems ◽  
Physiological Mechanism ◽  
Oxidative Stress Response

Proteomic analysis of Sporothrix schenckii cell wall reveals proteins involved in oxidative stress response induced by menadione

2020 ◽  
Vol 141 ◽  
pp. 103987 ◽  
Author(s):  
Carlos Félix-Contreras ◽  
Carlos A. Alba-Fierro ◽  
Emmanuel Ríos-Castro ◽  
Francisco Luna-Martínez ◽  
Mayra Cuéllar-Cruz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Wall ◽  
Stress Response ◽  
Proteomic Analysis ◽  
Sporothrix Schenckii ◽  
Oxidative Stress Response

scholarly journals Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematodeCaenorhabditis remanei

2021 ◽  
Vol 11 (4) ◽  
Author(s):  
Christine H O’Connor ◽  
Kristin L Sikkink ◽  
Thomas C Nelson ◽  
Janna L Fierst ◽  
William A Cresko ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heat Stress ◽  
Stress Response ◽  
Complex Traits ◽  
Genetic Architecture ◽  
Oxidative Stress Response ◽  
Pleiotropic Effects ◽  
General View ◽  
Acute Heat Stress ◽  
And Oxidative Stress

AbstractThe adaptation of complex organisms to changing environments has been a central question in evolutionary quantitative genetics since its inception. The structure of the genotype–phenotype maps is critical because pleiotropic effects can generate widespread correlated responses to selection and potentially restrict the extent of evolutionary change. In this study, we use experimental evolution to dissect the genetic architecture of natural variation for acute heat stress and oxidative stress response in the nematode Caenorhabiditis remanei. Previous work in the classic model nematode Caenorhabiditis elegans has found that abiotic stress response is controlled by a handful of genes of major effect and that mutations in any one of these genes can have widespread pleiotropic effects on multiple stress response traits. Here, we find that acute heat stress response and acute oxidative response in C. remanei are polygenic, complex traits, with hundreds of genomic regions responding to selection. In contrast to expectation from mutation studies, we find that evolved acute heat stress and acute oxidative stress response for the most part display independent genetic bases. This lack of correlation is reflected at the levels of phenotype, gene expression, and in the genomic response to selection. Thus, while these findings support the general view that rapid adaptation can be generated by changes at hundreds to thousands of sites in the genome, the architecture of segregating variation is likely to be determined by the pleiotropic structure of the underlying genetic networks.

Sign in / Sign up

Export Citation Format

Share Document