0265 Effects of summer and winter feeding of endophyte infected tall fescue seeds on average daily gain and activity of hepatic cytochrome P450 1A, 2C, 3A, aldo-keto reductase 1C, and uridine 5'-diphospho-glucuronosyltransferase in beef steers

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 126-126
Author(s):  
B. J. McClenton ◽  
C. Waldrip ◽  
C. G. Hart ◽  
A. Theradiyil Sukumaran ◽  
C. O. Lemley ◽  
...  
EDIS ◽  
2017 ◽  
Vol 2017 (4) ◽  
Author(s):  
Philipe Moriel

Calves can be preconditioned using a wide variety of supplemental feed ingredients. However, feed ingredient selection is not the only factor to consider during a preconditioning process. Increasing the protein supply to stressed, preconditioning beef steers led to greater growth performance, and increased immune response to vaccination during a 42-day preconditioning period. Producers should not reduce the frequency of concentrate supplementation during the entire preconditioning period as it might lead to poorer vaccine response and average daily gain (consequently, less calf value at sale). However, a gradual reduction of frequency of supplementation is a supplementation strategy that can overcome these negative effects on growth and immunity, and allows producers to save on feeding and labor costs without producing lighter calves that have weaker immune responses.  


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 160-160
Author(s):  
John Wagner ◽  
William T Nelson ◽  
Terry Engle ◽  
Jerry Spears ◽  
Jeff Heldt ◽  
...  

Abstract Four hundred and thirty-two beef steers (346.3 ± 63.7 kg BW) were used to determine the effects of Zn source on feedlot cattle fed ractopamine hydrochloride. Cattle were blocked in groups of 54 by BW and housed in 48 pens containing 9 steers per pen. Pens within a weight block were randomly assigned to treatments in a 2 x 3 factorial arrangement, with factors being: 1) 0 or 30.1 mg of ractopamine HCl/kg DM fed during the final 29 days on feed; and 2) Zn source: 90 mg of supplemental Zn/kg DM from ZnSO4; Zn sulfate (67%) + Zn methionine (33%); and Zn from Zn hydroxychloride, fed through the entire feeding period. Cattle were fed a high concentrate finishing diet for 154 d and slaughtered at a commercial abattoir. Average daily gain, DMI, feed efficiency and carcass characteristics were determined after slaughter. Zinc source had no impact on live animal performance. Cattle fed ractopamine HCl had greater (P < 0.01) final BW, greater (P < 0.001) ADG, improved (P < 0.001) G:F, heavier (P < 0.01) HCW, and larger (P < 0.05) longissimus muscle compared to non-ractopamine supplemented steers. There was a Zn source by ractopamine interaction (P < 0.01) for dressing percentage. Cattle receiving ractopamine HCl with Zn hydroxychloride had a greater dressing percentage (P < 0.05) when compared to ractopamine HCl cattle fed other Zn sources. Cattle receiving ractopamine HCl with Zn sulfate had a lesser dressing percentage (P < 0.05) when compared to ractopamine HCl cattle fed other Zn sources. Additional Zn source by ractopamine HCl interactions were not significant. These data indicate that Zn source has minimal impacts on feedlot steer performance and carcass characteristics when supplemented to cattle receiving 0.0 or 30.1 mg of ractopamine HCl/kg DM.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 399-399
Author(s):  
Ibukun M Ogunade

Abstract This study applied a chemical isotope labeling/liquid chromatography mass spectrometry-based metabolomics technique to determine differences in plasma metabolites containing amine/phenol and carbonyl chemical groups in beef steers with divergent average daily gain (ADG). Thirty-eight Angus crossbred beef steers (21 d post-weaning; 210 ± 12 kg of BW) from a single source were housed in individual slatted floor pens and were fed the same total mixed ration (CP = 14.5% and NEg = 1.10 Mcal/kg) ad libitum for 42 d with free access to water. After 42 days of feeding, the steers were divided into two groups of lowest ADG (LF: n = 8) and highest (HF: n = 8) ADG. Blood samples were taken from both LF and HF steers and were immediately centrifuged to harvest the plasma. The average daily DM intake of the steers in LF and HF were 6.08 kg ± 0.57 and 6.04 kg ± 0.42, respectively, and was similar between the two groups (P = 0.72). The ADG of LF (0.99 kg ± 0.23) was lower (P = 0.01) than that of HF (1.63 kg ± 0.20). A total number of 42 carbonyl-containing metabolites and 229 amine/phenol-containing metabolites were identified in the plasma samples of both groups. No alteration in carbonyl-metabolome was detected. Ten metabolites including 4,6-dihydroxyquinoline, prolyl-valine, prolyl-leucine, prolyl-isoleucine, L-formylkynurenine, pyrocatechol, and histidine were greater in HF steers whereas 8 metabolites including arginine, phenylalanine, guanidoacetic acid, and aspartyl-threonine were greater in LF steers. This study demonstrated that beef steers with divergent ADG had altered plasma amine/phenol metabolome. Notably, plasma concentrations of dipeptides containing branched chain amino acid residues (prolyl-valine, prolyl-leucine, prolyl-isoleucine) and metabolites with anti-inflammatory and reactive oxygen-scavenging properties (4,6-dihydroxyquinoline and L-formylkynurenine) were greater in steers with high ADG.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 94-95
Author(s):  
Kelsie Webb ◽  
Ronald J Trotta ◽  
Phillip Bridges ◽  
James Matthews

Abstract To test the hypothesis that average daily gain (ADG) and clinical parameters of steers grazing novel non-toxic (NTE) or toxic KY-31 (TE) endophyte-infected tall fescue would be improved by ad libitum intake of vitamin-mineral mixes (V-M) that contain 27 ppm Se as a 1:1 blend of SELPLEX:sodium selenite (MIX) vs sodium selenite (ISe), 32 TE-naïve beef steers depleted of Se were randomly assigned to ad libitum consumption ISe vs MIX for 35 d and fed enough of a NTE/alfalfa/grain diet to achieve 0.57 kg BW gain/d. Within Se-form treatments, 2 steers were randomly assigned to each of 4, 2-acre NTE (ISe = 316 ± 31 kg, MIX = 315 ± 22 kg) or TE (ISe = 316 ± 37 kg, MIX = 314 ± 39 kg) paddocks for 84 d and had ad libitum access to their respective V-M. The MIXED procedure of SAS was used to assess effects of day, Se-form (ISe, MIX) and endophyte (NTE, TE) treatments, and their interactions. Whole blood Se decreased (P < 0.01) 31% from d 0 to 84 and was 6.2% greater (P < 0.01) for MIX steers. Serum prolactin decreased (P < 0.01) 18% for NTE and 48% for TE steers from d 0 to 84 and was 17% greater (P = 0.01) for MIX vs. ISe TE steers. Alkaline phosphatase activity (AP) decreased (P < 0.02) 27% from d 0 to 84 and was 15% greater (P < 0.02) for MIX steers. Serum urea nitrogen increased (P < 0.02) 8.2% from d 0 to 84 for TE but not NTE steers. Average daily gain (kg/d) was less (P < 0.01) in TE (-0.18) vs NTE (0.09) steers. We conclude that the ad libitum intake of MIX ameliorated the negative effects of consuming TE on serum prolactin and AP but not ADG.


2017 ◽  
Vol 95 (suppl_4) ◽  
pp. 137-137
Author(s):  
J. A. Dillon ◽  
D. D. Harmon ◽  
C. A. Rotz ◽  
D. W. Hancock

2007 ◽  
Vol 23 (2) ◽  
pp. 174-178 ◽  
Author(s):  
J.W. Waggoner ◽  
C.P. Mathis ◽  
C.A. Löest ◽  
J.E. Sawyer ◽  
F.T. McCollum ◽  
...  

1979 ◽  
Vol 59 (3) ◽  
pp. 519-529
Author(s):  
J. A. ROBERTSON ◽  
D. A. COOKE ◽  
S. E. BEACOM

Four systems of animal management were applied to a rotationally grazed mixed sward of bromegrass (Bromus inermis Leyss.) and alfalfa (Medicago media Pers.) for a period of 7 yr using yearling beef steers. The systems included (i) put and take stocking; (ii) set stocking at 2.5 steers/ha with surplus herbage conserved as silage and fed later in the season; (iii) set stocking at 3.7 steers/ha, pasture herbage supplemented with oat soilage and (iv) set stocking as in (iii), pasture herbage supplemented with dry-rolled barley. Nitrogen, at the rate of 90 kg N/ha, was applied each spring during the last 4 yr of the experiment. Forage dry matter production varied from 1760 to 5750 kg/ha between years and was highly correlated with precipitation during the growing season. Average daily gains were similar for treatments i–iii at 1.03 kg/head. Feeding supplementary barley increased rate of gain to 1.19 kg (P < 0.01), produced an additional 20 kg liveweight per steer per season and was utilized with an average efficiency of 6.6 kg dry matter per kilogram gain. Average daily gain varied significantly (P < 0.01) between years and was inversely related to dry matter production. The feeding of oat soilage or barley and the harvesting and feeding of silage reduced the variation in gain both within and between seasons compared to the put and take stocking system. Factors affecting the selection of the most appropriate management system by a producer are discussed.


2001 ◽  
Vol 81 (4) ◽  
pp. 553-561 ◽  
Author(s):  
D. R. Ouellet ◽  
J. R. Seoane ◽  
J. F. Bernier ◽  
H. Lapierre

Plasma concentrations of hormones and metabolites were measured in growing steers to establish their relation with degree of feed restriction. Sixty medium frame beef steers (259 ± 29 kg) were divided in groups of five and fed during 3 mo either timothy (T) or bromegrass (B) harvested at stem elongation of the first cut or at boot stage of the aftermath. Forages were fed at one of three levels of intake: ad libitum (FF), 80% of FF, or 65% of FF. Plasma concentrations of growth hormone (GH), insulin, glucagon, insulin-like growth factor-1 (IGF-1), glucose and nonesterfied fatty acids (NEFA) were measured on day 1 and day 78 before the morning meal. The effect of a meal on GH, insulin, glucagon, IGF-1, glucose and NEFA concentrations was also determined in 24 steers sampled from 3 h before to 3 h after a meal. Severity of feed restriction resulted in a linear decrease (P < 0.05) of plasma glucagon (0.139, 0.130, 0.121 ± 0.005 ng mL–1) and IGF-1 (109, 98, 84 ± 7 ng mL–1). Insulin concentration tended to be affected quadratically (0.37, 0.35, 0.27 ± 0.04ng mL–1 for FF, 80% of FF and 65% of FF, respectively, P < 0.10). Ingestion of a meal resulted in a decrease (P < 0.05) of GH, NEFA and glucose, and an increase of insulin concentrations (P < 0.05). There was a positive correlation (r = 0.53, P < 0.05) between IGF-1 and average daily gain, and lipid percentage of carcasses suggesting that IGF-1 is related to growth rate and fat accumulation in growing steers. Key words: Feed restriction, growth hormone, insulin, IGF-I, metabolites, grass silage


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