scholarly journals Person of the Issue: Ivan Petrovich Pavlov (1849–1936)

2014 ◽  
Vol 1 (3) ◽  
Author(s):  
Ankit Patel

Born on September 14, 1849, in Ryazan, Russia, Ivan Pavlov abandoned his early theological schooling to study science. As the Department of Physiology head at the Institute of Experimental Medicine, his groundbreaking work on the digestive systems of dogs earned him the Nobel Prize for Physiology or Medicine in 1904. Pavlov remained an active researcher until his death on February 27, 1936.

2011 ◽  
Vol 208 (12) ◽  
pp. 2347-2349 ◽  
Author(s):  
Rafi Ahmed ◽  
Bali Pulendran

This issue of the Journal of Experimental Medicine celebrates and honors the life of Ralph Steinman (1943–2011), winner of the 2011 Nobel Prize in Physiology or Medicine. Ralph’s science was rooted in fundamental discovery with the goal of translating these findings into clinical medicine. He recognized the power of immunology in treating human disease and passionately championed studies on vaccine design, immune therapy, and human immunology. One particular collaborative effort between the Steinman and Sekaly laboratories resulted in a paper published in this issue of the journal.


2011 ◽  
Vol 208 (12) ◽  
pp. 2337-2342 ◽  
Author(s):  
Carol L. Moberg

Ralph Steinman, an editor at the Journal of Experimental Medicine since 1978, shared the 2011 Nobel Prize in Physiology or Medicine for his discovery of dendritic cells (DCs) and their role in immunity. Ralph never knew. He died of pancreatic cancer on September 30, 3 days before the Nobel announcement. Unaware of his death at the time of their announcement, the Nobel Committee made the unprecedented decision that his award would stand. Ralph was the consummate physician-scientist to the end. After his diagnosis, he actively participated in his 4.5 years of treatments, creating experimental therapies using his own DCs in conjunction with the therapies devised by his physicians, all the while traveling, lecturing, and most of all pursuing new investigations in his laboratory. For 38 years—from his discovery of DCs to his Nobel Prize—Ralph pioneered the criteria and methods used to identify, isolate, grow, and study DCs. He and his colleagues demonstrated that DCs are initiators of immunity and regulators of tolerance. In his most recent studies, Ralph was harnessing the specialized features of DCs to design improved vaccines. The following synopsis describes some of his seminal discoveries.


2001 ◽  
Vol 10 (1) ◽  
pp. 4-5
Author(s):  
Thomas Hedner ◽  
Anders Himmelmann ◽  
Lennart Hansson
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