scholarly journals Parametric Testing of Chevrons on Single Flow Hot Jets

Author(s):  
James Bridges ◽  
Clifford Brown
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Megan Mariko Perron ◽  
Natalia Vasquez-Canizares ◽  
Gabriel Tarshish ◽  
Dawn M. Wahezi

Abstract Background Juvenile idiopathic inflammatory myopathies (JIIMs) is a group of autoimmune disorders, including juvenile dermatomyositis (JDM), juvenile polymyositis (JPM) and overlap myositis, that are characterized by proximal muscle weakness, elevated levels of serum muscle enzymes, and pathognomonic skin findings. While the exact etiology of JIIMs is unclear, the presence of myositis specific autoantibodies (MSAs) have been associated with certain clinical phenotypes, organ involvement and disease prognosis. To date, there have been few studies of the associations between MSA presence and patient ethnicity. It is important to understand the extent to which ethnicity impacts disease manifestations, organ involvement and clinical outcomes. The goal of our study is to determine MSA and myositis associated autoantibody (MAA) presence, clinical phenotype, and disease course in a racially diverse population of pediatric patients with JIIMs. Methods Patients age 2–21 years with a prior diagnosis of JDM, JPM or overlap myositis, who had been tested for MSA/MAA, were eligible for study inclusion. Clinical and laboratory data were collected retrospectively via manual chart review in this single-center study. Descriptive statistics were performed to summarize each variable. Given the small sample size, non-parametric testing was performed using Fischer’s exact test, Wilcoxon rank sum test and Kruskal-Wallis test. Results Thirty one patients were included in the analysis. Race and ethnicity were self-reported as Hispanic (48.4%), white (25.8%), and Black (25.8%). The most prevalent MSAs were anti-MDA5 (25.8%), anti-p155/140 (22.6%) and anti-MJ (19.4%). Presence of autoantibodies (p = 0.04) and pulmonary disease (p = 0.03) were significantly higher in patients of Black or Hispanic descent compared with white descent. Anti-MDA5 antibodies, cutaneous ulceration, cardiopulmonary involvement, hospitalizations and one death were only reported in patients with Black or Hispanic descent. Patients with anti-MDA5 antibodies were more likely to be male (p = 0.04) and to have cutaneous ulceration (p = 0.02). Conclusions This study describes the prevalence of MSA/MAA in a racially diverse group of patients with JIIM and further delineates clinical phenotype and disease complications in these groups. We found a relatively high proportion of children with anti-MDA5 antibodies and described potentially worse clinical courses in children of Black or Hispanic descent. Further investigation is warranted to examine these findings.


ChemSusChem ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 991-991
Author(s):  
Lihi Amit ◽  
Danny Naar ◽  
Robert Gloukhovski ◽  
Gerardo Jose O' ◽  
Matthew E. Suss

2021 ◽  
Vol 60 (3) ◽  
pp. 1434-1451
Author(s):  
Rui Zhou ◽  
Shouguang Yao ◽  
Yunhui Zhao ◽  
Jie Cheng
Keyword(s):  

2021 ◽  
pp. 138554
Author(s):  
R Ronen ◽  
A.D. Gat ◽  
M.Z. Bazant ◽  
M.E. Suss

2004 ◽  
Vol 126 (4) ◽  
pp. 697-702 ◽  
Author(s):  
Scott Bair

The Newtonian mixing rules for several binary systems have been experimentally investigated. Some systems show non-ideal mixing response and for some systems the non-ideal response is pressure-dependent, yielding an opportunity for manipulation of the pressure-viscosity behavior to advantage. The mixing of differing molecular weight “straight cuts” can produce very different pressure-viscosity response. This behavior underscores the difficulty in predicting the pressure-viscosity coefficient based upon chemical structure and ambient viscosity since the molecular weight distribution is also important, but it also provides another opportunity to control the high-pressure response by blending. The first experimental observation of double shear-thinning within a single flow curve is reported. Blending then provides the capability of adjusting not only the Newtonian viscosity but also the non-Newtonian shear-thinning response as well.


1996 ◽  
Vol 118 (2) ◽  
pp. 301-306 ◽  
Author(s):  
G. Ebenhoch ◽  
T. M. Speer

The design of cooling systems for gas turbine engine blades and vanes calls for efficient simulation programs. The main purpose of the described program is to determine the complete boundary condition at the coolant side to support a temperature calculation for the solid. For the simulation of convection and heat pick up of the coolant flow, pressure loss, and further effects to be found in a rotating frame, the cooling systems are represented by networks of nodes and flow elements. Within each flow element the fluid flow is modeled by a system of ordinary differential equations based on the one-dimensional conservation of mass, momentum, and energy. In this respect, the computer program differs from many other network computation programs. Concerning cooling configurations in rotating systems, the solution for a single flow element or the entire flow system is not guaranteed to be unique. This is due to rotational forces in combination with heat transfer and causes considerable computational difficulties, which can be overcome by a special path following method in which the angular velocity is selected as the parameter of homotopy. Results of the program are compared with measurements for three applications.


2001 ◽  
Vol 25 (3-4) ◽  
pp. 619-630 ◽  
Author(s):  
P Ortega Barrales ◽  
A Domı́nguez Vidal ◽  
M.L Fernández de Córdova ◽  
A Molina Dı́az

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