scholarly journals Flapping Wings and Aerodynamic Lift: The Role of Leading-Edge Vortices

AIAA Journal ◽  
2007 ◽  
Vol 45 (12) ◽  
pp. 2817-2819 ◽  
Author(s):  
Wei Shyy ◽  
Hao Liu
Keyword(s):  
Leading Edge ◽  
Flapping Wings ◽  
Aerodynamic Lift ◽  
Leading Edge Vortices

scholarly journals Dual leading-edge vortices on flapping wings

2006 ◽  
Vol 209 (24) ◽  
pp. 5005-5016 ◽  
Author(s):  
Y. Lu ◽  
G. X. Shen ◽  
G. J. Lai
Keyword(s):  
Leading Edge ◽  
Flapping Wings ◽  
Leading Edge Vortices

Vortical substructures in the shear layers forming leading-edge vortices

AIAA Journal ◽  
2002 ◽  
Vol 40 ◽  
pp. 1689-1692 ◽  
Author(s):  
A. M. Mitchell ◽  
P. Molton
Keyword(s):  
Leading Edge ◽  
Shear Layers ◽  
Leading Edge Vortices

Scaling the vorticity dynamics in the leading-edge vortices of revolving wings with two directional length scales

2020 ◽  
Vol 32 (12) ◽  
pp. 121903
Author(s):  
Nathaniel H. Werner ◽  
Junshi Wang ◽  
Haibo Dong ◽  
Azar Eslam Panah ◽  
Bo Cheng
Keyword(s):  
Leading Edge ◽  
Length Scales ◽  
Vorticity Dynamics ◽  
Leading Edge Vortices

scholarly journals Akt isoforms differentially regulate neutrophil functions

Blood ◽  
2010 ◽  
Vol 115 (21) ◽  
pp. 4237-4246 ◽  
Author(s):  
Jia Chen ◽  
Haiyang Tang ◽  
Nissim Hay ◽  
Jingsong Xu ◽  
Richard D. Ye
Keyword(s):  
Kinase Inhibitor ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Leading Edge ◽  
Neutrophil Activation ◽  
Enzyme Release ◽  
Wild Type ◽  
Akt Isoforms ◽  
Phosphoinositide 3 Kinase ◽  
O2 Production

In neutrophils, the phosphoinositide 3-kinase/Akt signaling cascade is involved in migration, degranulation, and O2− production. However, it is unclear whether the Akt kinase isoforms have distinct functions in neutrophil activation. Here we report functional differences between the 2 major Akt isoforms in neutrophil activation on the basis of studies in which we used individual Akt1 and Akt2 knockout mice. Akt2−/− neutrophils exhibited decreased cell migration, granule enzyme release, and O2− production compared with wild-type and Akt1−/− neutrophils. Surprisingly, Akt2 deficiency and pharmacologic inhibition of Akt also abrogated phorbol ester-induced O2− production, which was unaffected by treatment with the phosphoinositide 3-kinase inhibitor LY294002. The decreased O2− production in Akt2−/− neutrophils was accompanied by reduced p47phox phosphorylation and its membrane translocation, suggesting that Akt2 is important for the assembly of phagocyte nicotinamide adenine dinucleotide phosphate oxidase. In wild-type neutrophils, Akt2 but not Akt1 translocated to plasma membrane upon chemoattractant stimulation and to the leading edge in polarized neutrophils. In the absence of Akt2, chemoattractant-induced Akt protein phosphorylation was significantly reduced. These results demonstrate a predominant role of Akt2 in regulating neutrophil functions and provide evidence for differential activation of the 2 Akt isoforms in neutrophils.

The effect of a 70 deg swept canard on the leading-edge vortices of a 70 deg swept delta wing during dynamic pitching

1997 ◽  
Author(s):  
Shigeo Hayashibara ◽  
Roy Myose ◽  
L. Miller ◽  
Shigeo Hayashibara ◽  
Roy Myose ◽  
...  
Keyword(s):  
Delta Wing ◽  
Leading Edge ◽  
Leading Edge Vortices
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