scholarly journals Synthetic Modelling of Biological Communication: A Theoretical and Operational Framework for the Investigation of Minimal Life and Cognition

2018 ◽  
Vol 27 (3) ◽  
pp. 267-288 ◽  
Author(s):  
Leonardo Bich ◽  
◽  
Ramiro Frick ◽  
Keyword(s):  
Author(s):  
Xuhui Xia ◽  
Shuping Wang ◽  
Zelin Zhang ◽  
Lei Wang ◽  
Yuan Gong

Abstract In the manufacturing process of remanufactured products, balancing the life between their components is one of the important measures to achieve full utilization of waste components and sustainable economic development. In order to prolong the life cycle of remanufactured products and increase the life of parts and components, a life balance-considered matching optimization method is proposed for remanufactured parts in the process of components matching. By comprehensively considering the life matching degree of remanufactured parts and the matching success rate, a life balance-considered matching optimization model is established for remanufactured parts. We adopted an improved ant colony algorithm to solve the proposed matching model to get multiple sets of optimal component combinations with minimal life deviations between component combinations. The correctness of the model and the effectiveness of the algorithm are verified by taking the gear reducer component matching process as an example.


2013 ◽  
Vol 16 (12) ◽  
pp. 2075-2091 ◽  
Author(s):  
Sang-Hyo Kim ◽  
Moon-Seock Choi ◽  
Kwang-Il Cho ◽  
Se-Jun Park

Author(s):  
Amit Monga ◽  
Ming J. Zuo ◽  
Roger W. Toogood

A reliability-based design (RBD) of a mixed series–parallel system with deteriorative components for minimal life cycle cost is presented in this paper. Two formulations are presented based on the type of preventive maintenance modeling. These formulations incorporate the effects of preventive maintenance and minimal repairs to adjust the system failure rate. Genetic Algorithms are used to obtain an optimal system design. The economic life of the designed system is also evaluated. The results have practical applications in the area of computer integrated manufacturing where a system must perform below a given failure rate.


2018 ◽  
pp. 75-89
Author(s):  
Daniel G. Gibson ◽  
Clyde A. Hutchison ◽  
Hamilton O. Smith ◽  
J. Craig Venter
Keyword(s):  

Author(s):  
Tjerko Kamminga ◽  
Jasper J. Koehorst ◽  
Paul Vermeij ◽  
Simen-Jan Slagman ◽  
Vitor A. P. Martins dos Santos ◽  
...  

2020 ◽  
Vol 99 (10) ◽  
pp. 1170-1176
Author(s):  
Oksana V. Ushakova ◽  
Natalia V. Efimova ◽  
Aleksandr Yu. Tarasov ◽  
Elena V. Katamanova

Introduction. The problems of preserving the health of the older generation are especially significant for society and determine the need to search for key indices of medical and social well-being. The purpose of the study is to develop a method for assessing the health losses of the population of the older age group and to test using the example of the Siberian Federal District. Material and methods. For a comprehensive assessment, the following groups of indices were used: the life expectancy, mortality, morbidity, chronic diseases, cumulative disability in group 60+. An integrated assessment of health by the sum of normalized indices by the average value for the Siberian Federal District (NP) is proposed. There was using cluster analysis. Results. Dysfunctional territories (NP≥3) include: Altai Territory, Altai Republic, Irkutsk Region. 4 clusters were identified, of which the 1st cluster has the highest mortality and morbidity rates. Levels of life expectancy, the coefficient of chronicity of diseases in the IV cluster is higher than in II cluster. Cluster III is characterized by the lowest mortality, morbidity, against the background of minimal life expectancy and high cumulative disability. Discussion. The value of the proposed method is limited by the completeness of information on indices of health loss, the different availability of medical care in the territories. Conclusion. The proposed approach to assessing health losses in a group of older people has shown medical and demographic problems in the Siberian Federal District to be very different, which determines a differentiated approach to maintaining public health.


2004 ◽  
Vol 10 (3) ◽  
pp. 235-259 ◽  
Author(s):  
Kepa Ruiz-Mirazo ◽  
Alvaro Moreno

In the search for the primary roots of autonomy (a pivotal concept in Varela's comprehensive understanding of living beings), the theory of autopoiesis provided an explicit criterion to define minimal life in universal terms, and was taken as a guideline in the research program for the artificial synthesis of biological systems. Acknowledging the invaluable contribution of the autopoietic school to present biological thinking, we offer an alternative way of conceiving the most basic forms of autonomy. We give a bottom-up account of the origins of “self-production” (or self-construction, as we propose to call it), pointing out which are the minimal material and energetic requirements for the constitution of basic autonomous systems. This account is, indeed, committed to the project of developing a general theory of biology, but well grounded in the universal laws of physics and chemistry. We consider that the autopoietic theory was formulated in highly abstract terms and, in order to advance in the implementation of minimal autonomous systems (and, at the same time, make major progress in exploring the origins of life), a more specific characterization of minimal autonomous systems is required. Such a characterization will not be drawn from a review of the autopoietic criteria and terminology (à la Fleischaker) but demands a whole reformulation of the question: a proper naturalization of the concept of autonomy. Finally, we also discuss why basic autonomy, according to our account, is necessary but not sufficient for life, in contrast with Varela's idea that autopoiesis was a necessary and sufficient condition for it.


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