Mycoplasma genomics: tailoring the genome for minimal life requirements through reductive evolution

10.2741/2207 ◽  
2007 ◽  
Vol 12 (1) ◽  
pp. 2020 ◽  
Author(s):  
Ahmed Fadiel
Keyword(s):  
Reductive Evolution ◽  
Minimal Life

Life Balance-Considered Matching Optimization Method for Remanufactured Parts

2020 ◽  
Vol 20 (4) ◽  
Author(s):  
Xuhui Xia ◽  
Shuping Wang ◽  
Zelin Zhang ◽  
Lei Wang ◽  
Yuan Gong
Keyword(s):  
Life Cycle ◽  
Ant Colony Algorithm ◽  
Optimization Method ◽  
Life Balance ◽  
Matching Process ◽  
Component Matching ◽  
Matching Degree ◽  
Full Utilization ◽  
Minimal Life ◽  
Improved Ant Colony Algorithm

Abstract In the manufacturing process of remanufactured products, balancing the life between their components is one of the important measures to achieve full utilization of waste components and sustainable economic development. In order to prolong the life cycle of remanufactured products and increase the life of parts and components, a life balance-considered matching optimization method is proposed for remanufactured parts in the process of components matching. By comprehensively considering the life matching degree of remanufactured parts and the matching success rate, a life balance-considered matching optimization model is established for remanufactured parts. We adopted an improved ant colony algorithm to solve the proposed matching model to get multiple sets of optimal component combinations with minimal life deviations between component combinations. The correctness of the model and the effectiveness of the algorithm are verified by taking the gear reducer component matching process as an example.

scholarly journals Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes

Biomolecules ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 587
Author(s):  
Pascal Sirand-Pugnet ◽  
Damien Brégeon ◽  
Laure Béven ◽  
Catherine Goyenvalle ◽  
Alain Blanchard ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Horizontal Transfer ◽  
Common Ancestor ◽  
23S Rrna ◽  
Reductive Evolution ◽  
Base Modification ◽  
Chemical Solutions ◽  
Enzyme Families

The C5-methylation of uracil to form 5-methyluracil (m5U) is a ubiquitous base modification of nucleic acids. Four enzyme families have converged to catalyze this methylation using different chemical solutions. Here, we investigate the evolution of 5-methyluracil synthase families in Mollicutes, a class of bacteria that has undergone extensive genome erosion. Many mollicutes have lost some of the m5U methyltransferases present in their common ancestor. Cases of duplication and subsequent shift of function are also described. For example, most members of the Spiroplasma subgroup use the ancestral tetrahydrofolate-dependent TrmFO enzyme to catalyze the formation of m5U54 in tRNA, while a TrmFO paralog (termed RlmFO) is responsible for m5U1939 formation in 23S rRNA. RlmFO has replaced the S-adenosyl-L-methionine (SAM)-enzyme RlmD that adds the same modification in the ancestor and which is still present in mollicutes from the Hominis subgroup. Another paralog of this family, the TrmFO-like protein, has a yet unidentified function that differs from the TrmFO and RlmFO homologs. Despite having evolved towards minimal genomes, the mollicutes possess a repertoire of m5U-modifying enzymes that is highly dynamic and has undergone horizontal transfer.

Determining the Optimal Structural Target Reliability of a Structure with a Minimal Life-Cycle Cost Perspective

2013 ◽  
Vol 16 (12) ◽  
pp. 2075-2091 ◽  
Author(s):  
Sang-Hyo Kim ◽  
Moon-Seock Choi ◽  
Kwang-Il Cho ◽  
Se-Jun Park
Keyword(s):  
Life Cycle ◽  
Life Cycle Cost ◽  
Minimal Life

scholarly journals Protein moonlighting in parasitic protists

2014 ◽  
Vol 42 (6) ◽  
pp. 1734-1739 ◽  
Author(s):  
Michael L. Ginger
Keyword(s):  
Animal Models ◽  
Virulence Factors ◽  
Gene Families ◽  
Evolutionary Divergence ◽  
Reductive Evolution ◽  
Niche Adaptation ◽  
Moonlighting Proteins ◽  
Parasite Biology

Reductive evolution during the adaptation to obligate parasitism and expansions of gene families encoding virulence factors are characteristics evident to greater or lesser degrees in all parasitic protists studied to date. Large evolutionary distances separate many parasitic protists from the yeast and animal models upon which classic views of eukaryotic biochemistry are often based. Thus a combination of evolutionary divergence, niche adaptation and reductive evolution means the biochemistry of parasitic protists is often very different from their hosts and to other eukaryotes generally, making parasites intriguing subjects for those interested in the phenomenon of moonlighting proteins. In common with other organisms, the contribution of protein moonlighting to parasite biology is only just emerging, and it is not without controversy. Here, an overview of recently identified moonlighting proteins in parasitic protists is provided, together with discussion of some of the controversies.

scholarly journals Farming, slaving and enslavement: histories of endosymbioses during kinetoplastid evolution

Parasitology ◽  
2018 ◽  
Vol 145 (10) ◽  
pp. 1311-1323 ◽  
Author(s):  
Jane Harmer ◽  
Vyacheslav Yurchenko ◽  
Anna Nenarokova ◽  
Julius Lukeš ◽  
Michael L. Ginger
Keyword(s):  
Neglected Tropical Diseases ◽  
Tropical Diseases ◽  
Free Living ◽  
Reductive Evolution ◽  
Cell Divisions ◽  
Evolutionary Trajectories

AbstractParasitic trypanosomatids diverged from free-living kinetoplastid ancestors several hundred million years ago. These parasites are relatively well known, due in part to several unusual cell biological and molecular traits and in part to the significance of a few – pathogenic Leishmania and Trypanosoma species – as aetiological agents of serious neglected tropical diseases. However, the majority of trypanosomatid biodiversity is represented by osmotrophic monoxenous parasites of insects. In two lineages, novymonads and strigomonads, osmotrophic lifestyles are supported by cytoplasmic endosymbionts, providing hosts with macromolecular precursors and vitamins. Here we discuss the two independent origins of endosymbiosis within trypanosomatids and subsequently different evolutionary trajectories that see entrainment vs tolerance of symbiont cell divisions cycles within those of the host. With the potential to inform on the transition to obligate parasitism in the trypanosomatids, interest in the biology and ecology of free-living, phagotrophic kinetoplastids is beginning to enjoy a renaissance. Thus, we take the opportunity to additionally consider the wider relevance of endosymbiosis during kinetoplastid evolution, including the indulged lifestyle and reductive evolution of basal kinetoplastid Perkinsela.

scholarly journals Reductive evolution of architectural repertoires in proteomes and the birth of the tripartite world

2007 ◽  
Vol 17 (11) ◽  
pp. 1572-1585 ◽  
Author(s):  
M. Wang ◽  
L. S. Yafremava ◽  
D. Caetano-Anolles ◽  
J. E. Mittenthal ◽  
G. Caetano-Anolles
Keyword(s):  
Reductive Evolution
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